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"Yu Jin Paek"

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"Yu Jin Paek"

Original Articles

Differences in Factors Associated with Albuminuria according to Gender and Comorbidities of Hypertension and Diabetes
Miae Jang, Sohee Oh, Hye-Mi Noh, Sunyoung Chun, Hye young Oh, Kyung Hee Park, Yu Jin Paek, Hong Ji Song
Korean J Fam Med 2015;36(6):316-322.   Published online November 20, 2015
DOI: https://doi.org/10.4082/kjfm.2015.36.6.316
Background

This study examined the differences in factors associated with albuminuria according to gender and comorbidities of hypertension (HTN) and diabetes mellitus (DM).

Methods

We included 3,859 participants aged 20 to 79 years (55% female) from the 5th Korea National Health and Nutrition Examination Survey. Participants were excluded if they took antihypertensive or anti-diabetic medication, had chronic renal failure, had malignant tumor, were pregnant or menstruating during the health examination, or had missing urine albumin data. Albuminuria was defined by the participant's urine albumin-creatinine ratio (uACR). Relationships between dependent and independent variables were analyzed using the Pearson's correlation test and simple linear regression. Due to possible muticollinearity, multiple linear regression analysis was used to determine whether the association between the dependent and independent variables of interest remained significant after adjustment for other potentially confounding independent variables.

Results

The variables significantly correlated with uACR were different between the genders and between subjects with HTN or DM as a comorbidity. In the multiple linear regression models, hemoglobin A1c (P=0.01) was positively associated with uACR in men without HTN and DM. In men with HTN or DM, systolic blood pressure and fasting glucose (P<0.01) were positively associated with uACR. In women with HTN or DM, waist circumference (P=0.011) and gamma-glutamyl transpeptidase (P<0.001) were positively correlated with uACR (P<0.05) and glucose level (P=0.019) was negatively correlated with uACR.

Conclusion

The study suggested factors correlated with albuminuria were different for men and women according to comorbidities such as HTN and DM.

Citations

Citations to this article as recorded by  
  • Lifestyle Adherence and Metabolic Control in Adults with Type 2 Diabetes: Development of a Lifestyle Compliance Index
    Bianca-Lăcrimioara Petca, Paula-Alexandra Popovici, Andreea Diana Igna, Timea Claudia Ghitea, Mihaela Simona Popoviciu
    Diagnostics.2026; 16(18): 3068.     CrossRef
  • Sex-Specific Predictors of Microalbuminuria in Type 2 Diabetes: A Cross-Sectional Study
    Eun Sook Bae, Hye Seung Kang
    Korean Journal of Adult Nursing.2025; 37(3): 287.     CrossRef
  • High prevalence of albuminuria among adult males living with HIV in Botswana
    Mosepele Mosepele, Ponego Ponatshego, Kesaobaka Molebatsi, Christopher Williams, Lucky Mokgatlhe, Shahin Lockman, Nabila Youssouf, Robert Gross, Joseph Jarvis, Duolao Wang, Shabbar Jaffar
    Scientific Reports.2024;[Epub]     CrossRef
  • Relationship between serum and tear levels of tissue plasminogen activator and plasminogen activator inhibitor-1 in diabetic retinopathy
    Nurbadriah binti Jasmiad, Rohana binti Abd Ghani, Renu Agarwal, Zaliha binti Ismail, Azlindarita Aisyah Mohd Abdullah, Mohd Yusri Idorus
    BMC Ophthalmology.2022;[Epub]     CrossRef
  • Prevalence of micro albuminuria and diagnostic accuracy of urine dipstick for the screening of diabetic nephropathy in type 2 diabetes patients
    Sindhu Varghese, S. Gowtham Kumar
    Biocatalysis and Agricultural Biotechnology.2019; 21: 101316.     CrossRef
  • Differential Association of Vitamin D Deficiency With Albuminuria by Sex in the Korean General Population: A Cross-sectional Study of the Korea National Health and Nutrition Examination Survey 2011-2012
    Yongwoo Jeon, Jaeyong Shin, Jong Hyun Jhee, Youngdae Cho, Eun-Cheol Park
    Journal of Preventive Medicine and Public Health.2018; 51(2): 92.     CrossRef
  • 8,000 View
  • 26 Download
  • 4 Web of Science
  • 6 Crossref
Relationship between Brand Nicotine Yield of Cigarettes and Urine Cotinine Level in Male Smokers.
Sang Ho Yoon, Yu Jin Paek, Sang Ho Yoo, Jung Jin Cho, Hong Ji Song, Kyung Hee Park, Hye Mi Chang, Jin Hwa Ban
Korean J Fam Med 2009;30(9):703-709.   Published online September 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.9.703
Background
As one of harm reduction strategies, tobacco manufacturers have begun to introduce lower-yield cigarettes. Lower-yield cigarettes, so called light cigarettes, have been perceived as less hazardous by some smokers. However, there have been very few studies concerning smoking lower yield products the lead to lower nicotine absorption. We evaluated the association between brand nicotine yield of cigarettes and actual nicotine intake by measuring urinary cotinine. Methods: Four hundred sixty four male smokers aged 18 or over who participated in health check-ups in a hospital from May to October 2007 fi lled out a self-administered smoking questionnaire. Urinary cotinine concentration was measured at the time of participation. The subjects were divided into three groups (ultralight [nicotine: 0.05 mg], light [0.1 mg], and regular [> 0.1 mg] group) according to the level of brand nicotine yield of cigarettes which they smoked. Results: The median urinary cotinine concentrations of ultralight (N = 62), light (N = 216), and regular (N = 186) groups were 735.5 ng/mL (interquartile range, 320 to 1,300 ng/mL), 956.0 ng/mL (429 to 1,491 ng/mL), and 1,067.5 ng/mL (615 to 1,613 ng/mL), respectively. There was a signifi cant difference in urinary cotinine between the regular and the other groups (P = 0.015). However, multiple logistic regression analysis to evaluate the risk of being in the highest quartile of urinary cotinine concentration (≥ 1,532 ng/mL) after adjusting for possible confounding variables showed that the odds ratios were 0.84 (95% CI, 0.52 to 1.37) in the light nicotine group and 0.82 (95% CI, 0.38 to1.72) in the ultralight nicotine group compared to the regular nicotine group. Conclusion: There was no significant difference in the risk of elevated urinary cotinine concentrations in male adult smokers according to brand nicotine yield of cigarettes groups.
  • 2,957 View
  • 19 Download
Association between Depression and Cardiovascular Risk Factors in Workers Undergoing Comprehensive Medical Examination in a University-based Hospital.
Jong Won Choi, Jung Jin Cho, Hye Mi Chang, Chan Won Kim, Yu Jin Paek, Hong Ji Song, Kyung Hee Park, Whanseok Choi
J Korean Acad Fam Med 2008;29(9):645-650.   Published online September 10, 2008
Background: Depression increases the risk of cardiovascular risk factors in adults. However, the association between depression and cardiovascular risk factors was not well evaluated in South Korea. Our study was done to evaluate the association between depression and cardiovascular risk factors in workers. Methods: The study population was selected among adults working in several industries that had more than 50 employees. They had received their medical examinations at the Health Promotion Center of Hallym University Sacred Heart Hospital between March and November 2005. We estimated the odds ratio to determine whether depression (Korean Center for Epidemiologic Studies Depression Scale score ≥21) was associated with each cardiovascular risk factors (hypertension, diabetes mellitus, hypercholesterolemia, and obesity). Results: The prevalence of depression was 15.5%. Depression was significantly associated with hypertension (P<0.001), obesity (P=0.03) and hypercholesterolemia (P=0.004). The adjusted odds ratio for hypertension and hypercholesterolemia were 1.41 (95% CI 1.04∼1.91) and 1.59 (95% CI 1.05∼2.40), respectively. The association between depression and obesity was eliminated after adjustment (1.25, 95% CI: 0.97∼1.61). Conclusion: Depression was significantly associated with hypertension and hypercholesterolemia in workers. Further long-term study on the association of depression with cardiovascular risk factors is necessary. (J Korean Acad Fam Med 2008;29:645-650)
  • 2,360 View
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Percent Body Fat and Abdominal Circumference Cutoff Points Accounted for 85th and 95th Percentile of Body Mass Index in One City of Gyeonggi Province.
Chan Won Kim, Kyung Hee Park, Young Su Ju, Hong Ji Song, Yu Jin Paek, Jong Won Choi, He Mi Chang, Jung Jin Cho
J Korean Acad Fam Med 2008;29(7):492-498.   Published online July 10, 2008
Background: Childhood obesity is becoming more prevalent, associated with a variety of adverse consequences which leads to adulthood obesity. Although diagnosis is usually made by body mass index, there is neither a cutoff point for the percentage body fat nor abdominal circumference. The aim of this study was to identify each cutoff point for both measures. Methods: The measurement of height, weight, abdominal circumference and percentage body fat was performed through manual assessment and bioelectrical impedance analysis for 4,242 subjects aged 11 in Gunpo City, South Korea. The cutoff point for body fat percentage and abdominal circumference is set to maximize the sum of sensitivity and specificity for detecting obesity and overweight using the Receiver Operating Characteristics (ROC) curve. Results: The mean percentage body fat was 13.6±6.9% for boys and 19.4±5.3% for girls. The mean abdominal circumference of boys was 68.0±9.1 cm, and that of girls was 64.3±7.7 cm. The cutoff point of percentage body fat for obesity was 21.8% in boys and 24.5% in girls. The prevalence of obesity was 15.2%, 16.7% for males and females, respectively. The abdominal circumference cutoff for obesity was 76.9 cm in boys and 70.7cm in girls. Based on that, the prevalence of obesity was 19.7% for boys and 20.0% for girls, which was higher than what was identified by body mass index, as in the case of body fat percentage. Conclusion: The cutoffs of body fat percentage and abdominal circumference in one city of Gyeonggi Province were lower than those suggested in the previous studies. (J Korean Acad Fam Med 2008;29:492-498)
  • 2,189 View
  • 17 Download

Review

Psychometric Tools Related to the Assessment of Nicotine Dependence and Withdrawal Symptoms.
Myung Sig Kim, Yu Jin Paek
J Korean Acad Fam Med 2008;29(5):315-324.   Published online May 10, 2008
  • 2,052 View
  • 35 Download

Original Articles

The Relationship between Reduced Lung Function and High Sensitive C-reactive Protein in Healthy Adult Men.
Jung Un Lee, Yu Jin Paek
J Korean Acad Fam Med 2007;28(11):860-866.   Published online November 10, 2007
  • 1,904 View
  • 17 Download
The Current Educational Measurement of Family Practice Residents.
Min Jeong Kim, Ho Cheol Shin, Cheol Hawn Kim, Youn Seon Choi, Hang Lee, Ae Kyung Choi, Yu Jin Paek, Eon Sook Lee, Jin Ho Park, Yoon Jung Chang
J Korean Acad Fam Med 2007;28(8):616-625.   Published online August 10, 2007
Background
The educational assessment of residents is very important in order to check their knowledge and to improve their ability. In case of family practice, the residents spend most of their training time in outside rotations with other specialities. Therefore, they are requested to be evaluated by each specialist after each rotation. To give more accurate assessment, we surveyed directly our family practice residents and family practice faculties. Methods: A questionnaire was sent to family practice residents and family practice faculties in 116 hospitals from May to June 2006. The response rate was 29% and 78%, respectively. Results: Among the total, 70.2% of family practice residents thought an assessment is necessary, but only 51.7% were evaluated. Overall, 90.4% of family practice faculties knew about the assessment of residents made by other specialists, and only 56.7% of faculties requested other specialists to assess their family practice residents. Conclusion: Most of the family practice residents and their faculties knew the need for assessment, but they complained there were no objectivity and the assessment tool was lacking. In order to solve this problem, it is urgent to develop a unified form and guidelines of assesment. (J Korean Acad Fam Med 2007;28:616-625)
  • 1,969 View
  • 16 Download
Curriculum and Training Difficulties of Family Medicine Residency Programs in Korea.
Yu Jin Paek, Ho Cheol Shin, Cheol Hawn Kim, Youn Seon Choi, Hang Lee, Ae Kyung Cho, Eon Sook Lee, Jin Ho Park, Yoon Jung Chang, Min Jung Kim
J Korean Acad Fam Med 2007;28(5):367-374.   Published online May 10, 2007
Background
This study was conducted to survey the current status of family medicine residency programs and to evaluate the difficulties in training of the curriculums. Methods: Questionnaires on residency programs were sent to all the centers of residency programs by mail in April 2006. The questionnaire included detailed characteristics of residency programs, curriculum schedule, reasons for failed specific curriculum, and review and measures by the program center and the Korean Academy of Family Medicine to resolve problematic curriculums. Results: A total of 113 residency programs responded. Among the 93 residency programs except for the 20 subsidiary hospitals, inadeguate subjects were mainly dermatology (12 programs, 12.3%), psychiatry (6 programs, 7.5%), ophthalmology (5 programs, 7.1%), and otolaryngology (5 programs, 7.1%). Training rejection rate was higher in dermatology (13 programs, 14.4%), radiology (11 programs, 13.1%), gastrofibroscopy (8 programs, 9.5%), and psychiatry (5 programs, 6.2%). Emergency me-dicine in 4 programs and general surgery in 3 programs had a longer duration of training than initially planned. Difficulties in training some subjects were due to failed establishment of specific curriculums in non-university hospital. Commonly established clinics were health promotion center, obesity clinic, smoking cessation clinic, geriatric clinic, stress clinic, and clinical nutrition clinic. Family medicine center programs included gastrofibroscopy, obesity, smoking cessation, geriatrics, hospice care, and evidence-based medicine. Conclusion: There is repeated demand for taking measures to promote better curriculum in the nation-wide view of family medicine. Dermatology, radiology, psychiatry, and otolaryngology were the subjects difficult to receive training. Measures to strengthen the weak subjects are urgently needed. (J Korean Acad Fam Med 2007;28: 367-374)
  • 2,342 View
  • 23 Download
The Association between Gamma-glutamyltransferase and Metabolic Syndrome in Korean Male Workers.
Young Gyu Cho, Hong Ji Song, Hyung Jin Chung, Jung Jin Cho, Yu Jin Paek, Kyung Hee Park, Jung Soo Byun
J Korean Acad Fam Med 2007;28(1):45-50.   Published online January 10, 2007
Background
: Serum Gamma-glutamyltransferase (GGT) has been used clinically as a marker for excessive alcohol consumption or liver diseases, but it was reported recently that GGT is associated with cardiovascular disease. This study was done to verify the association between GGT and the metabolic syndrome in Korean male workers.

Methods : Total cholesterol, triglycerides, HDL cholesterol, body mass index (BMI), waist circumference, blood pressure, fasting glucose, uric acid, and GGT were measured and liver US was performed in 1,215 male workers who underwent annual health check up in a university health promotion center from May to October 2003. The association of GGT with the metabolic syndrome was assessed.

Results : The mean age of subjects was 41.9±7.2 years and the mean BMI was 24.1±2.7 kg/m2. A raised GGT level (GGT>75 IU/L) was seen in 172 of 1,136 (15.1%) and the prevalence of the metabolic syndrome was 9.9% (112/1,136). Individuals with the metabolic syndrome had a higher mean GGT concentration (53.4 IU/L) than individuals without the metabolic syndrome (34.4 IU/L; P<0.001). The subjects with increased GGT showed more risk of metabolic syndrome than the subjects with normal GGT by multivariate analysis (OR=2.835). Subgroup analyses did not change the association between the GGT and the metabolic syndrome.

Conclusion : This study showed that the serum GGT was associated with the metabolic syndrome and that increased GGT was another feature of the metabolic syndrome.
  • 2,020 View
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The Association between C-reactive Protein and Smoking Characteristics among Korean Men.
Joung Ki Choun, Yu Jin Paek, Jung Soo Byun, Kyung Hee Park, Hong Ji Song, Jung Jin Cho
J Korean Acad Fam Med 2005;26(10):621-628.   Published online October 10, 2005
Background
: C-reactive protein is a substance that elevates when there is an abnormal metabolic reaction or inflammatory condition. Some researchers in Korea reported different results about the association between smoking and CRP. In this study, the relationship between CRP and various smoking characteristics among Korean men was investigated.

Methods : Data were analyzed in healthy men, who had visited a health promotion center in a university hospital from September, 2003 to December, 2003. CRP was quantitatively analyzed by high sensitivity-CRP. Elevated CRP (≥2.2 mg/L) level in relation to various smoking characteristics were studied and multiple logistic regression analysis for elevated CRP (≥2.2 mg/L) level was conducted.

Results : The number of current smokers was 893, past smokers 550, and non-smokers 413. The association between smoking status, daily smoking amount, duration of smoking (P=0.031, P=0.003, P=0.034) and elevated CRP level was shown by chi-square test. After multiple logistic regression analysis for risk factors, elevated CRP level was shwon to be associated with daily smoking amount in the current smokers, body fat percentage, WBC count and HDL-cholesterol. The odds ratios for elevated CRP level by smoking amount were 2.32 (95% confidence interval 1.11∼4.85) in those who smoked 10∼19 cigarettes per day, 3.54 (95% confidence interval 1.64∼7.63) in those who smoked more than 20 cigarettes per day compared to those who smoked less than 10 cigarettes per day.

Conclusion : Among current smokers, elevated CRP level was associated with daily smoking amount in the current smokers, This is the first study to report the relationship between CRP level and smoking behaviors among Korean men.
  • 2,130 View
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Research and Scholarly Activity of Residency Programs of Family Medicine in Korea.
Sung Hee Lee, Yu Jin Paek, Soo Young Kim, Sang Woo Oh, Jae Yong Shim, Jung Kwon Lee
J Korean Acad Fam Med 2004;25(11):826-834.   Published online November 10, 2004
Background
: This study was conducted to survey current status of research and scholarly activity of residency programs and to evaluate quality of education.

Methods : Questionnaire on research and scholarly activity were sent to all residency training programs by regular mail on May 2003. The questionnaire included detailed characteristics of residency programs, current status of conferences, educations for research activities, degree of faculty involvement, and numbers of published papers and presentations for past year.

Results : A total of 103 residency programs answered the questionnaire. Most of the programs held journal review, book review, and clinical review in regular bases as scholarly activities. Smaller than 50% of the programs held case review, chart review, and psycho- social conference in regular bases. As research activity, 40 programs offered educations on epidemiology and statistics, and 55 programs held critical review of the literatures. Faculties involve actively in residents' research project in the process of designing research questions and selecting the subjects, but less actively in the process of gathering informations, completing manuscripts, and preparing presentations. Degrees of faculty involvement were smaller in the programs which are connected with medical school, had only 1 faculty, and educational experiences of the faculty were insufficient.

Conclusion : Current scholarly activities were active in various aspects, but psychosocial conference and chart audit should be encouraged. Special efforts are required in the research activities, especially in programs which were not connected with medical school and had only one faculty.
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A Selection and Translation of Evidence Based Clinical Practice Guidelines for Primary Care Physician in Respiratory Disease Field.
Soo Young Kim, Inhong Hwang, Jong Lull Yoon, Jung Jin Cho, Young Ho Choi, Yong Gyun Rho, Yoo Sun Moon, Mee Young Kim, Yu Jin Paek, Hong Ji Song, Kyung Hee Park
J Korean Acad Fam Med 2004;25(3):205-215.   Published online March 10, 2004
Background
: One method for achieving medical practice to be more evident, especially in the field of primary care, is to encourage the use of clinical guidelines. If development of guidelines is difficult because of time and cost, an evidence based foreign guidelines can be selected and translated into Korean for application.

Methods : A team was formed, consisting of 11 family physician experts on evidence based medicine and clinical practice guidelines. We selected six respiratory diseases requiring clinical guidelines because of variability in practice. We searched several clinical practice guideline databases and selected one guideline according to currency, scope of guideline, whether it was evidence based, and its feasibility in the field of primay care. We translated selected guideline's full-texts or summaries which were done by authorized organization into Korean.

Results : The selected respiratory diseases were chronic obstructive pulmonary disease, asthma, pneumonia, sinusitis, rhinitis, and influenza. According to criterion, we selected GOLD (Global Initiative for Chronic Obstructive Lung Disease) for chronic obstructive lung disease, GINA (Global initiative for asthma) for asthma, CDC (Center for disease control) guideline for influenza, IDSA (Infectious Diseases Society of America) guideline for pneumonia, AAP (American Academy of Pediatrics) guideline for sinusitis, and JCAAI (Joint Council of Allergy, Asthma and Immunology) for rhinitis.

Conclusion : We selected six common respiratory diseases and the most appropriate evidence based guidelines for those particular diseases.
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Attitude and knowledge of residents on domestic violence.
In Goo Lee, Yu Jin Paek, Min Su Park, In Sun Park
J Korean Acad Fam Med 2002;23(3):344-352.   Published online March 1, 2002
Background
: Nowadays there is an upsurge of, social concern on domestic violence. The role of doctors in the prevention and screening of domestic violence is becoming important. Therefore, we selected medical residents to find out about the attitude and knowledge of doctors on domestic violence.

Methods : From 2000 March to October, we surveyed questionnaires to residents. The contents included the attitude on the victims, assailants and the children of domestic violence, whether they had the will to report domestic violence to the police or not, and finally the knowledge about the law on domestic violence.

Results : Among 210 residents, 95 (45.2%) answered. Almost 90% of the subjects agreed to the necessity of social intervention on the assailants. And most residents agreed that the psychosocial impact of domestic violence to the exposed children was important. 65 (68.4%) residents said they would report to the police when they recognized victims of domestic violence during their consultation. 27-68% answered correctly about the law related to domestic violence. 40% agreed to the need of education for domestic violence.

Conclusion : The residents had little knowledge on domestic violence law. Therefore, it is essential for residents to be educated accordingly. The factors of marital status and sexual difference of doctors on domestic violence should be investigated.
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Parents' behavior related to the use of over -the - counter analgesics for elementary school children : focused in elementary school in Seoul.
In Goo Lee, Yu Jin Paek
J Korean Acad Fam Med 2002;23(2):179-188.   Published online February 1, 2002
Background
: Among the over-the-counter drugs, non-opioid analgesics are widely used in Korea. Non-opioid analgesics may have potential adverse effects such as side effects, tolerance, and addiction when used inappropriately. Moreover, children have less power to make a rational decisions than adults. Therefore, the role of parents in analgesic use is more and more important in children. This study was designed to investigate the frequency of use of analgesics in children and the behavior of parents administering them.

Methods : From April to May 2000, we collected questionnaires on the use of analgesics for relieving children's pain which were completed by parents from 3 elementary schools in Seoul. Student t-test and linear by linear test were applied to compare the difference between analgesic-administered group and non-administered group.

Results : The subjects were 630 parents among 702 respondents. Common reason for the parents to administer analgesics to their children were common cold, headache, abdominal pain etc. Pain severity were high in earache and fever and lower in abdominal pain and headache. Among the total 457(72.1%) parents were said to have kept analgesics at home. Acetaminophen and ibuprofen were the most common kept analgesics at home. Were more analgesic-keeping house likely to analgesics at home. Younger parents, younger children and mothers. Only 25.4% among those with analgesics at home gave analgesics during the last month. The administration rate was higher in the higher education levels(P<0.05), and increased linear by linear according to the number of house-keeping analgesics(P<0.05).

Conclusion : Seventy two percent of parents kept analgesics at home. But only a quarter of the parents gave analgesics to their children. The administration rate of analgesics in relieving pain in children by their parents was higher in the highly educated parents group and showed linear increase in proportion to the number of house-keeping analgesics.
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EAT score according to weight control, depression level and body mass index(BMI).
Yu Jin Paek, Hyun Eun Kang, Kang Eun Leem, Su Young Leem, Seung Ju Hwang, Tai Woo Yoo
J Korean Acad Fam Med 2001;22(5):690-697.   Published online May 1, 2001
Background
: It is reported that abnormal eating behavior is more frequent in the group of weight control than those of no control. Repeated and chronic binge eating behavior has associations with impaired work and social functioning. overconcerns with body shape and wight. The purpose of this study is to investigate the degree of abnormal eating behavior according to weight management, depression level and obesity.

Methods : From June 1999 to July 1999, we collected self-record questionnaire including body mass index(BMI), Back Depression Inventory(BDI), Eating Attitude Test(EAT), from 1292 students of one girl's high school in Seoul. Study subjects were divided by BMI, the set point was 25 ㎏/㎡. EAT score associated with weight control. BMI, BDI. smoking and alcohol was assessed by mul-tiple linear regression. Study subjects were also grouped by the existence of the history of weight management behavoir, then BMI, EAT score and BDI in each subgroups was assessed by t-test.

Results : Obese student were 42, whereas those of BMI under 25 ㎏/㎡ were 1191. BDI score ranging from 5 to 20 were 940, 21 to 63 were 179. The EAT score has significant relevance to the history of weight control, BMI, and BDI score in order. The EAT score and BMI were higher in the subjects who experienced various modes of weight control (48.41±14.47 vs 33.63±12.52 in EAT, 20.34±2.26 vs 18.72±1.89) (p<0.01).

Conclusion : EAT score was associated with weight control, BMI and BDI. EAT score and BMI were higher in weight control samples.
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The Clinical study for Efficacy and Safety of Amezinium methylsulfate.
Kang Eun Lim, Kwang Joon Jun, Hee Jeong Koh, Sung Kwon Hong, Yu Jin Paek, Taiwoo Yoo
J Korean Acad Fam Med 2000;21(7):914-921.   Published online July 1, 2000
Background
: Amezinium methylsulfate(Risumic) is the useful drug in the treatment of essential hypotension. This drug elevate blood pressure by stimulating sympathetic nervous system and improve symptoms related hypotension. This study was designed to evaluate efficacy and safety of Risumic for patients with essential hypotension.

Methods : This study was performed in patients with systolic blood pressure less than 100mmHg from June, 1999 to December, 1999. Risumic blood pressure response, improvement of symptom and side effect were examined in a double-blind, placebo-controlled, crossover trial.

Results : Total of 54 patients participated in this study and only 55.6% of them were finished and the rest of them(44.4%) was stopped. 6 patients of this patients were stopped because of side effects. But there was no difference in side effects in Risumic and placebo periods. In diastolic BP, Risumic group is 5mmHg higher than placebo group. And then there was significant difference in statistics.

Conclusion : In essential hypotensive patients, Risumic is elevater DBP than SBP, side effects frequency was no significant difference in Risumic and placebo group.
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Letter
No abstract available.
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