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"John Alderman Linton"

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"John Alderman Linton"

Original Articles
Comparison of Metabolic Risk Factors Based on the Type of Physical Activity in Korean Adolescents: Results from a Nationwide Population-Based Survey
Min-Hyo Kim, Yaeji Lee, John Alderman Linton, Youhyun Song, Ji-Won Lee
Korean J Fam Med 2024;45(3):164-175.   Published online January 23, 2024
DOI: https://doi.org/10.4082/kjfm.23.0164
Background
Physical activity (PA) is associated with a favorable metabolic risk profile in adults. However, its role in adolescents remains unclear. In this study, using data (2019–2021) from the 8th Korea National Health and Nutrition Examination Survey, we investigated the optimal exercise type for preventing metabolic complications in adolescents.
Methods
A total of 1,222 eligible adolescent participants (12–18-year-old) were divided into four groups as follows: aerobic exercise (AE), resistance exercise (RE), combined aerobic and resistance exercise (CE), and no exercise (NE). Daily PA was assessed using the international PA questionnaire. Blood samples were collected to measure lipid, glucose, and insulin levels. Additionally, the homeostasis model assessment for insulin resistance (HOMA-IR) and triglyceride-glucose (TyG) indices were measured. Multivariate regression analysis was used to compare the metabolic risk factors across the PA groups before and after propensity score matching (PSM) adjustment for confounding variables.
Results
The CE group exhibited improved fasting glucose levels, lower TyG index, reduced white blood cell count, and higher high-density lipoprotein (HDL) cholesterol levels than the NE group. The RE group exhibited lower mean blood pressure, triglyceride, fasting insulin, HOMA-IR, TyG index and a reduced risk of metabolic syndrome than the NE group. The AE group had higher total and HDL cholesterol levels. In detailed comparison of the AE and RE groups, the RE group consistently exhibited favorable metabolic parameters, including lower blood pressure and total and low-density cholesterol levels, which persisted after PSM.
Conclusion
These findings highlight the positive effects of PA on cardiovascular risk factors in adolescents. Thus, RE may have a more favorable metabolic effect than AE. Further studies are needed to validate the benefits of exercise according to the exercise type.

Citations

Citations to this article as recorded by  
  • Reflecting on progress and challenges: the Korean Journal of Family Medicine in 2024
    Seung-Won Oh
    Korean Journal of Family Medicine.2025; 46(2): 55.     CrossRef
  • Lifestyle interventions for hypertension management in primary care: a narrative review
    Byoungduck Han, Gyu Bae Lee, Jihyun Yoon, Yang-Hyun Kim
    Ewha Medical Journal.2025; 48(4): e56.     CrossRef
  • 5,615 View
  • 101 Download
  • 2 Web of Science
  • 2 Crossref
Association between Cigarette Smoking and Sarcopenia according to Obesity in the Middle-Aged and Elderly Korean Population: The Korea National Health and Nutrition Examination Survey (2008–2011)
Yoonjoo Jo, John Alderman Linton, Junho Choi, Junghae Moon, Jungeun Kim, Jiyoung Lee, Sinae Oh
Korean J Fam Med 2019;40(2):87-92.   Published online March 20, 2019
DOI: https://doi.org/10.4082/kjfm.17.0078
Background
The definition of sarcopenia focuses on muscle mass and function. Sarcopenic obesity is the relative excess of fat tissue with decreased muscle mass. We examined the association between cigarette smoking and sarcopenia according to obesity in middle-aged and elderly Koreans.
Methods
We conducted a cross-sectional study of 9,385 subjects (age ≥50 years) based on data from the fourth and fifth Korea National Health and Nutrition Examination Surveys (2008–2011). Smoking groups were categorized by smoking status and the number of cigarettes smoked daily. Sarcopenia was defined as weight-adjusted appendicular skeletal muscle mass of 2 standard deviations below the sex-specific mean for young adults. Obesity was defined as fat mass ≥30% for men and ≥40% for women. Subjects were categorized into three groups: sarcopenic obese (SO), sarcopenic non-obese (SNO), and normal. Multiple logistic regression analysis was performed to assess the association between smoking and SNO and SO.
Results
Among men, current smokers were more associated with SNO than never-smokers (adjusted odds ratio [OR], 3.34; 95% confidence interval [CI], 1.09–10.26). However, there was no significant association between smoking status and SNO in women or SO in either sex. Among current smokers, moderate smokers (11–20 cigarettes/d) were more likely to be SNO (adjusted OR, 5.81; 95% CI, 1.12–30.31) and heavy smokers (>20 cigarettes/d) were more likely to be SO (adjusted OR, 9.53; 95% CI, 1.65–55.01) than light smokers (<11 cigarettes/d).
Conclusion
In men, smoking was positively associated with SNO, and heavy smokers were more likely to be SO than light smokers.

Citations

Citations to this article as recorded by  
  • Air pollution and muscle-fat imbalance: How PM2.5 components and ozone drive sarcopenic obesity through inflammation
    Xianzhi Li, Yajie Li, Li Yin, Qian Zhu, Shunjin Liu, Xiangyi Xing, Zonglei Zhou
    The Journal of nutrition, health and aging.2026; 30(3): 100779.     CrossRef
  • Prevalence of and risk factors for sarcopenia in patients with epilepsy
    Yu-Shiue Chen, Hung-Ling Huang, Huai-Hsien Huang, Tzu-Hsin Huang, Ming-Chi Lai, Chin-Wei Huang
    Seizure: European Journal of Epilepsy.2025; 125: 162.     CrossRef
  • Reliability and Clinical Validity of the SARC-Global Questionnaire for Sarcopenia and Sarcopenic Obesity in Spanish Older Adults
    Juan Manuel Guardia-Baena, María del Carmen Carcelén-Fraile, Fidel Hita-Contreras, Agustín Aibar-Almazán, María de los Ángeles Arévalo-Ruíz, María Aurora Mesas-Aróstegui, Raquel Fábrega-Cuadros
    Nutrients.2025; 17(7): 1206.     CrossRef
  • Association between triglyceride-glucose index and sarcopenic obesity in adults: a population-based study
    Zhengmei Zhao, Ruiting Cai, Lili Tao, Yuxiao Sun, Keping Sun
    Frontiers in Nutrition.2025;[Epub]     CrossRef
  • Oxidative balance score is inversely associated with low muscle mass in young and middle-aged adults: a cross-sectional NHANES study
    Weiliang Kong, Jiayuan Ye, Shuaiqin Dai, Xiaowei Xia, Jingjing Hu, Weiping Ding, Hui Li, Yilian Xie, Chao Cao
    BMC Musculoskeletal Disorders.2025;[Epub]     CrossRef
  • Multifactorial Determinants of Body Composition in the Korean Older Adults: Using Data from the 2022–2023 National Health and Nutrition Examination Survey
    Moonkyoung Park, ThiThu-Huyen Do, Jinsun Park
    Nutrients.2025; 17(9): 1477.     CrossRef
  • Association between total bilirubin and sarcopenia in people with type 2 diabetes: The KAMOGAWA-A study
    Shinta Yamamoto, Hiroshi Okada, Natsuko Shinagawa, Nozomi Kuramoto, Yuriko Ono, Megumi Minamida, Junya Hironaka, Chihiro Munekawa, Yuka Hasegawa, Hanako Nakajima, Nobuko Kitagawa, Takuro Okamura, Yoshitaka Hashimoto, Takafumi Osaka, Noriyuki Kitagawa, Rie
    Endocrine Journal.2025; 72(8): 887.     CrossRef
  • Metabolic dysfunction-associated steatotic liver disease: an emerging comorbidity in COPD
    Ali Al Dailaty, Ahmad Ghanem, Ghaydaa Abou Daher, Toufic Chaaban, Rajaa Chatila
    Therapeutic Advances in Chronic Disease.2025;[Epub]     CrossRef
  • Effects of Smoking on Women’s Health: A Review of Reviews
    Seung-Ah Choe
    Journal of the Korean Society for Research on Nicotine and Tobacco.2025; 16(4): 108.     CrossRef
  • The Theoretical and Practical Research of Traditional Chinese Medicine in the Prevention and Treatment of Sarcopenia
    Chunlin Hu, Xin Bao
    Journal of Contemporary Medical Practice.2024; 6(10): 42.     CrossRef
  • Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease
    Amy H. Attaway, Annette Bellar, Nicole Welch, Jinendiran Sekar, Avinash Kumar, Saurabh Mishra, Umur Hatipoğlu, Merry‐Lynn McDonald, Elizabeth A. Regan, Jonathan D. Smith, George Washko, Raúl San José Estépar, Peter Bazeley, Joe Zein, Srinivasan Dasarathy
    Journal of Cachexia, Sarcopenia and Muscle.2023; 14(2): 1083.     CrossRef
  • Higher dietary protein intake is associated with sarcopenia in older British twins
    Mary Ni Lochlainn, Ruth C E Bowyer, Ailsa A Welch, Kevin Whelan, Claire J Steves
    Age and Ageing.2023;[Epub]     CrossRef
  • The Role of Smoking in the Mechanisms of Development of Chronic Obstructive Pulmonary Disease and Atherosclerosis
    Stanislav Kotlyarov
    International Journal of Molecular Sciences.2023; 24(10): 8725.     CrossRef
  • Association between systemic immune-inflammation index and low muscle mass in US adults: a cross-sectional study
    Lin Shi, Liang Zhang, Dan Zhang, Zhuo Chen
    BMC Public Health.2023;[Epub]     CrossRef
  • Relationship between DNA methylation changes and skeletal muscle mass
    Jeong-An Gim, Sang-Yeob Lee, Seung Chan Kim, Kyung-Wan Baek, Sung Hyo Seo, Jun-Il Yoo
    BMC Genomic Data.2023;[Epub]     CrossRef
  • Tissue-specific mitochondrial toxicity of cigarette smoke concentrate: consequence to oxidative phosphorylation
    Stephen T. Decker, Alexs A. Matias, Adolfo E. Cuadra, Sean T. Bannon, Jack P. Madden, M. Enes Erol, Corinna Serviente, Karine Fenelon, Gwenael Layec
    American Journal of Physiology-Heart and Circulatory Physiology.2023; 325(5): H1088.     CrossRef
  • Association between smoking status and handgrip strength in Korean male adults: based on Korea National Health and Nutrition Examination Survey 2016–2019
    Eunbyul Cho, Hi Sun Soh, Jae-Ryun Lee, Jieun Yun, Woo Kyung Bae, Hyejin Lee
    Frontiers in Medicine.2023;[Epub]     CrossRef
  • Sleep duration and sarcopenia in adults aged ≥ 65 years from low and middle-income countries
    Lee Smith, Jae Il Shin, Nicola Veronese, Pinar Soysal, Guillermo F. López Sánchez, Damiano Pizzol, Jacopo Demurtas, Mark A. Tully, Yvonne Barnett, Laurie Butler, Ai Koyanagi
    Aging Clinical and Experimental Research.2022; 34(7): 1573.     CrossRef
  • Relationship between sarcopenia and cardiovascular disease risk among Taiwanese older adults
    Yuan-Yuei Chen, Wei-Liang Chen, Tao-Chun Peng, Fang-Yih Liaw, Yuan-Ping Chao, Tung-Wei Kao
    Public Health Nutrition.2022; 25(7): 1745.     CrossRef
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    Nutrition.2021; 81: 110898.     CrossRef
  • Relationship between smoking and the incidence of sarcopenia: The SarcoPhAge cohort
    M. Locquet, O. Bruyère, L. Lengelé, J.Y. Reginster, C. Beaudart
    Public Health.2021; 193: 101.     CrossRef
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    International Journal of Molecular Sciences.2021; 22(12): 6629.     CrossRef
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    Current Hepatology Reports.2020; 19(2): 128.     CrossRef
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    Korean Journal of Family Medicine.2019; 40(2): 61.     CrossRef
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    Korean Journal of Family Medicine.2019; 40(3): 133.     CrossRef
  • 9,375 View
  • 171 Download
  • 24 Web of Science
  • 27 Crossref
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