Background
: There are very few cohort studies on the hypertension in family practice. In order to investigate epidemiological characteristics of hypertensive patients and assess the safety and tolerabiliy of newly prescribed antihypertensive monotherapies in Korean patients, a prospective study was carried out.

Methods : A total of 1,181 patients were observed from July 1997 to August 1999. At 2,4,8 and 12 weeks after initiation of antihypertensive monotherapy, the patients were evaluated for whether treatment is continued and development of any adverse reactions.

Results : Calcium channel blockers(CCBs) were the most commonly prescribed initial drug class(44.2%) in family practice, followed by angiotensin converting enzyme inhibitors(ACEI) (21.0%), angiotensin II receptor antagonists(ARA) (11.8%), B-blockers(9.6%), a-blockers(3.9%), and diuretics(3.6%), During the first 12 weeks, the percentage of subjects continuing their initial ACEIs(40.7%) was substantially lower than the percentages that of subjects continuing ARAs(66.2%), a- blockers*(63.0%), CCBs(61.3%), B-blockers(55.8%), and diuretics(53.5%), respectively(P<0.001), The following adverse reactions were detected: cough(7.5%), headache(6.1%), dizziness(3.9%), flushing(3.7%), and impotence(2.4%). The incidence of cough associated with ACEI(27.9%), was higher than those of other classes(P<0.01)

Conclusion : CCBs were the most commonly prescribed initial drug class in family practice, followed by ACEIs, ARAs, B-blockers, a-blockers, and diuretics. The tolerability of antihypertensive medication was the highest in Korean patients treated with ARAs, followed by CCBs, B-blockers, diuretic, a-blocker, and ACEIs.

Background
: Hysterectomy and hysterectomy with oophorectomy are the one of the most common surgical operations, and the cases of this surgical operations have been increasing now. Moreover, the concern about hormone replacement therapy to postmenopausal women is growing now, therefore the importance of accurate information about oophorectomy state is more emphasized than before. We can get information about oophorectomy state through patient medical record and self-report, but in Korea the only available source of information in reality is patient self-report on primary care setting, regrettably. Many physicians in Korea are skeptical to self-report of patient. Therefore this study is designed to know accuracy of patient's recall about bilateral oophorectomy in whom received hystrectomy and bilateral oophorectomy through medical record review and telephone interview. And we analyze factors with the accuracy of patient's recall.

Methods : The subject of this study is the patients who is accessible through telephone interview and medical record review of those who was received hysterecomy with bilateral oophorectomy in a third grade hospital. Their surgical operations were done from Jan. 1990 to Aug. 1993. The patient proven to have malignancy was excluded. The inforamation about accuracy of their self-report and associated factor was achieved through medical record review and telephone interview.

Results : The number of accessible subject is 117. Of 117 woemn, 112(95.7%) know their hysterectomy state accurately. But the number of persons who know their own bilateral oophorectomy state accurately is 74(63.3%), and the persons who don't know their bilateral oophorectomy state accurately is 43(36.8%). Of whom who don't know accurately their bilateral oophorectomy state, 28(23.9%) women answer that they didn't know whether bilateral oophorectomy had been done or not, 15(12.8%) women denied their bilateral oophorectomy state. Women who know accurately their bilateral oophrectomy state in comparison with who don't know their bilateral oophorectomy state are younger in average age, higher in education level, and have more opportunities of listening doctor's explanation of their post organ extraction state, and have received hormone replacement therapy more. And this differences of two groups are statistically significant. The differences between two groups on monthly salary, having occupation or not, living in city or not, marital state, period after operation, pre-operative diagnosis, and whether she knows post operative diagnosis or not, are not significant statistically. The major determinants in the accurate knowledge of their own bilateral oophorectomy state are whether patients listened Doctor's personal explanation of their state or not, and whether she received hormone replacement therapy ever or not.

Conclusion : The proportion of whom know accurately their own bilateral oophorectomy state is 63.3%. That proportion is considerably low which leads to conclude that it is not advisable to make a clinical decision based on patient self-report state only in this sugical operation cases. And because the most important determinants of the accuracy knowledge of their own bilateral oophorectomy state is whether patients listened medical doctor's personal explanation of their state, therefore the importance of this aspect of doctor's education must be emphasized to medical doctors.