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"Yasuharu Tokuda"

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"Yasuharu Tokuda"

Original Article

Effect of Climate on COVID-19 Incidence: A Cross-Sectional Study in Japan
Mikiro Kato, Tomoko Sakihama, Yoshio Kinjo, David Itokazu, Yasuharu Tokuda
Korean J Fam Med 2022;43(1):37-41.   Published online January 20, 2022
DOI: https://doi.org/10.4082/kjfm.20.0260
Background
Effect of meteorological factors such as air temperature, humidity, and sunlight exposure on transmission dynamics of novel coronavirus disease 2019 (COVID-19) remains controversial. We investigated the association of these factors on COVID-19 incidence in Japan.
Methods
We analyzed data on reverse transcription polymerase chain reaction confirmed COVID-19 cases for each prefecture (total=47) in Japan and incidence rate was defined as the number of all reported cumulative cases from January 15 to March 17, 2020. Independent variables of each prefecture included three climatic variables (mean values of air temperature, relative humidity, and sunlight exposure), population elderly ratio, and the number of inbound travelers from China during February 2020. Multivariable-adjusted Poisson regression model was constructed to estimate COVID-19 incidence rate ratio (IRR) of independent variables.
Results
There was a total of 702 cases during the study period in Japan (population=125, 900,000). Mean±standard deviation values of meteorological variables were 7.12°C±2.91°C for air temperature, 67.49%±7.63% for relative humidity, and 46.77±12.55% for sunlight exposure. Poisson regression model adjusted for climate variables showed significant association between the incidence and three climatic variables: IRR for air temperature 0.854 (95% confidence interval [CI], 0.804–0.907; P<0.0001), relative humidity 0.904 (95% CI, 0.864–0.945; P<0.0001), and sunlight exposure 0.973 (95% CI, 0.951–0.997; P=0.026).
Conclusion
Higher values of air temperature, relative humidity and sunlight exposure were associated with lower incidence of COVID-19. Public health interventions against COVID-19 epidemic in a country should be developed by considering these meteorological factors.

Citations

Citations to this article as recorded by  
  • Effect of Long-Distance Domestic Travel Ban Policies in Japan on COVID-19 Outbreak Dynamics During Dominance of the Ancestral Strain: Ex Post Facto Retrospective Observation Study
    Junko Kurita, Yoshitaro Iwasaki
    Online Journal of Public Health Informatics.2024; 16: e44931.     CrossRef
  • Improvement of the software for modeling the dynamics of epidemics and developing a user-friendly interface
    Igor Nesteruk
    Infectious Disease Modelling.2023; 8(3): 806.     CrossRef
  • 3,501 View
  • 87 Download
  • 2 Web of Science
  • 2 Crossref

Review Article

Complexity of the Diagnosis of COVID-19 in the Context of Pandemicity: Need for Excellence in Diagnostic Acumen
Suresh K. Joishy, Michito Sadohara, Masaru Kurihara, Yasuharu Tokuda
Korean J Fam Med 2022;43(1):16-26.   Published online January 20, 2022
DOI: https://doi.org/10.4082/kjfm.20.0188
Coronavirus disease 2019 (COVID-19) is a highly infectious disease that has caused a pandemic devastating many countries worldwide. It is a complex and multifaceted disease with a unique coronavirus etiology, pathogenesis, zoonotic, and human-to-human transmission, causing acute respiratory distress syndrome with high mortality. Accurate and timely diagnosis is of utmost importance. In this study, we discussed the complexities of COVID-19 diagnostic elements in the context of pandemicity, drawing from our awareness, observations, and lessons learned from two previous coronavirus pandemics, namely SARS-CoV (severe acute respiratory syndrome coronavirus) in 2002 and MERS-CoV (Middle East respiratory syndrome-related coronavirus) in 2012, and how they applied to the diagnosis of COVID-19 today. Diagnosis of COVID-19 takes place without physician-patient personal contact due to isolation or quarantine or in the hospital setting, emergency units, and critical care units with the cumbersome barriers of personal protective equipment. Technical diagnosis is important, but we also emphasized the human impact of diagnosing COVID-19. Conveying the diagnosis of a critical disease to patients and families requires aspects of excellence in professionalism: ethics, empathy, and humility. Diagnostic skills in COVID-19 should extend to prognostication for patients suffering at the end of life, so that they will not be deprived of high-quality palliative care and comfort.

Citations

Citations to this article as recorded by  
  • Experience of caring for patients with COVID-19 and educational achievement among Japanese resident physicians: a nationwide survey with general medicine in-training examination
    Sho Nishiguchi, Yuji Nishizaki, Miki Hamaguchi, Atshushi Goto, Masahiko Inamori, Kiyoshi Shikino, Tomohiro Shinozaki, Koshi Kataoka, Taro Shimizu, Yu Yamamoto, Sho Fukui, Hiroyuki Kobayashi, Yasuharu Tokuda
    BMC Medical Education.2024;[Epub]     CrossRef
  • 5,777 View
  • 74 Download
  • 1 Web of Science
  • 1 Crossref
Case Report
Advanced Erosive Gout as a Cause of Fever of Unknown Origin
Mikiro Kato, Yuta Oishi, Makoto Inada, Yasuharu Tokuda
Korean J Fam Med 2015;36(3):146-149.   Published online May 22, 2015
DOI: https://doi.org/10.4082/kjfm.2015.36.3.146

A 61-year-old man was referred to our hospital due to a 3-month history of fever of unknown origin, and with right knee and ankle joint pains. At another hospital, extensive investigations had produced negative results, including multiple sterile cultures of blood and joint fluids, and negative autoantibodies. His serum uric acid level was not elevated. However, after admission to our hospital, we performed right knee arthrocentesis, which revealed uric acid crystals. These findings, combined with the results of imaging tests, which showed joint degeneration, led to a diagnosis of advanced erosive gout. After receiving a therapeutic non-steroidal anti-inflammatory drug and a maintenance dose of colchicine for prophylaxis against recurrence, the patient's symptoms subsided and did not return. Advanced erosive gout should be considered a possible cause of fever of unknown origin and diagnostic arthrocentesis should be performed in patients with unexplained arthritis.

Citations

Citations to this article as recorded by  
  • [Retracted] Clinical Features and Risk Factors of Fever in Acute Gouty Arthritis
    Yan Huang, Meiju Zhou, Fang Yuan, Zhijun Liao
    BioMed Research International.2022;[Epub]     CrossRef
  • Autopsing history: The mummy of Charlemagne (c. 747 – 814 AD), father of Europe
    Joachim H. Schleifring, Francesco M. Galassi, Michael E. Habicht, Frank J. Rühli
    Economics & Human Biology.2019; 32: 11.     CrossRef
  • Suppressive effect of Sanmiao formula on experimental gouty arthritis by inhibiting cartilage matrix degradation: An in vivo and in vitro study
    Fangfang Zhu, Lian Yin, Leilei Ji, Fan Yang, Guangji Zhang, Le Shi, Li Xu
    International Immunopharmacology.2016; 30: 36.     CrossRef
  • 3,823 View
  • 36 Download
  • 3 Web of Science
  • 3 Crossref
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