Background
: As a primary care physician, Family physician should have concern in early detection of cancer. Early detectionof malignancy is very important because usually, the disease more untreatable when cancer is discovered among the tumor markers. There is opinion that urinary hydroxyphenyl derivative is useful for detection of various kinds of cancer, recently. We study whether GIFTEC test is clinically available in respect to early detection or not.

Methods : Data gathered for in 1954 patients for general health examination during the period from May 1992 to october 1993 in Kang Dong Sacred Hospital.

Results : among 1954 ptients, 1795 patients were GIFTEC negative patients, 159 patients were GIFTEC negative patients and 4 cancer patients in GIFTEC positive patients. Therefore cancer prevalence of this study was 8/1,954(0.4%). sensitivity was 4/8(50%), specipicity was 1,791/1,946(92%) false positive rate was 155/1,946(8%), false negative rate was 4/8(50%), positive predictive value rate was 4/159(2.5%), negative predictive value rate was 1,791/1,795(99.8%).

Conclusion : In this study, although GIFTEC test is clinically available for cancer screening test for excluding cancer, but because of low sensitivity and very low rate of positive predictive value, We knew that the clinical availability of GIFTEC test for early detection of cancers was not available.