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Volume 37(4); July 2016

Editorial

Vitamin D Studies: Mistaking Correlation for Causation
Seung-Won Oh
Korean J Fam Med 2016;37(4):203-204.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.203

Citations

Citations to this article as recorded by  
  • A cognitive account of manipulative sympathetic magic
    Ze Hong
    Religion, Brain & Behavior.2022; 12(3): 254.     CrossRef
  • 3,922 View
  • 50 Download
  • 1 Web of Science
  • 1 Crossref

Review Article

Preventing a Mass Disease: The Case of Gallstones Disease: Role and Competence for Family Physicians
Piero Portincasa, Agostino Di Ciaula, Ignazio Grattagliano
Korean J Fam Med 2016;37(4):205-213.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.205

Gallstone formation is the result of a complex interaction between genetic and nongenetic factors. We searched and reviewed the available literature to define how the primary prevention of gallstones (cholesterol gallstones in particular) could be applied in general practice. Electronic bibliographical databases were searched. Prospective and retrospective cohort studies and case–controlled studies were analyzed and graded for evidence quality. The epidemiological data confirmed that genetic factors are estimated to account for only approximately 25% of the overall risk of gallstones, while metabolic/environmental factors are at least partially modifiable in stone-free risk groups, and are thus modifiable by primary prevention measures related to diet, lifestyle, and environmental factors (i.e., rapid weight loss, bariatric surgery, somatostatin or analogues therapy, transient gallbladder stasis, and hormone therapy). There is no specific recommendation for the secondary prevention of recurrent gallstones. Family physicians can contribute to preventing gallstones due to their capability to identify and effectively manage several risk factors discussed in this study. Although further studies are needed to better elucidate the involvement of epigenetic factors that may regulate the effect of environment and lifestyle on gene expression in the primary prevention of gallstone formation, preventive interventions are feasible and advisable in the general practice setting.

Citations

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  • Different types and numbers metabolic abnormalities and risk of gallbladder stone disease in adults
    Tingting Yang, Jianqin Zhong, Renhua Zhang, Fei Xiao, Yuan Wang, Huimin Tao, Feng Hong
    Frontiers in Nutrition.2024;[Epub]     CrossRef
  • Ten-Year Trends of Persistent Mortality With Gallstone Disease: A Retrospective Cohort Study in New Jersey
    Gregory L. Peck, Yen-Hong Kuo, Edward Nonnenmacher, Vicente H. Gracias, Shawna V. Hudson, Jason A. Roy, Brian L. Strom
    Gastro Hep Advances.2023; 2(6): 818.     CrossRef
  • Incidence of symptomatic cholelithiasis after laparoscopic sleeve gastrectomy and its association with rapid weight loss
    FaisalA Alsaif, FahadS Alabdullatif, MohammedK Aldegaither, KhalidA Alnaeem, AbdulrahmanF Alzamil, NoufH Alabdulkarim, AbdullahD Aldohayan
    Saudi Journal of Gastroenterology.2020; 26(2): 94.     CrossRef
  • An inverse association of weight and the occurrence of asymptomatic gallbladder stone disease in hypercholesterolemia patients: a case-control study
    Binwu Sheng, Qingbin Zhao, Mao Ma, Jianqin Zhang
    Lipids in Health and Disease.2020;[Epub]     CrossRef
  • Cholesterol cholelithiasis: part of a systemic metabolic disease, prone to primary prevention
    Agostino Di Ciaula, David Q-H Wang, Piero Portincasa
    Expert Review of Gastroenterology & Hepatology.2019; 13(2): 157.     CrossRef
  • An update on the pathogenesis of cholesterol gallstone disease
    Agostino Di Ciaula, David Q.-H. Wang, Piero Portincasa
    Current Opinion in Gastroenterology.2018; 34(2): 71.     CrossRef
  • Recent advances in understanding and managing cholesterol gallstones
    Agostino Di Ciaula, Piero Portincasa
    F1000Research.2018; 7: 1529.     CrossRef
  • 9,034 View
  • 65 Download
  • 6 Web of Science
  • 7 Crossref

Original Articles

Usefulness of Heavy Drinking and Binge Drinking for the Diagnosis of Alcohol Use Disorder
Seong Gu Kim, Jong Sung Kim, Han Ju Pack, Han Na Sung
Korean J Fam Med 2016;37(4):214-220.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.214
Background

This research investigated the sensitivity and specificity of heavy and binge drinking for screening of alcohol use disorder.

Methods

This retrospective study was conducted with 976 adults who visited the Sun Health Screening Center for health screenings in 2015. Daily drinking amount, drinking frequency per week, and weekly drinking amount were investigated. Using criteria from the National Institute on Alcohol Abuse and Alcoholism, participants were classified as normal drinkers, heavy drinkers, or binge drinkers, and grouped by age and sex. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of heavy and binge drinking were compared for the diagnosis of alcohol abuse and alcohol dependence using the Diagnostic and Statistical Manual of Mental Disorders (DSM) 4th edition-text revision and alcohol use disorder using the DSM 5th edition.

Results

The sensitivity of heavy and binge drinking for the diagnosis of alcohol abuse, alcohol dependence, and alcohol use disorder were 51.7%, 43.8%, and 35.3%, and 69.0%, 62.5%, and 48.2%, respectively. The specificity of these were 90.1%, 91.7%, and 95.5%, and 84.3%, 86.8%, and 91.2%, respectively. The PPV of these were 24.8%, 40.5%, and 72.7%, and 21.7%, 38.0%, and 65.2%, respectively. The NPV of these were 96.7%, 92.6%, and 81.2%, and 97.8%, 94.7%, and 83.7%, respectively.

Conclusion

Heavy and binge drinking did not show enough diagnostic power to screen DSM alcohol use disorder although they did show high specificity and NPV.

Citations

Citations to this article as recorded by  
  • ELSA cohort 2014: association of age of first drink and progression from first drink to drunkenness on alcohol outcomes in Argentinean college freshmen
    Belén del Valle Vera, Angelina Pilatti, Ricardo Marcos Pautassi
    The American Journal of Drug and Alcohol Abuse.2020; 46(1): 58.     CrossRef
  • ELSA 2014 Cohort: Risk Factors Associated With Heavy Episodic Drinking Trajectories in Argentinean College Students
    Belén del Valle Vera, Angelina Pilatti, Ricardo Marcos Pautassi
    Frontiers in Behavioral Neuroscience.2020;[Epub]     CrossRef
  • High Alcohol–Preferring Mice Show Reaction to Loss of Ethanol Reward Following Repeated Binge Drinking
    Cherish E. Ardinger, Nicholas J. Grahame, Christopher C. Lapish, David N. Linsenbardt
    Alcoholism: Clinical and Experimental Research.2020; 44(9): 1717.     CrossRef
  • Diagnostic Usefulness of Korean Standard on Heavy Drinking for the DSM-5 Alcohol Use Disorder
    Seong Gu Kim, Jong Sung Kim, Han Ju Pack, Han Na Sung
    Korean Journal of Health Promotion.2017; 17(2): 91.     CrossRef
  • 4,554 View
  • 30 Download
  • 4 Web of Science
  • 4 Crossref
The Association between Vitamin D and Health-Related Quality of Life in Korean Adults
Ji Sun Kim, Young Eun Choi, Jin Kyung Baek, Ho Jin Cho, Ye Seul Kim
Korean J Fam Med 2016;37(4):221-227.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.221
Background

We examined the relationship between vitamin D status and health-related quality of life, and explored other related factors in the general Korean population.

Methods

We used data from the 2007–2012 Korea National Health and Nutrition Examination Survey on 14,104 adults, aged 20–49 years, who had consented to serum vitamin D measurement and answered health-related quality of life questions. EuroQol-5 was used for measurement. Serum vitamin D levels were measured at intervals of 0–9.99, 10–19.99, 20–29.99, and ≥30 ng/mL.

Results

Participants with higher serum vitamin D (serum 25-hydroxyvitamin D) levels were significantly less likely to report problems with depression and anxiety. After adjustment for age, gender, income level, education level, marital status, alcohol consumption, smoking status, and the existence of depressive disorders, the odds ratio for reporting a problem with depression and anxiety was 0.60 (95% confidence interval [CI], 0.39–0.91). The odds ratio for the prevalence of any problem was 0.69 (95% CI, 0.53–0.89) before adjustment, but was not statistically significant after adjustment. No significant associations were observed for problems with mobility, self-care, usual activity, or pain and discomfort.

Conclusion

This is the first study to examine the associations between vitamin D and health-related quality of life for the general Korean population. Vitamin D status was not significantly associated with the dimensions of EuroQol-5 except for depression and anxiety problems.

Citations

Citations to this article as recorded by  
  • Higher Intakes of Nutrients are Associated with Improved Health-Related Quality of Life among Individuals with Comorbidities
    Hai Duc Nguyen
    American Journal of Lifestyle Medicine.2023; : 155982762311680.     CrossRef
  • Effectiveness of Maternal Vitamin D Supplementation in Preventing Respiratory Tract Infections in Children
    Soo Young Kim
    Korean Journal of Family Medicine.2022; 43(3): 155.     CrossRef
  • Interactions between nutrient intake and comorbidities for quality of life in premenopausal and postmenopausal women
    Hai Duc Nguyen
    Menopause.2022; 29(11): 1285.     CrossRef
  • Effects of vitamin D on mood and sleep in the healthy population: Interpretations from the serotonergic pathway
    Laura M. Huiberts, Karin C.H.J. Smolders
    Sleep Medicine Reviews.2021; 55: 101379.     CrossRef
  • Vitamin D status was not associated with anxiety, depression, or health-related quality of life in Middle Eastern and African-born immigrants in Sweden
    Lena E Granlund, Anna K Ramnemark, Christer Andersson, Marie C Lindkvist, Margareta Norberg, Eva M Fhärm
    Nutrition Research.2020; 75: 109.     CrossRef
  • Role of vitamin D deficiency in type 2 diabetes mellitus and diabetic neuropathy development
    Anna P. Stepanova, Tatiana L. Karonova, Anna A. Bystrova, Vadim B. Bregovsky
    Diabetes mellitus.2018; 21(4): 301.     CrossRef
  • Vitamin D Studies: Mistaking Correlation for Causation
    Seung-Won Oh
    Korean Journal of Family Medicine.2016; 37(4): 203.     CrossRef
  • 5,256 View
  • 61 Download
  • 9 Web of Science
  • 7 Crossref
Factors Associated with Depression Assessed by the Patient Health Questionnaire-2 in Long-Term Cancer Survivors
Ae-Jin Goo, Yun-Mi Song, Jinyoung Shin, Hyeonyoung Ko
Korean J Fam Med 2016;37(4):228-234.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.228
Background

This cross-sectional study aimed to evaluate the prevalence of depressive disorders and factors associated in long-term cancer survivors.

Methods

A total of 702 long-term cancer survivors over 5-years in remission were recruited in a university-affiliated tertiary hospital in Korea. Self-report using the Patient Health Questionnaire-2 and the Fatigue Severity Scale assessed depression and fatigue, respectively. Demographic characteristics, cancer-related clinical characteristics, comorbidity, health behaviors, and physical symptoms were assessed through the review of medical records or a structured self-administered questionnaire.

Results

We identified 26.1% of patients who had a depressed mood or displayed a loss of interest. The most prevalent primary site of cancer was the stomach (65.2%), followed by lung, breast, colorectal, and thyroid cancer. We also found that 5.7% of subjects experienced double or triple primary cancers. Larger proportion among depressive group (89.1%) complained at least one physical problem than among non-depressive group (53.2%). Physical symptoms including sleep problems, dry mouth, indigestion, pain, decreased appetite, and febrile sense were more frequent in the depressive group than in the non-depressive group. The Fatigue Severity Scale scores were higher in the depressive group than in the non-depressive group (P<0.001). Multiple logistic regression analysis showed that the highest tertile level of fatigue (odds ratio, 7.31; 95% confidence interval, 3.81–14.02) was associated with the increased risk of depression.

Conclusion

These findings suggest that careful concern about depression is necessary in long-term cancer survivors. Fatigue may be a surrogate sign for depression, and warrants further evaluation.

Citations

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  • Age-related differences in employment, insurance, and financial hardship among colorectal cancer patients: a report from the ColoCare Study
    Karely M. van Thiel Berghuijs, Heydon K. Kaddas, Gillian Trujillo, Gazelle Rouhani, Amy Chevrier, Jennifer Ose, David Shibata, Adetunji T. Toriola, Jane C. Figueiredo, Anita R. Peoples, Christopher I. Li, Sheetal Hardikar, Erin M. Siegel, Biljana Gigic, M
    Journal of Cancer Survivorship.2024; 18(3): 1075.     CrossRef
  • Global and regional geographical prevalence of depression in gastric cancer: a systematic review and meta-analysis
    Mostafa Kouhestani, Hasan Ahmadi Gharaei, Mohammad Fararouei, Hasan Hosienpour Ghahremanloo, Reza Ghaiasvand, Mostafa Dianatinasab
    BMJ Supportive & Palliative Care.2022; 12(e4): e526.     CrossRef
  • Depressive Disorder in Thyroid Cancer Patients after Thyroidectomy: A Longitudinal Follow‐up Study Using a National Cohort
    Hyo Geun Choi, Bumjung Park, Yong Bae Ji, Kyung Tae, Chang Myeon Song
    Otolaryngology–Head and Neck Surgery.2019; 160(2): 239.     CrossRef
  • A systematic review on the prevalence of symptoms of depression, anxiety and distress in long‐term cancer survivors: Implications for primary care
    Daan Brandenbarg, Saskia W. M. C. Maass, Olaf P. Geerse, Mariken E. Stegmann, Charlotte Handberg, Maya J. Schroevers, Saskia F. A. Duijts
    European Journal of Cancer Care.2019;[Epub]     CrossRef
  • Use of psychosocial services by lung cancer survivors in Germany
    Martin Eichler, Marlene Hechtner, Beatrice Wehler, Roland Buhl, Jan Stratmann, Martin Sebastian, Heinz Schmidberger, Cornelius Kortsik, Ursula Nestle, Hubert Wirtz, Thomas Wehler, Maria Blettner, Susanne Singer
    Strahlentherapie und Onkologie.2019; 195(11): 1018.     CrossRef
  • Cancer Survivorship in Primary Care
    Jihun Kang, Eun Ju Park, Jungkwon Lee
    Korean Journal of Family Medicine.2019; 40(6): 353.     CrossRef
  • Depression and survival outcomes after emergency department cancer pain visits
    Cielito C Reyes, Karen O Anderson, Carmen E Gonzalez, Haley Candra Ochs, Monica Wattana, Gyanendra Acharya, Knox H Todd
    BMJ Supportive & Palliative Care.2019; 9(4): e36.     CrossRef
  • Psychological distress in lung cancer survivors at least 1 year after diagnosis—Results of a German multicenter cross‐sectional study
    Martin Eichler, Marlene Hechtner, Beatrice Wehler, Roland Buhl, Jan Stratmann, Martin Sebastian, Heinz Schmidberger, Jessica Peuser, Cornelius Kortsik, Ursula Nestle, Sebastian Wiesemann, Hubert Wirtz, Thomas Wehler, Maria Blettner, Susanne Singer
    Psycho-Oncology.2018; 27(8): 2002.     CrossRef
  • Validation Study for the Korean Version of Fear of Cancer Recurrence Inventory
    Jinyoung Shin, Aejin Goo, Hyeonyoung Ko, Ji-Hae Kim, Seung-U Lim, Han-Kyeong Lee, Sébastien Simard, Yun-Mi Song
    Journal of Korean Medical Science.2017; 32(11): 1792.     CrossRef
  • Multimorbidity is associated with increased rates of depression in patients hospitalized with diabetes mellitus in the United States
    Charles C. Chima, Jason L. Salemi, Miranda Wang, Maria C. Mejia de Grubb, Sandra J. Gonzalez, Roger J. Zoorob
    Journal of Diabetes and its Complications.2017; 31(11): 1571.     CrossRef
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Risk of Cardiovascular Disease Using Framingham Risk Score in Korean Cancer Survivors
Ji-Hyun So, Jung-Kwon Lee, Jin-Young Shin, Wan Park
Korean J Fam Med 2016;37(4):235-241.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.235
Background

Cardiovascular disease is an important cause of morbidity and mortality in cancer survivors. The aim of this study was to investigate the modifiable cardiovascular disease risk factors and 10-year probability of the disease based on the Framingham risk score in cancer survivors, compared with the general population.

Methods

A total of 1,225 cancer survivors and 5,196 non-cancer controls who participated in the 2007–2013 Korea National Health and Nutrition Examination Surveys were enrolled. We assessed modifiable cardiovascular disease risk factors including smoking, body mass index, physical inactivity, high blood pressure, high cholesterol, and elevated blood glucose level. The 10-year probability of cardiovascular disease was determined by applying the Framingham cardiovascular disease risk equation among cancer survivors and non-cancer controls, ranging from 30 to 74 years old who had no overt cardiovascular diseases.

Results

The proportion of subjects who had higher fasting glucose levels, hemoglobin A1c levels, systolic blood pressure, and low density lipoprotein cholesterol levels, and those who had lower high density lipoprotein cholesterol levels was significantly higher in the cancer survivors than in the non-cancer controls. The average 10-year probability of cardiovascular disease among the cancer survivors was higher than that in the non-cancer controls in both men and women. The average 10-year probability of cardiovascular disease in relation to the cancer type was significantly higher in patients with hepatic, colon, lung, breast, and gastric cancer.

Conclusion

Cancer survivors have a higher cardiovascular disease risk and 10-year probability of cardiovascular disease than non-cancer controls. Control of cardiovascular disease risk factors and implementation of a well-defined cardiovascular disease prevention program are needed for treating cancer survivors.

Citations

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  • Assessing cardiovascular disease risk and social determinants of health: A comparative analysis of five risk estimation instruments using data from the Eastern Caribbean Health Outcomes Research Network
    Jeremy I. Schwartz, Christina Howitt, Sumitha Raman, Sanya Nair, Saria Hassan, Carol Oladele, Ian R. Hambleton, Daniel F. Sarpong, Oswald P. Adams, Rohan G. Maharaj, Cruz M. Nazario, Maxine Nunez, Marcella Nunez-Smith, Paulo Alexandre Azevedo Pereira Sant
    PLOS ONE.2025; 20(1): e0316577.     CrossRef
  • Cardiovascular Disease Risk in Individuals Following Plant-Based Dietary Patterns Compared to Regular Meat-Eaters
    Grace Austin, Jessica J. A. Ferguson, Shaun Eslick, Christopher Oldmeadow, Lisa G. Wood, Manohar L. Garg
    Nutrients.2024; 16(7): 1063.     CrossRef
  • Lipid Profile and Atherogenic Risk Assessment in Nigerian Breast Cancer Patients – A Cross-Sectional Study
    Ogochukwu O. Izuegbuna, Hannah O. Olawumi, Olayide S. Agodirin, Samuel A. Olatoke
    Journal of the American Nutrition Association.2024; 43(7): 582.     CrossRef
  • Predictive Performance of Cardiovascular Risk Scores in Cancer Survivors From the UK Biobank
    Celeste McCracken, Dorina-Gabriela Condurache, Liliana Szabo, Hussein Elghazaly, Fiona M. Walter, Adam J. Mead, Ronjon Chakraverty, Nicholas C. Harvey, Charlotte H. Manisty, Steffen E. Petersen, Stefan Neubauer, Zahra Raisi-Estabragh
    JACC: CardioOncology.2024; 6(4): 575.     CrossRef
  • Cancer therapy-related cardiac dysfunction and the role of cardiovascular imaging: systemic review and opinion paper from the Working Group on Cardio-Oncology of the Korean Society of Cardiology
    Iksung Cho, Seng-Chan You, Min-Jae Cha, Hui-Jeong Hwang, Eun Jeong Cho, Hee Jun Kim, Seong-Mi Park, Sung-Eun Kim, Yun-Gyoo Lee, Jong-Chan Youn, Chan Seok Park, Chi Young Shim, Woo-Baek Chung, Il Suk Sohn
    Journal of Cardiovascular Imaging.2024;[Epub]     CrossRef
  • Cancer history as a predictor in cardiovascular risk scores: a primary care cohort study
    Helen Strongman, Emily Herrett, Rod Jackson, Michael Sweeting, Alexander R Lyon, Susannah Stanway, Claire Lawson, Umesh Kadam, Liam Smeeth, Krishnan Bhaskaran
    British Journal of General Practice.2023; 73(726): e34.     CrossRef
  • Comparison of cardiovascular disease risk in women with and without breast cancer: secondary data analysis with the 2014–2018 korean national health and nutrition examination survey
    Seongmi Choi, Na-Jin Park, Mihui Kim, Kijun Song, JiYeon Choi
    BMC Public Health.2023;[Epub]     CrossRef
  • Plant-Based Dietary Patterns and Cardiovascular Disease Risk in Australians: Protocol for a Cross-Sectional Study
    Jessica Ferguson, Grace Austin, Christopher Oldmeadow, Manohar Garg
    Nutrients.2023; 15(13): 2850.     CrossRef
  • Ten-year cardiovascular risk among cancer survivors: The National Health and Nutrition Examination Survey
    Xiaochen Zhang, Meghan Pawlikowski, Susan Olivo-Marston, Karen Patricia Williams, Julie K. Bower, Ashley S. Felix, Bart Ferket
    PLOS ONE.2021; 16(3): e0247919.     CrossRef
  • Quantitative Determination of Epa and Dha in Fish Oil Capsules for Cardiovascular Disease Therapy in Indonesia by Gc-Ms
    Amelia Lorensia, Ryanto Budiono, Rivan Virlando Suryadinata, Navy Tiarasari
    Journal of Public Health Research.2021;[Epub]     CrossRef
  • Predicting Cardiovascular Disease Among Testicular Cancer Survivors After Modern Cisplatin-based Chemotherapy: Application of the Framingham Risk Score
    Darren R. Feldman, Shirin Ardeshir-Rouhani-Fard, Patrick Monahan, Howard D. Sesso, Chunkit Fung, Annalynn M. Williams, Robert J. Hamilton, David J. Vaughn, Clair J. Beard, Ryan Cook, Mohammad Abu Zaid, Steven E. Lipshultz, Lawrence H. Einhorn, Kevin C. Oe
    Clinical Genitourinary Cancer.2018; 16(4): e761.     CrossRef
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Sex Difference in the Association between Serum Homocysteine Level and Non-Alcoholic Fatty Liver Disease
Bo-Youn Won, Kyung-Chae Park, Soo-Hyun Lee, Sung-Hwan Yun, Moon-Jong Kim, Kye-Seon Park, Young-Sang Kim, Ji-Hee Haam, Hyung-Yuk Kim, Hye-Jung Kim, Ki-Hyun Park
Korean J Fam Med 2016;37(4):242-247.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.242
Background

The relationship between serum homocysteine levels and non-alcoholic fatty liver disease is poorly understood. This study aims to investigate the sex-specific relationship between serum homocysteine level and non-alcoholic fatty liver disease in the Korean population.

Methods

This cross-sectional study included 150 men and 132 women who participated in medical examination programs in Korea from January 2014 to December 2014. Patients were screened for fatty liver by abdominal ultrasound and patient blood samples were collected to measure homocysteine levels. Patients that consumed more than 20 grams of alcohol per day were excluded from this study.

Results

The homocysteine level (11.56 vs. 8.05 nmol/L) and the proportion of non-alcoholic fatty liver disease (60.7% vs. 19.7%) were significantly higher in men than in women. In men, elevated serum homocysteine levels were associated with a greater prevalence of non-alcoholic fatty liver disease (quartile 1, 43.6%; quartile 4, 80.6%; P=0.01); however, in females, there was no significant association between serum homocysteine levels and the prevalence of non-alcoholic fatty liver disease. In the logistic regression model adjusted for age and potential confounding parameters, the odds ratio for men was significantly higher in the uppermost quartile (model 3, quartile 4: odds ratio, 6.78; 95% confidential interval, 1.67 to 27.56); however, serum homocysteine levels in women were not associated with non-alcoholic fatty liver disease in the crude model or in models adjusted for confounders.

Conclusion

Serum homocysteine levels were associated with the prevalence of non-alcoholic fatty liver disease in men.

Citations

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  • Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation
    Shuai Yuan, Jie Chen, Lintao Dan, Ying Xie, Yuhao Sun, Xue Li, Susanna C Larsson
    The American Journal of Clinical Nutrition.2022; 116(6): 1595.     CrossRef
  • Genetic Association of Plasma Homocysteine Levels with Gastric Cancer Risk: A Two-Sample Mendelian Randomization Study
    Tianpei Wang, Chuanli Ren, Jing Ni, Hui Ding, Qi Qi, Caiwang Yan, Bin Deng, Juncheng Dai, Gang Li, Yanbing Ding, Guangfu Jin
    Cancer Epidemiology, Biomarkers & Prevention.2020; 29(2): 487.     CrossRef
  • Characterization of Early-Stage Alcoholic Liver Disease with Hyperhomocysteinemia and Gut Dysfunction and Associated Immune Response in Alcohol Use Disorder Patients
    Vatsalya Vatsalya, Khushboo S. Gala, Ammar Z. Hassan, Jane Frimodig, Maiying Kong, Nachiketa Sinha, Melanie L. Schwandt
    Biomedicines.2020; 9(1): 7.     CrossRef
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    Hui Pang, Qiang Fu, Qiumei Cao, Lin Hao, Zhenkun Zong
    Scientific Reports.2019;[Epub]     CrossRef
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    Haijiang Dai, Weijun Wang, Xiaohong Tang, Ruifang Chen, Zhiheng Chen, Yao Lu, Hong Yuan
    Nutrition Journal.2016;[Epub]     CrossRef
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Case Report

Multiple Cavitary Pulmonary Nodules Caused by Mycobacterium intracellulare
Sang Hoon Yoo, Seo Ree Kim, Joon Young Choi, Jae Woo Choi, Yu Mi Ko, Sun Hee Jang, Jun Kyu Park, Ye Gyu Sung, Yun Jung Park, Su Yun Oh, Se Young Bahk, Ju Hyun Lee, Myung Sook Kim
Korean J Fam Med 2016;37(4):248-252.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.248

Nontuberculous mycobacteria (NTM) have been increasingly recognized as an important cause of chronic pulmonary infections. The Mycobacterium avium complex (MAC), which is composed of two species, Mycobacterium avium and Mycobacterium intracelluare, is the most commonly encountered pathogen associated with NTM lung disease. MAC pulmonary infection typically presents in a fibrocavitary form or a nodular bronchiectatic form. However, there have been atypical presentations of MAC pulmonary infections, including solitary pulmonary nodules (SPN). There have been several previous reports of SPN due to MAC infection in the United States, Japan, and Korea. In 2009, Sekine and colleagues reported a case of MAC pulmonary infection presenting with multiple nodules. To date, however, there have been no cases of NTM lung infection with multiple cavitary pulmonary nodules, and neither a fibrotic change nor nodular bronchiectasis. The present case showed a multiple cavitating nodular lung infection due to MAC, which is very rare and different from the typical presentation of MAC pulmonary infections. We also showed that percutaneous transthoracic needle aspiration can be a useful diagnostic tool to evaluate a case of multiple cavitary nodules.

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  • Multiple pulmonary cavitating nodules in female with endometrium adenocarcinoma history – difficulties in differentiation between metastases, sarcoidosis and sarcoid-like reaction. Case report
    Alicja Gałeczka-Turkiewicz, Dagmara Galle, Agnieszka Goryczka, Maja Zarzecka, Dariusz Jastrzębski, Dariusz Ziora
    Annales Academiae Medicae Silesiensis.2023; 77: 1.     CrossRef
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    Catherine Weathered, Kelly Pennington, Patricio Escalante, Elsje Pienaar
    Journal of Theoretical Biology.2022; 534: 110949.     CrossRef
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  • 32 Download
  • 1 Web of Science
  • 2 Crossref

Brief Communication

Prevalence and Risk Factors of Domestic Violence against Iranian Women: A Cross-Sectional Study
Fathola Mohamadian, Ataollah Hashemian, Maryam Bagheri, Ashraf Direkvand-Moghadam
Korean J Fam Med 2016;37(4):253-258.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.253
Background

Violence against women in families is the most common form of violence against them. The purpose of this study was to determine the prevalence of domestic violence and its effects on married women of Ilam.

Methods

In this descriptive-sectional research, 334 married women referred to medical health centers in Ilam were selected to participate using a random sampling method. After obtaining their consent to participate in the study, participants responded to a 46 items questionnaire and responses were analyzed using IBM SPSS for Windows ver. 20.0 (IBM Co., Armonk, NY, USA).

Results

The majority of the participants reported experiencing domestic violence and emotional violence was more prevalent than other kinds of violence. Logistic regression analysis showed that lower education level, marriage at a younger age, shorter duration of marriage, fewer children, being a housewife, and husband's unemployment had a significant relationship with domestic violence against women.

Conclusion

The high prevalence of wife abuse in Ilam especially emotional violence due to lower education levels and marriage at younger age could be a serious threat for women's health as well as for other members of the family. This could be a grounding factor for other social harms such as suicide and this issue must be studied from legal, religious, and cultural standpoints.

Citations

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  • Determining domestic violence against women using machine learning methods: The case of Türkiye
    Fatma Başaran, Pınar Duru
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Letter
Hyperamylasemia Related to Sertraline
Mehmet Emin Ceylan, Alper Evrensel, Barış Önen Ünsalver
Korean J Fam Med 2016;37(4):259-259.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.259
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