Citations

• Assessing cardiovascular disease risk and social determinants of health: A comparative analysis of five risk estimation instruments using data from the Eastern Caribbean Health Outcomes Research Network
  Jeremy I. Schwartz, Christina Howitt, Sumitha Raman, Sanya Nair, Saria Hassan, Carol Oladele, Ian R. Hambleton, Daniel F. Sarpong, Oswald P. Adams, Rohan G. Maharaj, Cruz M. Nazario, Maxine Nunez, Marcella Nunez-Smith, Paulo Alexandre Azevedo Pereira Sant
  PLOS ONE.2025; 20(1): e0316577.     CrossRef
• Cardiovascular Disease Risk in Individuals Following Plant-Based Dietary Patterns Compared to Regular Meat-Eaters
  Grace Austin, Jessica J. A. Ferguson, Shaun Eslick, Christopher Oldmeadow, Lisa G. Wood, Manohar L. Garg
  Nutrients.2024; 16(7): 1063.     CrossRef
• Lipid Profile and Atherogenic Risk Assessment in Nigerian Breast Cancer Patients – A Cross-Sectional Study
  Ogochukwu O. Izuegbuna, Hannah O. Olawumi, Olayide S. Agodirin, Samuel A. Olatoke
  Journal of the American Nutrition Association.2024; 43(7): 582.     CrossRef
• Predictive Performance of Cardiovascular Risk Scores in Cancer Survivors From the UK Biobank
  Celeste McCracken, Dorina-Gabriela Condurache, Liliana Szabo, Hussein Elghazaly, Fiona M. Walter, Adam J. Mead, Ronjon Chakraverty, Nicholas C. Harvey, Charlotte H. Manisty, Steffen E. Petersen, Stefan Neubauer, Zahra Raisi-Estabragh
  JACC: CardioOncology.2024; 6(4): 575.     CrossRef
• Cancer therapy-related cardiac dysfunction and the role of cardiovascular imaging: systemic review and opinion paper from the Working Group on Cardio-Oncology of the Korean Society of Cardiology
  Iksung Cho, Seng-Chan You, Min-Jae Cha, Hui-Jeong Hwang, Eun Jeong Cho, Hee Jun Kim, Seong-Mi Park, Sung-Eun Kim, Yun-Gyoo Lee, Jong-Chan Youn, Chan Seok Park, Chi Young Shim, Woo-Baek Chung, Il Suk Sohn
  Journal of Cardiovascular Imaging.2024;[Epub]     CrossRef
• Cancer history as a predictor in cardiovascular risk scores: a primary care cohort study
  Helen Strongman, Emily Herrett, Rod Jackson, Michael Sweeting, Alexander R Lyon, Susannah Stanway, Claire Lawson, Umesh Kadam, Liam Smeeth, Krishnan Bhaskaran
  British Journal of General Practice.2023; 73(726): e34.     CrossRef
• Comparison of cardiovascular disease risk in women with and without breast cancer: secondary data analysis with the 2014–2018 korean national health and nutrition examination survey
  Seongmi Choi, Na-Jin Park, Mihui Kim, Kijun Song, JiYeon Choi
  BMC Public Health.2023;[Epub]     CrossRef
• Plant-Based Dietary Patterns and Cardiovascular Disease Risk in Australians: Protocol for a Cross-Sectional Study
  Jessica Ferguson, Grace Austin, Christopher Oldmeadow, Manohar Garg
  Nutrients.2023; 15(13): 2850.     CrossRef
• Ten-year cardiovascular risk among cancer survivors: The National Health and Nutrition Examination Survey
  Xiaochen Zhang, Meghan Pawlikowski, Susan Olivo-Marston, Karen Patricia Williams, Julie K. Bower, Ashley S. Felix, Bart Ferket
  PLOS ONE.2021; 16(3): e0247919.     CrossRef
• Quantitative Determination of Epa and Dha in Fish Oil Capsules for Cardiovascular Disease Therapy in Indonesia by Gc-Ms
  Amelia Lorensia, Ryanto Budiono, Rivan Virlando Suryadinata, Navy Tiarasari
  Journal of Public Health Research.2021;[Epub]     CrossRef
• Predicting Cardiovascular Disease Among Testicular Cancer Survivors After Modern Cisplatin-based Chemotherapy: Application of the Framingham Risk Score
  Darren R. Feldman, Shirin Ardeshir-Rouhani-Fard, Patrick Monahan, Howard D. Sesso, Chunkit Fung, Annalynn M. Williams, Robert J. Hamilton, David J. Vaughn, Clair J. Beard, Ryan Cook, Mohammad Abu Zaid, Steven E. Lipshultz, Lawrence H. Einhorn, Kevin C. Oe
  Clinical Genitourinary Cancer.2018; 16(4): e761.     CrossRef

Citations

• Associations between cancer-related coping and depressive symptoms in oral cancer patients
  ChunYing Cui, Lie Wang
  BMC Psychology.2025;[Epub]     CrossRef
• Risk of Metabolic Syndrome and Fatty Liver Diseases in Gastric Cancer Survivors: A Propensity Score-Matched Analysis
  Sang Jo Han, Su Jung Baik, Young Hoon Yoon, Jie Hyun Kim, Hye Sun Lee, Soyoung Jeon, Hyojin Park
  The Korean Journal of Gastroenterology.2023; 81(4): 154.     CrossRef
• Symptomatic Features and Factors Associated With Do-Not-Resuscitate Consent in Advanced Cancer Patients Admitted to Palliative Care Ward
  Rongrong Fan, Siyu Yang, Xiaofan Bu, Yongyi Chen, Ying Wang, Boyong Shen, Cuiling Qiu, Xuying Li
  American Journal of Hospice and Palliative Medicine®.2022; 39(11): 1312.     CrossRef
• Relationship Between Symptom Distress and Fatigue Characteristics in Patients with Gastric Cancer During 1 Month after Gastrectomy
  Hui-Ying Yang, Yun-Hsiang Lee, Jin-Ming Wu, I-Rue Lai, Shiow-Ching Shun
  Clinical Nursing Research.2022; 31(3): 463.     CrossRef
• Effects of physical activity on quality of life and physical function in postoperative patients with gastrointestinal cancer
  Masaya KAJINO, Eiki TSUSHIMA
  Physical Therapy Research.2021; 24(1): 43.     CrossRef
• Common and Co-Occurring Symptoms Experienced by Patients With Gastric Cancer
  Yufen Lin, Sharron Docherty, Laura Porter, Donald Bailey
  Oncology Nursing Forum.2020; 47(2): 187.     CrossRef
• Quality of life in long-term survivors of advanced melanoma treated with checkpoint inhibitors
  Maha Mamoor, Michael A Postow, Jessica A Lavery, Shrujal S Baxi, Niloufer Khan, Jun J Mao, Lauren J Rogak, Robert Sidlow, Bridgette Thom, Jedd A Wolchok, Deborah Korenstein
  Journal for ImmunoTherapy of Cancer.2020; 8(1): e000260.     CrossRef
• Symptom experience and self-management for multiple co-occurring symptoms in patients with gastric cancer: A qualitative study
  Yufen Lin, Sharron L. Docherty, Laura S. Porter, Donald E. Bailey
  European Journal of Oncology Nursing.2020; 49: 101860.     CrossRef
• Cancer Survivorship in Primary Care
  Jihun Kang, Eun Ju Park, Jungkwon Lee
  Korean Journal of Family Medicine.2019; 40(6): 353.     CrossRef
• Resilience and positive affect contribute to lower cancer‐related fatigue among Chinese patients with gastric cancer
  Guiyuan Zou, Ye Li, Ruicai Xu, Ping Li
  Journal of Clinical Nursing.2018;[Epub]     CrossRef
• Validation of the Amharic Version of the Brief Fatigue Inventory for Assessment of Cancer-Related Fatigue in Ethiopian Cancer Patients
  Girma Tekle Gebremariam, Abel Tesfaye Anshabo, Wondemagegnhu Tigeneh, Ephrem Engidawork
  Journal of Pain and Symptom Management.2018; 56(2): 264.     CrossRef

Background
A number of observational studies have found that ginseng intake may reduce the risk of developing gastric cancer. However, studies have yielded inconsistent results as to whether consuming ginseng can lower the risk of gastric cancer. We conducted a meta-analysis of studies that assessed the association between ginseng intake and the risk of gastric cancer.Methods: We searched MEDLINE, EMBASE, CINAHL, KMbase, KoreaMed, RiCH, National Assembly Library, Riss4u, and DBPIA for studies released through August 2007. We manually searched the references. Two authors independently extracted the data. To assess the quality of the studies Scottish Intercollegiate Guidelines Network (SIGN) Methodology Checklist for case-control studies and cohort studies were used. Review Manager 5.0 (RevMan) was used for statistical analysis.Results: We identified one case-control study and three cohort studies. The risk ratio (RR) for ginseng intake of all studies was 0.83 (95% confidence interval [CI], 0.46 to 1.51) and I2 = 91% for heterogeneity. We did subgroup analysis according to different types of study design, nation, and author. The results were consistent only when we did subgroup analysis according to authors. The RR of subgroup by different authors was 1.43 (95% CI, 1.10 to 1.80) and I2 = 0% without showing heterogeneity.Conclusion: In this meta-analysis, the results suggested that there was insufficient evidence to confirm the association between ginseng intake and the risk of gastric cancer. Subsequent more powerful, well-designed, and larger observational epidemiological studies are needed to clarify the association.

Citations

• Nutritional supplements
  Hyun Ah Park, Soo Young Kim
  Journal of the Korean Medical Association.2012; 55(9): 889.     CrossRef

Hypereosinophilic syndrome is a rare disease characterized by marked peripheral eosinophilia and eosinophilic infiltration of many organs such as heart, lung, central nervous system, liver and spleen. This disease is defined by following criteria. First, sustained blood eosinophilia is greater than 1,500/mm³ longer than 6 months. Second, other apparent etiologies for eosinophilia must be absent, including parasitic infestation and allergic disease. Third, patients must have signs and symptoms of organ involvement. In Korea, some cases that eosinophil infiltrated lung, liver, gastrointestinal tract or skin were reported. In this report, we found a case showing myalgia, fatigue and eosinophilia in periodic health examination, and diagnosed hypereosinophilic syndrome.

Background
: Recently, the number of internet users is rapidly increasing and internet medical counseling for medical information is also becoming frequent. The aim of this study was to assess the responses and accuracy of internet medical counseling, and compare the responses according to years and operating groups.

Methods : The subject websites were 79 websites in August, 2000, and 88 in May, 2002, which operated board-type medical counseling. We questioned a simulated case of an acute dermatologic disease. Then we analysed the response rate, the time taken to reply and the accuracy of reponses.

Results : The number of websites that answered the question was 38 (48.1%) in 2000, and 73 (83.0%) in 2002. The response rate was significantly higher in 2002 than 2000. Time to reply was significantly shorter in 2002 than 2000. The response rate in hospital or clinic groups was higher than in other groups. The rate to make a correct diagnosis was significantly higher in 2002 than 2000. The rate to mention prognosis and necessity of intensive treatment was significantly higher in 2002 than 2000.

Conclusion : The response rate was higher 2002 than 2000. Time to reply and the accuracy of answer improved in 2002. The response rate was higher in hospital or clinic group than in other groups.

Background
: Hypertension is one of the common diseases which family physicians encounter to manage. Various research proved that appropriate aerobic exercise had effect on lowering blood pressure efficiently. This study was to find out the status of exercise, the change of exercise according to time and its predicting factors in hypertensive patients.

Methods : A total of 193 of the followed-up hypertensive patients of family physicians in Seoul and Kyoungkido from May 11, 2001 to June 10, 2001 were interviewed by doctor according to the previously designed structured questionnaire.

Results : Eighty two patients (42.5%) were male and mean age was 57.4±9.9 years. Using Kaplan-Meier's method, 8% of non-exercise group (N=115) in diagnosing hypertension started exercise after 1 year and 40%, after 5 years. Otherwise, 5% of exercise group(N=78) stopped exercise after 1 year and 30%, after 5 years. The characteristics of 5 exercise groups according to sex, age, level of education and adequacy of exercise showed significant difference. In average blood pressure, lately started group showed the lowest (137/84 mmHg) and non-exercise group, the highest (146/91mmHg). In the degree of recommendation, sporadic group showed the highest and non-exercise group, the lowest which showed significant difference(p=0.0024).

Conclusion : I conclude that lately started group among non-exercise group and continuous exercise group were mainly affected by recommendation to exercise of physician. As well as exercise, other nonpharmacologic treatment should be promoted by physician as an important strategy for treatment of hypertension.

Background
: Pusan is geographically far away from the indigenous area of malaria. it is the area were the tourists and foreigners travel through frequently because of the port. We investigated the situation in Pusan concerning malaria through the examination of malaria patients who contracted it recently. We found the ways to decrease erroneous diagnosis presuming malaria on the basis of these studies.

Methods : We retrospectively analyzed the medical records of 28 confirmed cases of malaria with the chief complaint of repeated high fever, who were admitted and treated in the Pusan Adventist Hospital and Pusan Samsun Hospital from June 1997 to August 2000.

Results : 25 cases were indigenous and 3 patients were imported cases contracted overseas. Peripheral blood smears revealed Plasmodium vivax in all indigenous cases, wheresa 2 were P. falciparum and I case was P. vivax in the imported cases. Yeonchon-goon(9 cases) was the most prevalent area in the indigenous cases. Africa and Southeast Asia (3 cases) were the contracted aresa in the imported cases. 27 cases were men and 1 case was a women among the 28 cases, and the incidence was high peak in 8 - 10 month. Most of the patients(72.1%) were in the their 20's, and most of all had worked in the millitary bases near the demilitarized (DMZ). Thrombocytopenia and leukopenia were found more frequently by the laboratory findings. 23 of the cases(82%) were suspected to be malaria, before we confirmed it by peripheral blood smears.

Conclusion : The number of patients with indigenous malaria from the other areas in Korea and patients with malaria from foreign countries will be expected to increase. Before we confirmed the malaria by peripheral blood smears, the cases suspected of malaria were 82.1% This is a high diagnostic rate due to careful history taking and physical examination. The doctors decreased the rate of erroneous diagnosis of malaria and should be careful in the choice of the proper drugs.

Background
: Overt hyperthyroidism is a well-known cause of secondary hyperlipidemia and atherosclerosis. However, there have been some dissenting report of abnormalities and in serum lipid concentration in patients with subclinical hypothyroidism. We have attempted to analyze serum lipid concentrations to investigate whether they are increased in patients with subclinical hypothyroidism and to see if there is a correlation between serum LDL-C and TSH concentrations.

Methods : Serum lipid profiles(total cholesterol, triglycerides, LDL-C, HDL-C) of patients with subclinical hypothyroidism (M/F=7/119) compared with age, sex and body mass index matched control subject(M/F=14/239) from Jan. 1. 1996. to Dec. 30. 1997.

Results : There were no significant differences of serum total cholesterol, LDL cholesterol, TG, and HDL concentrations in 126 patients with subclinical hypothyroidism and 253 control subjects(178.47±35.76mg/Dl vs. 173.05±35.963mg/Dl ; 113.33±52.89mg/Dl vs.117.64±68.70mg/Dl ; 112.89±33.25mg/dL vs 109.65±29.02mg/Dl ; 48.60±11.34mg/Dl vs 46.51±11.73mg/Dl). There was no correlation between LDL cholesterol and TSH concentrations in subclinical hypothyroidism(r=0.29, p<0.05).

Conclusion : Serum lipid concentration(total cholesterol, LDL cholesterol, and TG, HDL) was not increased in patients with subclinical hypothyroidism. There was no correlation between serum LDL and TSH levels in patients with subclinical hypothyroidism.

Background
: The goals of this study are to evaluate the propensity to depression in Korean internet users associated wit internet using environment and attempt to aid proper management of internet users in the field of family practice.

Methods : A group of 1,674 subjects who replied to internet research were selected from March 26 to 28, 1999. Making use of CES-D-K for Korean internet users, we investigated t propensity to depression. At the same time, general characteristics, internet using environmental characteristics were investigated and their relationship was assessed.

Results : The CES-D-K score was 16.19. The CES-D-K score was significantly higher in females, in younger age and low education level group(P<0.001). There was no significance between CES-D-K score and region. In internet using environmental characteristics, the CES-D-K score was significantly higher in low velocity users, long internet using time per day group (P<0.001). There was no significance between CES-D-K score and internet using year.

Conclusion : There was a significant correlation between internet using velocity, internet using time per day and the propensity to depression. Therefore, family physician should think about the correlation of the propensity to depression and internet using environment, if internet users have symptoms of depression.

Background
: STDs are major communicable disease group in Korea. This study was carried out to evaluate the current status of sexually transmitted diseases in Seoul.

Methods : We collected the laboratory data of those who visited 11 Public Health Centers in Seoul for venereal disease examination and analyzed abnormal results from Jan 1, 1993 to Dec 31, 1995. The diagnoses of STDs were made by VDRL quantification, RPHA test, Gram's stain, and culture of urine or urethral discharge.

Results : There were total of 10,302 patients. There were 7,836 male cases(76.1%) and 2,466 female cases(23.9%). Mean age was 30.6±9.7, and the most common age group was 25-34 years of age(42.1%). Diagnoses were as follows ; syphilis 2,036 cases(19.8%), gonorrhea 2,249 cases(21.8%), nongonococcal urethritis 4,973 cases(48.3%), vaginitis 954 cases(9.3%), mixed infection of syphilis and gonorrhea 13 cases(0.1%), mixed infection of syphilis and NGU 50 cases(0.5%), mixed infection of syphilis and vaginitis 27 cases(0.3%). The proportion of PPNG among gonorrhea was as follows ; 43.4% in 1993, 55.1% in 1994, 43.8% in 1995. There were more WBCs on Gram's staining in gonorrhea cases than in NGU cases.

Conclusion : The STD patients seen in 11 Public Health Centers in Seoul were mainly young men. Common diagnoses were as follows ; NGU, gonorrhea, syphilis, vaginitis. The proportion of PPNG increased at first and then decreased.

Background
: Upper gastrointestinal bleeding is the most difficult problems at emergency status and early accurate diagnosis and prompt emergent care is needed because of variable etiology and high mortality. We studied comparatively about relationship between upper gastrointestinal bleedings and it's prognostic factors.

Methods : We analyzed 42 cases that upper gastrointestinal bleeding from on Feb. 1992 to on Jan 1993 at hospital setting.

Results : Among the 42 cases, the ratio of the male to the female is 2.8 to 1, more common in the male and the 3rd decade is the most common. For the etiologic cause, peptic ulcer is the most common as 19 cass. The character of the bleeding is mixed type of hematemesis and hematchezia to 45.2%. The predisposing factors are alcohol abuse and drug.

Conclusion : The significant risk factors are the evidence of associated disease, increased bleeding tendency, decreased hematocrit and increased BUN. We conclude that these patients must be treated with early, active management and therapy.

143 elderly who are staying in nursing home in Gyounggi-do are studied in terms of nutrional evaluation.
1. The proportion of smaller diet is higher in the age of 85 and more than any other age group.
2. The values of measurement of obesity index, BMI, and thickness of mid upperarm are significantly higher in female(P<0.50)
3. The prevalences of anemia according to hemoglobin level are 33.3% in men and 20.9% in female. However hemoglobin level less than 10.0g/dl are observed only in female.
4. Hypocalcemia are identified among 37.3% in male and 50% in female.
5. The levels of phosphorus are not significantly different in terms of age and sex.
6. hypoalbuminemia are identified among 17.6% in men and 27.2% in female.
This difference is statistically significant(P<0.05) and the level of albumin is inversely correlated with age.
7. means of cholesterol level are 184.7 mg/dl in female and 152.1mg/dl in men. The higher level in female may be related with the higher obesity rate.

Most primary care physicians are faced with continuous health care and this access is accomplished through the telephone because on-call arrangement is the traditional solution to patient care demands outside scheduled hours and provides a means by which the patient may interact with a health care provider at all times of day or night. For this purpose, we have given 24 hour telephone call service at Dept. of Family medicine, Seoul National University Hospital.
We analysed the contents of 108 calls for 5 months(90.5.1~9.30) from the family members who are registered in the same department in terms of age, sex, chief complaint and counselling.

Followings are the result of the study ;
1. A total of 108 calls were received during the study period and an average of 0.7 call day were received.
2. Of the patients who called, 61.8% was female and 38.2% was male.
3. According to patient's age, divided into age groups of 0-19, 20-29, 30-39, 40-49, 50-59 and 60-69year of age, the heighest number of patients were observed in age of 0-19 in male and in age of 30-49 in female.
4. When analysed by the type of caller, call from the patient was 51.4%, that from their relatives was 48.6%.
5. On weekdays, 76 calls were received and none on weekend, 32 calls were distributed throughout the day as follows;
40 calls(37.0%) were received by the physicians during daytime hours of 9AM to 3PM and 68 calls(63.0%) were received on after-hours.
6. The majority of the contents of calls were about the medical problems and diagnoses related to medical problems are recorded in the general categories of the international classification. The most common diagnoses are Gastrointestinal tract and Nervous and sense organ disease.
7. Most calls did not require a face to face visit as judged by the physician. So, of the calls, 44.8% were handled by the physicians with only information.

BACKGROUND
The students who had traveled in Jeju island developed symptoms of diarrhea at a girls' high school in Busan, June 2000. The goals of this study are to investigate the pattern of shigellosis and to compare drug resistance to S. sonnei with recent studies by reference reports.
METHODS
Through epidemiological investigation and stool test of new patients, 993 students were registered from Jun.12 to 17, 2000 in a girls' high school, Busan. 2nd grade students(N=355) who had traveled in Jeju island described a questionnaire of the source of infection. Clinical and bacteriological studies were carried out on 6 cases of patients with S. sonnei.
RESULTS
Among total 993 students, 79 patients were considered to have diarrhea. But 54 patients of 2nd grade students developed symptoms of diarrhea(14.7%) and the analysis of associative symptoms showed that it contained abdominal pain(72.2%), headache(61.6%), tenesmus(57.4%). 43 students of 2nd grade students who had traveled in Jeju ate chinese foods. Of them, 40 students showed diarrhea(93.0%) confirmed shigellosis(6 students), probable shigellosis(34 students). S. sonnei was isolated from 6 patients(14.0%). The attack rate of diarrhea was 20.7 times more in the group eating chinese foods than in the group not eating chinese foods(p<0.001). After the 2nd grade students ate chinese foods in Jeju, diarrhea attack day distribution was first day(23.2%), second day(39.7%), and third day(16.3%). The result of drug resistance test to S. sonnei(ampicillin, amoxicillin/clavulanic acid, tetracycline, sulfamethoxazole trimethoprim, and streptomycin) was 100%.
CONCLUSION
The 2nd grade patients with shigellosis ate chinese foods in a restaurant, Jeju. The pattern of antibiotic resistance to S. sonnei was different from that of several previous cases of shigellosis in Busan.