Korean Journal of Family Medicine

Fasting is not always good: perioperative fasting leads to pronounced ketone body production in patients treated with SGLT2 inhibitors: a case report: Jae Chan Choi, Yo Nam Jang, Jong Hoon Lee, Sang Wook Park, Jeong A Park, Hye Sook Kim, Jae Won Choi, Joo Hyung Lee, Yong Jae Lee; Korean J Fam Med 2025;46(3):204-209. Published online March 7, 2025; DOI: https://doi.org/10.4082/kjfm.24.0210

Abstract
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Ketone bodies produced by sodium-glucose cotransporter 2 (SGLT2) inhibitors can be advantageous, providing an efficient and stable energy source for the brain and muscles. However, in patients with diabetes, ketogenesis induced by SGLT2 inhibitors may be harmful, potentially resulting in severe diabetic ketoacidosis (DKA). During fasting, ketone body production serves as an alternative and efficient energy source for the brain by utilizing stored fat, promoting mental clarity, and reducing dependence on glucose. The concurrent use of SGLT2 inhibitors during perioperative fasting may further elevate the risk of euglycemic DKA. We describe a case of DKA that occurred during perioperative fasting in a patient receiving empagliflozin, an SGLT2 inhibitor. This case underscores the importance of recognizing the potential risk of DKA in patients with diabetes using SGLT2 inhibitors during perioperative fasting.

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A cross-sectional study of breakfast skipping and body composition among young adults: Esther Kim, Kyujin Choi, Su-Min Jeong, Hee-Kyung Joh; Received August 29, 2024 Accepted November 15, 2024 Published online February 26, 2025; DOI: https://doi.org/10.4082/kjfm.24.0217 [Epub ahead of print]

Abstract
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Background
Although breakfast provides essential nutrients and energy, skipping this meal has become increasingly common among young adults in Korea. In this study, we examine the relationship between breakfast consumption and body composition.
Methods
We analyzed data from 17,763 students aged 18–39 at Seoul National University (2018–2022). Participants were categorized based on their breakfast frequency: non-skippers, 1 to 3-day skippers, and 4 to 7-day skippers. Measurements included body mass index, waist circumference, body fat percentage, fat mass index (FMI), fat-free mass index (FFMI), and skeletal muscle mass index (SMI). Multivariable logistic and linear regression models adjusted for age, sex, alcohol use, smoking, physical activity, sleep, and food consumption frequencies were used.
Results
Obesity (17.4% vs. 14.8%) and abdominal obesity (10.0% vs. 7.8%) were higher in those skipping breakfast 4 to 7 d/wk compared with non-skippers. Skipping breakfast was not significantly associated with abdominal obesity in either sex. In women, the odds of obesity were higher (odds ratio, 1.57; 95% confidence interval, 1.14–2.15; P=0.006), whereas no significant difference was observed in men. Men who skipped breakfast had increased body fat percentage (coefficient, 0.87; P<0.001) and FMI (coefficient, 0.18; P=0.009) and decreased FFMI and SMI. Women showed increased body fat percentage (coefficient, 0.92; P<0.001) and FMI but no significant differences in FFMI or SMI.
Conclusion
Skipping breakfast adversely affects body composition by increasing body fat percentage and FMI. Further research is needed to confirm these findings and explore the underlying mechanisms.

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Cumulative circadian disruption factors and metabolic syndrome
Jungun Lee
Korean Journal of Family Medicine.2025; 46(3): 125. CrossRef

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Variables in the projection of physician demand and supply in primary care: Dae Hyun Kim, Yoonseo Lee; Korean J Fam Med 2025;46(1):4-11. Published online December 24, 2024; DOI: https://doi.org/10.4082/kjfm.24.0153

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Primary care services improve healthcare outcomes and limit unnecessary specialty care. Thus, it is essential to monitor primary care physician demand and supply projections to suggest evidence-based healthcare reforms and promote better healthcare delivery. This study evaluates 28 demand variables, 50 supply variables, and 26 additional variables associated with the demand and supply projections of physicians by reviewing scenarios from other countries, including Taiwan, Singapore, Japan, and the United States of America. The results indicate that Korea uses less diverse demand and supply indicators and suggest the need to implement variables used in the other four countries to improve projection modeling.

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What is the optimal number of physicians for a sustainable healthcare system?
Seung-Won Oh
Korean Journal of Family Medicine.2025; 46(1): 1. CrossRef

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Association between circadian rhythm-disturbing factors and metabolic syndrome in Korean adults: Korea National Health and Nutrition Examination Survey (2016–2020): Sujin Lee, Junhee Park, Hyunjin Cho, Jun Hyun Yoo; Korean J Fam Med 2025;46(3):162-169. Published online July 9, 2024; DOI: https://doi.org/10.4082/kjfm.23.0161

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Background
Circadian misalignment is associated with metabolic syndrome. This study aimed to examine the association between circadian rhythm-disturbing factors and metabolic syndrome.
Methods
We used data from the 7th and 8th Korea National Health and Nutrition Examination Survey conducted between 2016 and 2020, which surveyed 16,253 individuals. Circadian rhythm-disturbing factors were defined as follows: sleep duration outside the reference group (6–8 hours), irregular breakfast, shift work, and physical inactivity. The adjusted odds ratio (aOR) for metabolic syndrome was calculated based on the number of circadian rhythm-disturbing factors present in adults over the age of 19 years.
Results
Among a total of 16,253 participants (mean age 48.2±15 years), metabolic syndrome was found in 5,237 participants (29.3%). The participants were classified into three categories based on the number of circadian rhythm-disturbing factors as follows: 2,627 (15.6%) did not have any factors, 6,406 (38.13%) had one factor, and 7,220 (46.3%) had two or more factors. Participants with a single circadian rhythm-disturbing factor were 21% more likely to have metabolic syndrome (aOR, 1.21; 95% confidence interval [CI], 1.08–1.36), and participants with two or more factors were 27% more likely to have metabolic syndrome (aOR, 1.27; 95% CI, 1.12–1.43).
Conclusion
Circadian rhythm-disturbing factors were significantly associated with the prevalence of metabolic syndrome in Korean adults. This finding has potential clinical implications for maintaining circadian rhythms by avoiding certain factors to prevent metabolic syndrome. Further studies are required to confirm these findings.

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Cumulative circadian disruption factors and metabolic syndrome
Jungun Lee
Korean Journal of Family Medicine.2025; 46(3): 125. CrossRef

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Association between breakfast consumption frequency and chronic inflammation in Korean adult males: Korea National Health and Nutrition Examination Survey 2016–2018: Eun Ji Han, Eun Ju Park, Sae Rom Lee, Sang Yeoup Lee, Young Hye Cho, Young In Lee, Jung In Choi, Ryuk Jun Kwon, Soo Min Son, Yun Jin Kim, Jeong Gyu Lee, Yu Hyeon Yi, Young Jin Tak, Seung Hun Lee, Gyu Lee Kim, Young Jin Ra; Korean J Fam Med 2025;46(2):92-97. Published online July 5, 2024; DOI: https://doi.org/10.4082/kjfm.23.0151

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Background
Skipping breakfast is associated with an increased risk of chronic inflammatory diseases. This study aimed to examine the association between breakfast-eating habits and inflammation, using high-sensitivity C-reactive protein (hs-CRP) as a marker.
Methods
A total of 4,000 Korean adult males with no history of myocardial infarction, angina, stroke, diabetes, rheumatoid arthritis, cancer, or current smoking were included. Data from the 2016–2018 Korea National Health and Nutrition Examination Survey were used for analysis. The frequency of breakfast consumption was assessed through a questionnaire item in the dietary survey section asking participants about their weekly breakfast consumption routines over the past year. Participants were categorized into two groups, namely “0–2 breakfasts per week” and “3–7 breakfasts per week”; hs-CRP concentrations were measured through blood tests.
Results
Comparing between the “infrequent breakfast consumption (0–2 breakfasts per week)” and “frequent breakfast consumption (3–7 breakfasts per week)” groups, the mean hs-CRP was found to be significantly higher in the “infrequent breakfast consumption” group, even after adjusting for age, body mass index, physical activity, alcohol consumption, systolic blood pressure, blood pressure medication, fasting blood glucose, and triglycerides (mean hs-CRP: frequent breakfast consumption, 1.36±0.09 mg/L; infrequent breakfast consumption, 1.17±0.05 mg/L; P-value=0.036).
Conclusion
Less frequent breakfast consumption was associated with elevated hs-CRP levels. Further large-scale studies incorporating adjusted measures of daily eating patterns as well as food quality and quantity are required for a deeper understanding of the role of breakfast in the primary prevention of chronic inflammatory diseases.

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Cumulative circadian disruption factors and metabolic syndrome
Jungun Lee
Korean Journal of Family Medicine.2025; 46(3): 125. CrossRef

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Community Pharmacists’ Identifying and Counseling of Breastfeeding Women: A Study from Jordan: Mea’ad Mansour Harahsheh, Tareq Lewis Mukattash, Samah Fawzi Al-shatnawi, Rana Kamal Abu-Farha, Deirdre M. D’Arcy, Anan Sadeq Jarab, Sawsan Hammad Abuhammad; Korean J Fam Med 2024;45(6):346-355. Published online April 22, 2024; DOI: https://doi.org/10.4082/kjfm.23.0103

Abstract
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Background
This study explored the approaches of Jordanian community pharmacists to identifying and counseling breastfeeding mothers regarding medication usage.
Methods
This cross-sectional study used self-administered questionnaires. A convenience sample (n=381) of Jordanian community pharmacists was recruited through social media. The responses were statistically analyzed using IBM SPSS ver. 25.0 (IBM Corp., USA).
Results
The majority of recruited pharmacists were female (n=329, 86.4%). Asking every woman was Jordanian pharmacists’ preferred approach to identifying breastfeeding women (n=211, 55.4%). The study showed that around one-third of the pharmacists (n=128, 33.6%) reported that they currently experienced queries regarding medication use during breastfeeding on a daily basis. Additionally, the majority (n=325, 85.3%) of pharmacists reported feeling confident, and 67.2% of them (n=256) reported feeling comfortable while giving advice to breastfeeding women. The surveyed pharmacists relied on different resources during their course of practice to answer queries related to medicine usage by breastfeeding mothers.
Conclusion
Community pharmacists have continuous interactions with breastfeeding women. Pharmacists require reliable and updated data access to answer queries related to medication use while breastfeeding.

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Reflecting on progress and challenges: the Korean Journal of Family Medicine in 2024
Seung-Won Oh
Korean Journal of Family Medicine.2025; 46(2): 55. CrossRef

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Association between Chronic Atrophic Gastritis and Bone Mineral Density among Women Older than 40 Years of Age in Korea: Seulki Lee, Jae Moon Yun, Jin-Ho Park, Hyuktae Kwon; Korean J Fam Med 2024;45(4):199-206. Published online February 15, 2024; DOI: https://doi.org/10.4082/kjfm.22.0139

Abstract
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Background
Chronic atrophic gastritis causes hypochlorhydria, hypergastrinemia, and malabsorption of nutrients, leading to lower bone mineral density. The few studies that investigated the association between chronic atrophic gastritis and bone mineral density have reported inconsistent findings. As such, the present study assessed the association between chronic atrophic gastritis and bone mineral density among a large sample of women >40 years of age in Korea.
Methods
Data from 8,748 women >40 years of age who underwent esophagogastroduodenoscopy and bone densitometry were analyzed. Chronic atrophic gastritis was diagnosed using esophagogastroduodenoscopy. Bone mineral density of the lumbar vertebrae (L), femur neck, and femur total, measured using dual-energy X-ray absorptiometry, were the primary outcome variables. Low bone mineral density, which could be diagnosed as osteoporosis or osteopenia, was defined and analyzed as a secondary outcome. Linear regression was used to calculate adjusted mean values of bone mineral density. The association between low bone mineral density and chronic atrophic gastritis was analyzed using multiple logistic regression.
Results
The adjusted mean bone mineral density for L1–L4 was 1.063±0.003, femur neck (0.826±0.002), and femur total (0.890±0.002) were significantly lower in patients with chronic atrophic gastritis than others (1.073±0.002, 0.836±0.001, 0.898±0.002, respectively; all P<0.01). Women with chronic atrophic gastritis exhibited an increased likelihood for osteopenia or osteoporosis, even after adjusting for age and other confounding factors (odds ratio, 1.25; 95% confidence interval, 1.13–1.40; P<0.01). However, subgroup analysis revealed statistical significance only in postmenopausal women (odds ratio, 1.27; P<0.001).
Conclusion
Chronic atrophic gastritis was associated with lower bone mineral density and a higher risk for osteopenia or osteoporosis among postmenopausal women.

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Association between gastric polyps and decreased bone mineral density in patients with chronic gastritis
Guotao Liu, Jianyuan Zhang
Scientific Reports.2025;[Epub] CrossRef
The Interconnected Nature of Smoking, Depression, and Obesity in Behavioral Medicine
Joung Sik Son
Korean Journal of Family Medicine.2024; 45(4): 181. CrossRef

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Examining the Association between Cigarette Smoking Quantity and Subjective Salt Taste Preference and Salt-Related Eating Behavior: Jian Ma, Yeon-Kyung Lee; Korean J Fam Med 2023;44(6):335-341. Published online August 30, 2023; DOI: https://doi.org/10.4082/kjfm.23.0027

Abstract
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Background
Smoking can reduce taste sensitivity, the ability to sense various tastes, and diet quality and can increase the incidence of diseases such as hypertension. This study aimed to analyze the association between the smoking amount, subjective salt preference, and salt-related eating behaviors.
Methods
Data of more than 16 million individuals from the Korean Community Health Survey were used. Forest plots were drawn to compare the cumulative odds ratios of salt taste preference and salt-related eating behaviors, adjusted for sex, age, body mass index, education level, household income, marital status, and drinking status at various smoking levels.
Results
Subjective salt preference and salt-related eating behaviors increased with smoking amount; the adjusted odds ratios (AORs) for smoking >20 cigarettes were higher than those for smoking <20 cigarettes. For daily smokers, the AOR was 1.27 (95% confidence interval [CI], 1.22–1.31) for 1–5 cigarettes per day and 1.68 (95% CI, 1.65–1.71) for 16–20 cigarettes per day (P<0.001). Smokers were more likely to have more frequent salt-related eating behaviors than nonsmokers.
Conclusion
The subjective salt preference of smokers was higher than that of nonsmokers. Additionally, smokers used salt or soy sauce and dipped fried food in soy sauce more frequently than nonsmokers, which was also related to smoking amount.

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Risk-Reducing Measures for Cancer Prevention: Israel Oluwasegun Ayenigbara; Korean J Fam Med 2023;44(2):76-86. Published online March 20, 2023; DOI: https://doi.org/10.4082/kjfm.22.0167

Abstract
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Cancer, or malignancy, continues to be one of the most serious health problems in the world, leading to death and disability. Unlike in previous years, where new cases of cancer were predominant in developed nations, the number of cases of cancer and the resultant deaths are increasing in low- and middle-income countries. This is partially attributable to the current trend of adopting a Western lifestyle, substantial urbanization, and the rise in infections, such as the human papillomavirus (HPV) and hepatitis B virus (HBV), which together account for over 30% of cancer cases in underdeveloped and developing nations. The deleterious impact of cancer, as cases multiply worldwide, is multi-dimensional. Cancer exerts serious physical, psychological, and monetary burdens, not only on cancer patients but also on their family members, close friends, health care systems, and society at large. Importantly, over half of all cancer types can be prevented globally by mitigating the risk and causative factors as well as prompt adherence to scientifically recommended prevention measures. This review provides various scientifically based and people-centered strategies that every individual could adopt to reduce their risk of developing cancer in the future. It is recommended that, for these cancer prevention strategies to be effective, there should be a strong political will from the governments of individual countries to enact specific laws and implement policies that will significantly reduce sedentary lifestyles and unhealthy eating among the general public. Likewise, HPV and HBV vaccines, as well as cancer screenings, should be made available, affordable, and accessible on a timely basis for those who are eligible to take them. Finally, intensified campaigns and numerous informative and educational programs that promote cancer prevention should be initiated globally.

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Vegan Diet: A Novel Trend in Healthy Living
Gaithaongamliu Kamei, Prasad Rasane, Jyoti Singh, Sawinder Kaur, Mahendra Gunjal, Jaspreet Kaur, Raghav Gupta, Dipendra Kumar Mahato, Sushma Gurumayum, Sunil Kumar Dwivedi
Current Nutrition & Food Science.2024; 20(8): 952. CrossRef
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Sagnik Nag, Adrija Bhunia, Sourav Mohanto, Mohammed Gulzar Ahmed, Vetriselvan Subramaniyan
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Muhammad Majid, Abdul Qayoom, Ali Haider
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Muhammad Majid, Abdul Qayoom, Ali Haider
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Application of Machine Learning and Deep Learning Models in Prostate Cancer Diagnosis Using Medical Images: A Systematic Review
Olusola Olabanjo, Ashiribo Wusu, Mauton Asokere, Oseni Afisi, Basheerat Okugbesan, Olufemi Olabanjo, Olusegun Folorunso, Manuel Mazzara
Analytics.2023; 2(3): 708. CrossRef

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Split Tummy Exercise Program for Reducing Diastasis Recti in Postpartum Primigravidae: A Randomized Controlled Trial: Suhaila Shohaimi, Nik Rosmawati Nik Husain, Faizah Mohd. Zaki, Ixora Kamisan Atan; Korean J Fam Med 2023;44(2):102-108. Published online March 20, 2023; DOI: https://doi.org/10.4082/kjfm.22.0035

Background
Diastasis rectus abdominis (DRA) involves the separation of the midline abdominal muscles and linea alba and affects more than half of postpartum women. This study aimed to assess the effect of a split tummy exercise program (STEP) on DRA closure in postpartum mothers.
Methods
A randomized controlled trial was conducted from 2008 to 2020 at the Obstetrics and Gynaecology Clinic of the Universiti Kebangsaan Malaysia Medical Centre. Primigravida mothers diagnosed with DRA were selected and randomly assigned to the intervention (n=21) or control (n=20) group. The intervention group underwent a home-based STEP consisting of three phases of nine abdominal exercises. DRA size was assessed at baseline and at 8 weeks postpartum using two-dimensional ultrasound.
Results
The mean age of the participants was 28 years (standard deviation, 3.6), with the majority of Malay ethnicity (87.8%) and working mothers (78%). After 8 weeks, the intervention group showed a significant reduction in DRA size of up to 27% (mean difference, 6.17 mm; 95% confidence interval, 3.7–8.7; P<0.001). No significant intergroup DRA changes were observed after 8 weeks of follow-up.
Conclusion
Early postpartum screening for DRA should be advocated to allow early STEP intervention to ensure favorable outcomes. STEP intervention is an effective postnatal training program for managing DRA.

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Impact of postpartum exercise on pelvic floor disorders and diastasis recti abdominis: a systematic review and meta-analysis
Nicole F Beamish, Margie H Davenport, Muhammad Usman Ali, Matthew J Gervais, Talia Noel Sjwed, Gyanjot Bains, Allison Sivak, Rita E Deering, Stephanie-May Ruchat
British Journal of Sports Medicine.2025; 59(8): 562. CrossRef
Comparative Efficacy and Acceptability of Non-surgical Treatments with or without Exercise for Diastasis Recti Abdominis in Postpartum Women: A Network Meta-Analysis of Randomized Controlled Trials
Wen-Chieh Wu, Wen-Hong Wu, Ming-Fen Lee, Pei-Yu Wu, Yu-Kang Tu, Hsuan Lin, Chien-Yi Chan, Chun-Yin Huang
Sports Medicine.2025; 55(4): 937. CrossRef
Comparative Efficacy of Abdominal Exercises and Abdominal Binding on Diastasis Recti Abdominis Reduction in Postpartum Women: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Abdullah, Khawaja Abdul Rehman, Bilal Ahmad, Muhammad Khubaib Arshad, Humza Saeed, Mahnoor Asghar Keen, Amna Anwar, Noor ul ain Saleem, Umm E. Salma Shabbar Banatwala, Zara Bilal, Maryam Shahzad, Pakeeza Shakoor, Muhammad Ahsen Niazi
Physiotherapy Research International.2025;[Epub] CrossRef
Recomendaciones médicas desde atención primaria sobre ejercicio físico en el posparto
L.M. Gallo-Galán, M.A. Gallo-Vallejo, J.L. Gallo-Vallejo
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Intra‐ and Interimage Reliability of Inter‐Rectus Distance Measurements Determined via Ultrasound Imaging by the Same or Different Testers in Women in the Early Postpartum Period
Qing Jiang, Ya Gao, Shuyu Xia, Yuefan Gu, Jun Gu, Jianfeng Guo, Guannan Feng, Qifeng Deng, Xuedong Deng
Journal of Ultrasound in Medicine.2024; 43(6): 1037. CrossRef
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Ana Clara Moreira de Jesus, Andresa Santos Souza, Gabrielle Barreto Menezes, Jisielle Oliveira dos Santos, Luiz André Santos Silva, Elisama de Campos Guimarães, Isabela da Silva Vasconcelos Rodrigues, Grace Kelly Melo de Almeida
Revista Contemporânea.2024; 4(7): e5102. CrossRef
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Ujala Afzal, Quratulain Saeed, Muhammad Nabeel Anwar, Sanna Pervaiz, Manahil Shahid, Rimsha Javed, Muhammad Umair Ali, Seung Won Lee
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Mercedes Soto-González, Iria Da Cuña-Carrera, Eva María Lantarón-Caeiro, Augusto Gil Pascoal, Shabnam ShahAli
PLOS ONE.2024; 19(12): e0314274. CrossRef

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Written Asthma Action Plan Improves Asthma Control and the Quality of Life among Pediatric Asthma Patients in Malaysia: A Randomized Control Trial: Juliawati Muhammad, Najwa Diyana Ngah, Imran Ahmad; Korean J Fam Med 2023;44(1):44-52. Published online January 19, 2023; DOI: https://doi.org/10.4082/kjfm.22.0016

Abstract
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Background
A written asthma action plan (WAAP) is one of the treatment strategies to achieve good asthma control in children.
Methods
This randomized controlled trial was conducted to observe the effect of WAAP on asthma control and quality of life using the Asthma Control Questionnaire and Pediatric Asthma Quality of Life Questionnaire (PAQLQ) at baseline and after 3 months. A repeated measure analysis of variance was used to analyze the mean score difference between the two groups.
Results
There was no significant difference in mean score for asthma control at baseline between groups (F[degree of freedom (df)]=1.17 [1, 119], P=0.282). However, at 3 months, a significant difference in mean scores between groups was observed (F[df]=7.32 [1, 119], P=0.008). The mean±standard deviation (SD) scores in the intervention and control groups were 0.96±0.53 and 1.21±0.49, respectively. For the analysis of the PAQLQ, no significant difference was observed in the mean score for the quality of life baseline in both groups. There were significant mean score changes for the quality of life (F[df]=10.9 [1, 119], P=0.001) at 3 months follow-up, where those in the intervention group scored a mean±SD score of 6.19±0.45, and those in the control group scored 5.94±0.38. A time-group interaction analysis using repeated-measures analysis of variance showed significant differences in mean score changes (F[df]=5.03 [1, 116], P=0.027) and (F[df]=11.55 [1, 116], P=0.001) where a lower mean score was observed in the intervention group, indicating better asthma control and quality of life, respectively. A significant (P<0.001) negative Pearson correlation between asthma control and quality of life (-0.65) indicated a moderate correlation.
Conclusion
WAAP, along with standard asthma treatment, improves asthma care.

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Accessibility of health and preventive care for patients with bronchial asthma
L.Yu. Nikitina, O.S. Mishina, V.V. Gainitdinova, T.Yu. Gneusheva, O.V. Nagatkina, R.M. Aynetdinov, G.V. Lukyanova, I.A. Bogdanov, I.A. Deev, S.N. Avdeev
Journal of Respiratory Medicine.2025; 1(1): 15. CrossRef
The impact of asthma education grounded in virtual reality technology upon the quality of life of pediatric patients with bronchial asthma
Huijuan Wang, Qing Dong, Xiaowei Wang
Frontiers in Pediatrics.2025;[Epub] CrossRef
The utility of the necessity-concerns framework (NCF) in explaining adherence and parental beliefs about controller medication in Saudi Arabian children with asthma
Marja A. Alyami, Mohammed M. Alyami, Ahmed H Alasimi, Jaber S. Alqahtani, Abdullah A. Alqarni, Abdulelah M. Aldhahir
Journal of Asthma.2024; 61(5): 436. CrossRef

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Association between Serum Folic Acid Levels and Asthma in the Korean Population: A Study Based on the 2016–2018 Korea National Health and Nutrition Examination Survey: So Ra Kim, Eun Ju Park, Young Hye Cho, Sang Yeoup Lee, Jung-In Choi, Young-In Lee, Sae Rom Lee, Yun Jin Kim, Jeong Gyu Lee, Yu Hyeon Yi, Young Jin Tak, Seung Hun Lee, Gyu Lee Kim, Young Jin Ra; Korean J Fam Med 2022;43(4):241-245. Published online July 19, 2022; DOI: https://doi.org/10.4082/kjfm.21.0143

Abstract
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Background
Folic acid is involved in inflammatory reactions; however, the association between folic acid and allergic diseases, particularly asthma, remains unclear. Thus, this study aimed to evaluate the association between serum folic acid levels and asthma in Koreans.
Methods
This study analyzed the serum folic acid levels of 6,615 individuals included in the 2016–2018 Korea National Health and Nutrition Examination Survey. The prevalence of asthma was determined using a questionnaire that identified cases of physician-diagnosed asthma. The relationship between serum folic acid levels and asthma was analyzed using logistic regression analysis.
Results
Multiple logistic regression analysis showed that a 1 ng/mL increase in serum folic acid level significantly reduced the risk of asthma after adjusting for confounding factors including sex, age, household income, current smoking, current alcohol use, and body mass index (odds ratio [OR], 0.930; 95% confidence interval [CI], 0.876– 0.987; P=0.017). The relationship between the adjusted odds of asthma and serum folic acid levels were consistently inverse (OR, 2.266; 95% CI, 1.126–4.420; P for trend=0.038).
Conclusion
Serum folic acid levels are inversely associated with physician-diagnosed asthma in the Korean population.

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Association between serum folate levels and blood eosinophil counts in American adults with asthma: Results from NHANES 2011–2018
Jun Wen, Changfen Wang, Mohan Giri, Shuliang Guo
Frontiers in Immunology.2023;[Epub] CrossRef

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Association between Complementary and Alternative Medicine Use and Fear of Cancer Recurrence among Breast Cancer Survivors: Esther Eun Hwa Kim, Jihun Kang; Korean J Fam Med 2022;43(2):132-140. Published online March 17, 2022; DOI: https://doi.org/10.4082/kjfm.20.0158

Abstract
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Background
This study aimed to evaluate the association between complementary and alternative medicine (CAM) use and fear of cancer recurrence (FCR) among breast cancer survivors, using a validated multidimensional FCR-assessing instrument. Despite the debate over its medical effects, the use of CAM in breast cancer survivors is increasing.
Methods
We recruited 326 breast cancer survivors who had completed the primary cancer treatment. Information on CAM use was obtained using a self-administered questionnaire, and FCR was assessed using the Korean version of the FCR Inventory (FCRI). Multivariate linear regression analysis was performed to evaluate the association between CAM use and FCR.
Results
CAM users had higher total FCR scores than CAM non-users after covariate adjustment (CAM users: 74.6 vs. CAM non-users: 68.7; P=0.047). Among the FCRI subscales, CAM users showed higher coping strategy scores (CAM users: 22.3 vs. CAM non-users: 20.6; P=0.034) in the multivariable adjusted analysis. The use of multiple types of CAM was associated with increased FCR in a dose-dependent manner (P=0.002).
Conclusion
Breast cancer survivors who used CAM had a higher FCR than CAM non-users. The dose-response relationship between the use of multiple types of CAM and FCR suggests that breast cancer survivors who use multiple types of CAM should be provided with appropriate psychological interventions to decrease FCR.

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Critical Considerations Regarding the Article “Association between Complementary and Alternative Medicine Use and Fear of Cancer Recurrence among Breast Cancer Survivors”
Niloufar Johari Varnoosfaderani, Ehsan Amiri-Ardekani
Korean Journal of Family Medicine.2023; 44(1): 66. CrossRef
Use of complementary and alternative medicine for reducing fear of cancer recurrence among cancer survivors: Does it work?
Heliang Wu, Adnan Rashid Aziz, Mahlagha Dehghan, Leyla Ahmadi Lari, Rasmieh Al-Amer, Mohammad Ali Zakeri
Asia-Pacific Journal of Oncology Nursing.2023; 10(10): 100278. CrossRef
Adherence to lifestyle recommendations among Norwegian cancer survivors and the impact of traditional and complementary medicine use: the Tromsø Study 2015–2016
Kiwumulo Nakandi, Faith O. Benebo, Laila A. Hopstock, Trine Stub, Agnete E. Kristoffersen
BMC Complementary Medicine and Therapies.2023;[Epub] CrossRef

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Effects of Galohgor Nutraceutical Lactation Cookies on Breast Milk Volume and Lactose Concentration: Katrin Roosita, Bahriyatul Ma’rifah, Naufal Muharam Nurdin, Faisal Anwar; Korean J Fam Med 2022;43(1):56-62. Published online January 20, 2022; DOI: https://doi.org/10.4082/kjfm.20.0224

Abstract
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Background
Galohgor nutraceutical lactation cookies (NLC) contain polyherbal which is believed and consumed by postpartum mothers of Sundanese Ethnic in Indonesia to increase breast milk production. This study was aimed to analyze the effects of NLC cookies on breast milk volume and lactose concentrations of postpartum mothers.
Methods
The experimental study with post-controlled design was conducted. Twenty eligible mother-infant pairs were enrolled and divided into two groups. They were randomly assigned to receive NLC (n=9) or original cookies (ORC, n=11). Each subjects consumed 4 pieces/d of NLC which containing 1 g galohgor nutraceutical powder/ pieces or ORC (without galohgor nutraceutical powder), for 14 days intervention period since the first day of giving birth. The measurement of breast milk production was carried out by baby weighing method using SECA 334 digital baby scale (SECA, Hamburg, Germany). A high-performance liquid chromatography method was used to determine lactose concentrations in breast milk. Data were analyzed by parametric Independent T-test or the nonparametric Mann-Whitney U-test and adjusted analysis of covariance.
Results
NLC significantly increased (P<0.05) breast milk production, as shown by average breast milk volume of NLC compared to ORC, i.e., 557.0 (95% confidence interval [CI], 497.3–616.6) mL/d vs. 435.9 (95% CI, 382.3–489.6) mL/d. This result was supported by lactose concentration in breast milk of mothers who consumed NLC significantly higher (P<0.05), compared to ORC, i.e., 6.03% (95% CI, 5.66%–6.40%) vs. 5.18% (95% CI, 4.85%–5.51%).
Conclusion
NLC which containing galohgor nutraceutical can be recommended to increase breast milk volume and lactose concentration in the early postpartum period.

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Effectiveness of lactation cookies on human milk production rates: a randomized controlled trial
Ana M. Palacios, Michelle I. Cardel, Erik Parker, Stephanie Dickinson, Valerie R. Houin, Bridget Young, David B. Allison
The American Journal of Clinical Nutrition.2023; 117(5): 1035. CrossRef

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Complexity of the Diagnosis of COVID-19 in the Context of Pandemicity: Need for Excellence in Diagnostic Acumen: Suresh K. Joishy, Michito Sadohara, Masaru Kurihara, Yasuharu Tokuda; Korean J Fam Med 2022;43(1):16-26. Published online January 20, 2022; DOI: https://doi.org/10.4082/kjfm.20.0188

Abstract
PDF

Coronavirus disease 2019 (COVID-19) is a highly infectious disease that has caused a pandemic devastating many countries worldwide. It is a complex and multifaceted disease with a unique coronavirus etiology, pathogenesis, zoonotic, and human-to-human transmission, causing acute respiratory distress syndrome with high mortality. Accurate and timely diagnosis is of utmost importance. In this study, we discussed the complexities of COVID-19 diagnostic elements in the context of pandemicity, drawing from our awareness, observations, and lessons learned from two previous coronavirus pandemics, namely SARS-CoV (severe acute respiratory syndrome coronavirus) in 2002 and MERS-CoV (Middle East respiratory syndrome-related coronavirus) in 2012, and how they applied to the diagnosis of COVID-19 today. Diagnosis of COVID-19 takes place without physician-patient personal contact due to isolation or quarantine or in the hospital setting, emergency units, and critical care units with the cumbersome barriers of personal protective equipment. Technical diagnosis is important, but we also emphasized the human impact of diagnosing COVID-19. Conveying the diagnosis of a critical disease to patients and families requires aspects of excellence in professionalism: ethics, empathy, and humility. Diagnostic skills in COVID-19 should extend to prognostication for patients suffering at the end of life, so that they will not be deprived of high-quality palliative care and comfort.

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Experience of caring for patients with COVID-19 and educational achievement among Japanese resident physicians: a nationwide survey with general medicine in-training examination
Sho Nishiguchi, Yuji Nishizaki, Miki Hamaguchi, Atshushi Goto, Masahiko Inamori, Kiyoshi Shikino, Tomohiro Shinozaki, Koshi Kataoka, Taro Shimizu, Yu Yamamoto, Sho Fukui, Hiroyuki Kobayashi, Yasuharu Tokuda
BMC Medical Education.2024;[Epub] CrossRef

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Metoclopramide for Milk Production in Lactating Women: A Systematic Review and Meta-Analysis: Nik Hazlina Nik Hussain, Norhayati Mohd Noor, Shaiful Bahari Ismail, Nur Amirah Zainuddin, Zaharah Sulaiman; Korean J Fam Med 2021;42(6):453-463. Published online November 20, 2021; DOI: https://doi.org/10.4082/kjfm.20.0238

Abstract
PDF

Background
Breastfeeding is recognized as the optimal form of nutrition for the physical and neurological development of infants and is considered the most significant way to prevent child mortality. This study aimed to assess the effectiveness of metoclopramide for enhancing milk production in lactating women.
Methods
We searched the Cochrane Central Register of Controlled Trials and MEDLINE for randomized controlled trials comparing metoclopramide with a placebo, no treatment, or other galactagogue drugs. We included breastfeeding women with term or preterm infants.
Results
We retrieved 164 records from our search of the electronic databases and 20 records from other sources. Eight trials involving 342 lactating women that used metoclopramide were included in this review after assessing the eligibility criteria. The meta-analysis of these trials revealed that metoclopramide did not increase the milk volume of the intervention groups compared to that of the control groups. There was a significant increase in the serum concentrations of prolactin when the mothers were administered metoclopramide. No significant adverse events were reported.
Conclusion
Metoclopramide did not improve milk production in lactating women. Therefore, we do not recommend using metoclopramide to increase milk production in lactating women.

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Saurabh Maru, Sateesh Belemkar
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Consenso académico de prácticas de impacto de la lactancia en Colombia
Nancy Bernal, Carlos Timossi, Maria Mercedes Pulido, Maria Isabel Uscher, Luz Stella Hidalgo, Carolina Gómez, María Emilia Contreras
Pediatría.2025; 57(3): e574. CrossRef
Clinical evaluation of Ayush-SS granules in exclusively breastfeeding mothers with insufficient lactation: A randomized, double-blind, placebo-controlled trial
Upma Saxena, Sarada Ota, Shivshankar Rajput, Bhavna Anand, Arunabh Tripathi, Richa Singhal, Adarsh Kumar, Abhishek Lachyan
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Inducing Lactation in a Transgender Woman Without Galactagogues: A Case Report
Baila Elkin, Alisa Duran, Kevin Rauwerdink, Elizabeth S. Goldsmith
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Safety of pharmacologically induced lactation
Patrick L. Thøgersen, Ditte R. Gotfredsen, Christina Gade, Henrik Horwitz, Jon T. Andersen
Adverse Drug Reaction Bulletin.2023; 341(1): 1323. CrossRef

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Exclusive Breastfeeding Practice in Indonesia: A Population-Based Study: Maria Gayatri; Korean J Fam Med 2021;42(5):395-402. Published online September 20, 2021; DOI: https://doi.org/10.4082/kjfm.20.0131

Abstract
PDF

Background
It is a well-known fact that exclusive breastfeeding benefits both mothers and their babies. The aim of this study is to assess the associated factors influencing exclusive breastfeeding of babies until 6 months of age.
Methods
The study used data from the 2017 Indonesia Demographic and Health Survey. Overall, 1,542 women who had infants aged below 6 months were included in the study. Sociodemographic and maternal health service utilization factors were examined for association with exclusive breastfeeding, using logistic regression for a complex sample design.
Results
The proportion of exclusive breastfeeding was 52.3% (95% confidence interval [CI], 0.498–0.548). Parity, antenatal care visits, early initiation of breastfeeding, low-income households, and rural areas were significant factors associated with the increased likelihood of exclusive breastfeeding. However, working status (adjusted odds ratio [aOR], 0.70; 95% CI, 0.57–0.86) and caesarean delivery or C-section (aOR, 0.75; 95% CI, 0.57–0.99) were factors for a lower likelihood of exclusive breastfeeding.
Conclusion
Working women are at risk of discontinuation of exclusive breastfeeding. Mothers who had a normal vaginal delivery and practiced early initiation of breastfeeding had a higher rate of exclusive breastfeeding. These findings have important implications for developing comprehensive guidance and resources for women regarding the importance of exclusive breastfeeding during the early postpartum period.

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Laili Rahayuwati, Desy Indra Yani, Sri Hendrawati, Arlette Suzy Setiawan, Damar Irza, Sherllina Rizqi Fauziah
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Economic and environmental impacts of commercial milk formula in Indonesia: estimates and comparisons using the Cost of Not Breastfeeding, Green Feeding, and Mothers’ Milk Tools
Nabila Nur Septiani, Andini Pramono, Tuan Thanh Nguyen, Roger Mathisen, Julie Smith
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Educational Packages on Breastfeeding Increase Behavior and Self-Efficacy of Mothers
Stefi Maizuputri, Muthia Mutmainnah, Meinarisa
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Role of proper postnatal care in continued exclusive breastfeeding among young Indonesian mothers
Wahyu Triadmajani, Shinta Prawitasari, Abdul Wahab
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Does caesarean section have an impact on exclusive breastfeeding? Evidence from four Southeast Asian countries
Kyaw Lwin Show, Nampet Jampathong, Pyae Linn Aung, Kyawt Mon Win, Chetta Ngamjarus, Porjai Pattanittum, Thae Maung Maung, Khaing Nwe Tin, Su Mon Myat, Meghan A Bohren, Nogati Chairunnisa, Pisake Lumbiganon
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The practice of exclusive breastfeeding by region in Indonesia
Haerawati Idris, Dea Widya Astari
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Social media utilization and knowledge levels in exclusive breastfeeding among mothers in Indonesia
Deswani Deswani, Dea Eki Rahmawati, Yuli Mulyanti, Syafdewiyani Syafdewiyani, Rita Ismail, Sri Djuwitaningsih
Healthcare in Low-resource Settings.2023;[Epub] CrossRef
Analysis of Supporting Factors Associated with Exclusive Breastfeeding Practice in the Urban Setting during the COVID-19 Pandemic
Agrina Agrina, Dedi Afandi, Suyanto Suyanto, Erika Erika, Yulia Irvani Dewi, Siska Helina, Dita Pramita, Nanda Safira
Children.2022; 9(7): 1074. CrossRef

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The Association between Serum Vitamin D Concentration and Colon Polyp: A Cross-Sectional Study Using Health Care Screening Database in a Tertiary Hospital in Korea: Mun Young Yoo, Jungkwon Lee, Ji In Chung, Yohwan Yeo, In Young Cho; Korean J Fam Med 2021;42(4):303-309. Published online July 20, 2021; DOI: https://doi.org/10.4082/kjfm.20.0181

Background
As indoor activity increases with modern lifestyles changes, reduced exposure to sunlight may lead to reduced vitamin D synthesis. Previous studies demonstrated that increased vitamin D level is associated with decreased risk of colon cancer; therefore, this study attempted to determine the association between vitamin D and colon polyps, which may be precancerous lesions, in participants who underwent colonoscopy exams.
Methods
A total of 31,004 participants who underwent routine health checkups, including vitamin D level and colonoscopy, at Samsung Medical Center in South Korea from 2010 to 2018 were included in the study. Colorectal polyps were diagnosed through biopsy after performing colonoscopy exams. Participants were categorized into three groups according to level of vitamin D (deficient: <20 ng/mL), insufficient: 20≤ vitamin D <30 ng/mL, and sufficient: ≥30 ng/mL). We analyzed the presence of colorectal polyps according to vitamin D level, and performed multiple logistic regression analyses for the association between vitamin D level and colorectal polyps.
Results
About 50% of participants had colorectal polyps (hyperplastic polyp, n=4,864; adenomatous polyp, n=10,470; adenocarcinoma, n=24). There were no significant associations between vitamin D categories and colorectal polyp and colorectal cancer. However, when further analyzing by type of polyp, the risk of hyperplastic polyps significantly decreased with increasing vitamin D levels (P for trend=0.006).
Conclusion
We did not find evidence for an association between vitamin D and overall colorectal polyps; however, we observed a trend for decreased odds of hyperplastic polyps with increased vitamin D levels in comparison to vitamin D deficient subjects.

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Siyao Lv, Yunyi Ding, Junli Huang, Yixin He, Ruijie Xie, Xiaohong Shi, Wei Ye
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Exploring Vitamin D Deficiency and IGF Axis Dynamics in Colorectal Adenomas
George Ciulei, Olga Hilda Orășan, Angela Cozma, Vasile Negrean, Teodora Gabriela Alexescu, Simina Țărmure, Florin Eugen Casoinic, Roxana Liana Lucaciu, Adriana Corina Hangan, Lucia Maria Procopciuc
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Seung-Kwon Myung, Heram Cho
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Association of 25(OH)-Vitamin D and metabolic factors with colorectal polyps
Chih-Hsiang Chiang, Yu-Jun Chang, Sin-Ru He, Jih-Ning Chao, Chih-Huai Yang, Yen-Tze Liu, Yavuz - Ayar
PLOS ONE.2023; 18(6): e0286654. CrossRef
Research Progress on Risk Factors and Protective Factors of Colorectal Adenomatous Polyps
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Zhixin Zhu, Xifei Guan, Nawen Liu, Xiaoxia Zhu, Sheng Dai, Dehai Xiong, Xiuyang Li
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Effect of Education on Promoting Healthy Lifestyle Behaviors That Prevent Breast Cancer in Middle-Aged Women: Application of Protection Motivation Theory: Zakieh Sadat Hoseini, Hamid Tavakoli Ghouchani, Hamidreza Mohaddes Hakak, Hossein Lashkardoost, Ali Mehri, Mehdi Khankolabi, Elahe Salari; Korean J Fam Med 2021;42(2):166-171. Published online June 29, 2020; DOI: https://doi.org/10.4082/kjfm.19.0164

Abstract
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Background
In recent years, an increased incidence of breast cancer has made this disease the most common malignancy among Iranian women. Since education plays an important role in the implementation of preventive behaviors in breast cancer treatment, this study investigates the effect of educational interventions on the promotion of lifestyle-related behaviors that prevent breast cancer in middle-aged women.
Methods
In this randomized control study, 120 women referred to Neyshabur Health Services Centers were randomly selected and divided into two groups: an intervention group (60 subjects) and a control group (60 subjects). An educational intervention was carried out over five sessions, based on protective motivation theory constructs. Participants completed a researcher-designed questionnaire immediately and again 2 months after the intervention. The data were analyzed using IBM SPSS ver. 19.0 software (IBM Corp., Armonk, NY, USA).
Results
The results revealed a significant difference between the mean scores of participants exposed to protective motivation theory, awareness, and physical activities immediately and also 2 months after the intervention (P<0.05). Although the healthy diet scores of the two groups differed significantly immediately after the educational intervention (P<0.05), there was no significant difference between the groups 2 months after the intervention (P<0.05).
Conclusion
Given the effective role of education in protective motivation theory and the physical activity levels of the women who participated in this research, it seems clear that the women’s financial status shaped their ability to consume more fruits and vegetables. As this social element impacts the health of individuals, training programs alone cannot succeed.

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The effect of educational intervention based on protection motivation theory in improving reproductive health protective behaviors: a quasi-experimental study
Zahra Japalaghi, Asieh Bahrami, Reza Beiranvand, Hossein Soltaninejad, Mahdieh Varseh, Nader Sharifi
BMC Women's Health.2025;[Epub] CrossRef
Increasing Knowledge about Breast Cancer in Young Women with Word Square Model Education
Putri Nofia Marta Wulandari, Sri Wahyuni Adriani, Siti Kholifah
Advances in Cancer Science.2024; 1(1): 8. CrossRef
Explaining information seeking intentions: Insights from a Slovenian social engineering awareness campaign
Simon Vrhovec, Igor Bernik, Blaž Markelj
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The effect of self-care training programs on lifestyle and breast self-examination of immigrant Afghan women
Elaha Jafari, Mahnaz Zarshenas, Monireh Toosi, Azar Nematollahi, Mehrab Sayadi
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Protection Motivation Theory and Prevention of Breast Cancer: A Systematic Review
Fatemeh Estebsari, Zahra Rahimi Khalifehkandi, Marzieh Latifi, Abdollah Farhadinasab, Parvaneh Vasli, Davoud Mostafaie
Clinical Breast Cancer.2023; 23(4): e239. CrossRef
Predictors of breast self‐examination behavior among adult females in Najran city, Saudi Arabia
Awad M. Al‐Qahtani, Heba A. Ibrahim, Wafaa T. Elgzar
Japan Journal of Nursing Science.2022;[Epub] CrossRef

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Healthy Beliefs regarding Breast Cancer Screening in Iranian Women Health Volunteers: A Path Analysis: Fatemeh Salmani, Mitra Moodi, Azam Yousefi, Ensiyeh Norozi; Korean J Fam Med 2021;42(2):132-139. Published online May 28, 2020; DOI: https://doi.org/10.4082/kjfm.20.0001

Abstract
PDF

Background
In Iran, 82% of breast cancer cases are diagnosed in late stages, resulting in low survival rates. In the present study, the Stages of Change Theory and Health Belief Model were used as theoretical frameworks for assessing Women Health Volunteer readiness to act on different breast cancer screening behaviors.
Methods
A total of 1,410 Women Health Volunteers were enrolled in this cross-sectional study. The breast self-examination (BSE) and mammography stages of change were measured independently. A standardized questionnaire based on the Health Belief Model was used to assess their beliefs about breast cancer screening methods. A path analysis using PASW SPSS ver. 18.0 (SPSS Inc., Chicago, IL, USA) was used to test the effects of individual beliefs on breast cancer screening stages of change.
Results
Most participants were classified in the pre-contemplation stage of breast cancer screening behaviors. Perceived barriers, benefits, and susceptibility emerged as BSE stages of change predictors. No beliefs were significant mammography stages of change predictors.
Conclusion
Iranian Women Health Volunteers had a very low adherence to common BSE and mammography practices. Healthy beliefs have a strong association with the stages of change for performing BSE, but not for mammography. The impact of health beliefs on an individual’s readiness to act on different breast cancer screening methods may vary with respect to the type of screening method.

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SAĞLIĞIN SOSYAL BELİRLEYİCİLERİNİN MEME KANSERİ BİLGİ DÜZEYİ VE TARAMALARINA ETKİSİ: BİR SİSTEMATİK DERLEME
Özlem Durmuş, Keziban Avcı
Eskişehir Türk Dünyası Uygulama ve Araştırma Merkezi Halk Sağlığı Dergisi.2025; 10(2): 246. CrossRef

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Factors Associated with Early Breastfeeding Initiation among Women Who Underwent Cesarean Delivery at Tertiary Hospitals in Kelantan, Malaysia: Nazirah Johar, Noraini Mohamad, Norkhafizah Saddki, Tengku Alina Tengku Ismail, Zaharah Sulaiman; Korean J Fam Med 2021;42(2):140-149. Published online May 19, 2020; DOI: https://doi.org/10.4082/kjfm.19.0178

Abstract
PDF

Background
Cesarean delivery is linked with lower rates of early breastfeeding initiation. This study aimed to determine the prevalence and associated factors of early initiation of breastfeeding among women admitted for elective cesarean delivery in Kelantan, Malaysia.
Methods
A total of 171 women admitted for elective cesarean delivery at two tertiary hospitals in Kelantan, Malaysia, participated in this study. On day two after cesarean delivery, face-to-face interviews were conducted with the mothers to get information on feeding practice. Descriptive statistics, including simple and multiple logistic regressions, were used for data analysis.
Results
Seventy-three percent of mothers initiated breastfeeding within 1 hour of birth. Approximately 15.8% and 10.5% of mothers initiated breastfeeding within 24 hours and ≥24 hours, respectively. Skin-to-skin contact between mothers and their infants occurred in 77.8% of cases after cesarean delivery. Breastfeeding initiation was significantly associated with skin-to-skin contact (odds ratio [OR], 14.42; 95% confidence interval [CI], 3.58–58.06), mothers who exclusively breastfed during hospitalization (OR, 36.37; 95% CI, 5.60–236.24), and infants who were not sleepy during attempts at breastfeeding (OR, 5.17; 95% CI, 1.32–20.21).
Conclusion
Based on our results, it is possible to increase the proportion of mothers initiating breastfeeding within 1 hour among women who undergo elective cesarean delivery. Therefore, it is important that health practitioners educate women beginning in the antenatal period who plan to undergo cesarean delivery by emphasizing the importance of early initiation of breastfeeding.

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Prevalence of Delayed Initiation of Breastfeeding and Its Associated Factors Among Mothers Who Gave Birth by Cesarean Section in Gamo and Gofa Zones, Southern Ethiopia: A Multicenter Cross‐Sectional Study
Arega Abebe Lonsako, Tsehaynew Kasse, Aster Dure, Abera Cheru, Kinde Kibe, Addisalem Haile, Roxana Valdés-Ramos
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Hyun Kyoung Lee, Eunwook Joo, Seongbeen Kim, Iseop Cho, Kyong-No Lee, Hyeon Ji Kim, Bohyoung Kim, Jee Yoon Park
Journal of Human Lactation.2023; 39(1): 59. CrossRef
Timely initiation of breastfeeding among women who gave birth by cesarean section in central Ethiopia, 2022: A cross-sectional study
Arega Abebe Lonsako, Haymanot Mezmur, Arsema Gebreyesus, Gadissa Tolosa, Sagni Girma, Abera Mersha
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C Cirpanli, B Demirtas Hicyilmaz
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Richard Gyan Aboagye, Joshua Okyere, Robert Kokou Dowou, Leticia Akua Adzigbli, Vivian Tackie, Bright Opoku Ahinkorah, Abdul-Aziz Seidu
BMJ Open.2022; 12(9): e062422. CrossRef
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Nor Hazirah Amalina Che Hussain, HuiJun Chih, Syahrul Bariah Abdul Hamid
Malaysian Journal of Medicine and Health Sciences.2022; 18(s15): 72. CrossRef
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Rejina Gurung, Avinash K. Sunny, Prajwal Paudel, Pratiksha Bhattarai, Omkar Basnet, Srijana Sharma, Durgalaxmi Shrestha, Seema Sharma, Honey Malla, Dela Singh, Sangeeta Mishra, Ashish KC
International Breastfeeding Journal.2021;[Epub] CrossRef

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Unsuccessful Exclusive Breastfeeding and Associated Factors among the Healthcare Providers in East Coast, Malaysia: Saodah Hashim, Azlina Ishak, Juliawati Muhammad; Korean J Fam Med 2020;41(6):416-421. Published online January 14, 2020; DOI: https://doi.org/10.4082/kjfm.19.0060

Abstract
PDF

Background
Breastfeeding is widely recognized as the optimal and natural method of feeding infants. However, there are obstacles that can limit exclusive breastfeeding practices during the first 6 months of an infant’s life. This study aimed to determine the prevalence of unsuccessful exclusive breastfeeding and its associated factors among mothers who work as healthcare providers at Universiti Sains Malaysia Hospital.
Methods
A cross-sectional study was conducted among 295 medical doctors and staff nurses from June to December 2015. Simple random sampling was applied. The data were collected using a self-administered questionnaire and analyzed using IBM SPSS ver. 22.0 (IBM Corp., Armonk, NY, USA). Descriptive statistics and logistic regression analysis were performed.
Results
The prevalence of unsuccessful exclusive breastfeeding among the study participants was 58.3%. Mothers who preferred formula milk (odds ratio [OR], 4.40; 95% confidence interval [CI], 1.45–13.31) delivered via lower segment cesarean section (OR, 2.31; 95% CI, 1.07–4.98) and produced inadequate breast milk (OR, 4.06; 95% CI, 2.40– 6.89) were significantly associated with unsuccessful exclusive breastfeeding.
Conclusion
The prevalence of unsuccessful exclusive breastfeeding among the study participants was high. Maternal characteristics such as preference towards formula milk, mode of delivery and adequacy of breast milk must be assessed to prevent unsuccessful exclusive breastfeeding among healthcare providers.

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Febri Adriati, Rizka Dita Hidayati
Jurnal Midpro.2025; 16(2): 203. CrossRef
Enhancing maternal role achievement and breastfeeding success through health belief model intervention
Nurus Safaah, Esti Yunitasari, Budi Prasetyo, Mira Triharini, Pipit Feriani
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The practice of exclusive breastfeeding by region in Indonesia
Haerawati Idris, Dea Widya Astari
Public Health.2023; 217: 181. CrossRef
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Bewuketu Terefe, Kegnie Shitu
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Exclusive Breastfeeding in Health Personnel: Incidence and Barriers
Tongta Nanthakomon, Sonthaya Nukaw, Sudatip Kositamongkol
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Exclusive Breastfeeding Practice in Indonesia: A Population-Based Study
Maria Gayatri
Korean Journal of Family Medicine.2021; 42(5): 395. CrossRef
On the Relationship between Social Support and Early Breastfeeding Termination
Marzieh Faghani Aghoozi, Mohaddeseh Karimi Khoshal, Sanaz Faiazi, Shahnaz Tork Zahrani, Malihe Amerian
Preventive Care In Nursing and Midwifery Journal.2019; 9(1): 1. CrossRef

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Perceived Barriers to Mammography Adoption among Women in Iran: A Qualitative Study: Shayesteh Shirzadi, Hamid Allahverdipour, Manoj Sharma, Hadi Hasankhani; Korean J Fam Med 2020;41(1):20-27. Published online February 26, 2019; DOI: https://doi.org/10.4082/kjfm.18.0054

Abstract
PDF

Background
Breast cancer is the most commonly diagnosed tumorous cancer and the second leading cause of cancer-related deaths among women worldwide. This study aimed to qualitatively explore the barriers to mammography adoption among Iranian women.
Methods
This study is a qualitative component of a large research project on exploratory sequential mixed method design, utilizing conventional content analysis. In total, 24 participants were selected from among women who had participated in the first phase of the study. Data were collected through in-depth, semi-structured interviews.
Results
Five main themes were extracted, consisting of unawareness of mammography, fear control, priority of mammography needs, inadequate competency of mammography centers, and a sense of losing family support.
Conclusion
Different perceived barriers within various levels (individual, intrapersonal, health systems, and community) play influential roles in women’s decisions to participate in breast cancer screening program, which indicates the cultural aspect of perceived barriers in different communities and countries. The study provides the basis for intervention planning in this regard.

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Behind the Screen: An Exploratory Study of Factors Influencing Breast Screening Uptake in Lancashire (UK)
Yik Nok Bryan Lee, Alexander Montasem, Lauren Haworth, Jonathan Sinclair, Kim McGuire, Ambreen Chohan
Health Expectations.2025;[Epub] CrossRef
Anxiety Levels Among Women Undergoing Mammogram Screening
Wedad M. Almutairi, Salwa Hassan Alzahrani
Current Oncology.2025; 32(3): 160. CrossRef
Development and validation of the psychometric properties of the perceived barriers of mammography scale
Shayesteh Shirzadi, Mohammad Asghari-Jafarabadi, Mahnaz M. Harrison, Hamid Allahverdipour
Health Care for Women International.2024; 45(6): 621. CrossRef
Overcoming obstacles to mammography screening: Examining the role of offline healthcare barriers and online patient–provider communication
Yuyuan Kylie Lai, Jizhou Francis Ye, Song Harris Ao, Xinshu Zhao
Journal of Health Psychology.2024; 29(5): 452. CrossRef
Exploring the practice of Iranian adolescent females during menstruation and related beliefs: a qualitative study
Mojgan Mirghafourvand, Abbas Ebadi, Shayesteh Jahanfar, Fatemeh Khorashadizadeh, Shayesteh Shirzadi
BMC Public Health.2024;[Epub] CrossRef
Risk perception regarding social determinants of health among women with breast cancer in Iran: a qualitative study
Arezou Ashari, Neda SoleimanvandiAzar, Marzieh Nojomi, Hadi Ranjbar, Kamran Mirzaei, Nahid Nafissi, Mahshid Roohravan Benis, Zahra Rampisheh
BMJ Open.2024; 14(8): e081839. CrossRef
Need assessment for the content of educational programs about breast cancer from the viewpoint of unaffected women
Sadaf Alipour, Marzieh Orouji, Yas Eskandari, Amirhossein Eskandari
BMC Women's Health.2023;[Epub] CrossRef
Acceptability and compliance with a breast cancer prevention campaign in the Northwest Region, Iran
Saeed Dastgiri, Geertruida H de Bock, Zohreh Sanaat, Mahnaz Ranjkesh, Zhila Abbasi, Pooneh Jabbaripour, Shima Pashaie, Soheila Poorsaberi, Roya Dolatkhah
Breast Cancer Management.2022;[Epub] CrossRef
Qualitative factors influencing breast and cervical cancer screening in women: A scoping review
Jerrald Lau, Pami Shrestha, Janelle Shaina Ng, Gretel Jianlin Wong, Helena Legido-Quigley, Ker-Kan Tan
Preventive Medicine Reports.2022; 27: 101816. CrossRef
Factors Associated with Screening Mammogram Uptake among Women Attending an Urban University Primary Care Clinic in Malaysia
Nasturah Abdullah, Noorhida Baharudin, Mariam Mohamad, Mohamed-Syarif Mohamed-Yassin
International Journal of Environmental Research and Public Health.2022; 19(10): 6103. CrossRef
Breast Cancer in Asia: Incidence, Mortality, Early Detection, Mammography Programs, and Risk-Based Screening Initiatives
Yu Xian Lim, Zi Lin Lim, Peh Joo Ho, Jingmei Li
Cancers.2022; 14(17): 4218. CrossRef
Barriers to women’s breast cancer screening behaviors in several countries: A meta-synthesis study
İlknur Özkan, Seçil Taylan
Health Care for Women International.2021; 42(7-9): 1013. CrossRef
Beliefs, fear and awareness of women about breast cancer: Effects on mammography screening practices
Lida Emami, Akram Ghahramanian, Azad Rahmani, Ahmad Mirza Aghazadeh, Tonia C. Onyeka, Amirreza Nabighadim
Nursing Open.2021; 8(2): 890. CrossRef
A systematic review of decision aids for mammography screening: Focus on outcomes and characteristics
Marzieh Esmaeili, Seyed Mohammad Ayyoubzadeh, Zohreh Javanmard, Sharareh R. Niakan Kalhori
International Journal of Medical Informatics.2021; 149: 104406. CrossRef
Breast cancer screening behavior and its associated factors in female employees in South Khorasan
Zoya Tahergorabi, Mahyar Mohammadifard, Fatemeh Salmani, Mitra Moodi
Journal of Education and Health Promotion.2021; 10(1): 102. CrossRef
Fear of negative appearance evaluation and attitude towards mammography: Moderating role of internal health locus of control,cancer worry and age
Saeed Pahlevan Sharif, Ashraf Sadat Ahadzadeh, Fon Sim Ong, Navaz Naghavi
Health Promotion Perspectives.2020; 10(3): 220. CrossRef
Factors affecting mammography screening behaviour among rural Vietnamese women
Linh Thuy Duong, Hui‐Mei Chen, Chieh‐Yu Liu, Piao‐Yi Chiou
European Journal of Cancer Care.2020;[Epub] CrossRef
Perceived Barriers and Awareness of Mammography Screening Among Saudi Women Attending Primary Health Centers

Doaa M Abdel-Salam, Rehab A Mohamed, Hind Y Alyousef, Wahaj A Almasoud, Mashael B Alanzi, Atheer Z Mubarak, Doaa M Osman
Risk Management and Healthcare Policy.2020; Volume 13: 2553. CrossRef

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Knowledge, Attitude, Exposure, and Future Intentions toward Exclusive Breastfeeding among Universiti Sains Malaysia Final Year Medical and Dental Students: Noraini Mohamad, Norkhafizah Saddki, Khairun Nadzirah Khairul Azman, Ida Dahlia Ab Aziz; Korean J Fam Med 2019;40(4):261-268. Published online January 9, 2019; DOI: https://doi.org/10.4082/kjfm.18.0021

Abstract
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Background
Breastmilk is the best nourishment for an infant for the first 6 months of life. Health professionals like medical doctors and dentists can help promote and support exclusive breastfeeding. We aimed to assess knowledge, attitudes, exposure, and future intentions toward exclusive breastfeeding among final year medical and dental students at Universiti Sains Malaysia, Kelantan, Malaysia.
Methods
A total of 162 students participated in this cross-sectional study that was conducted between May and September of 2015. Self-administered questionnaires were used to collect the variables of interest.
Results
Most students knew exclusive breastfeeding is recommended for the first 6 months of life (98.1%). However, some students incorrectly thought formula milk can be given if the infant appears hungry after having been breastfed (61.7%). Additionally, some incorrectly thought expressed breastmilk can be warmed on direct heat (47.5%) and left-over expressed milk can be re-stored (60.5%). Most students agreed that exclusive breastfeeding is easier to practice than formula feeding and that it is the best choice for working mothers. Most students (93.2%) intend to breastfeed their children, and this intention was significantly associated with their experience being breastfed as infants and attitudes toward exclusive breastfeeding.
Conclusion
Generally, final year medical and dental students have favorable attitudes and future intentions toward exclusive breastfeeding, although some of them lacked knowledge about certain important aspects of the practice. Past experience of being exclusively breastfed and a more positive attitude toward the practice were associated with their future intentions to practice exclusive breastfeeding.

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CONHECIMENTO DOS ESTUDANTES DE MEDICINA SOBRE ALEITAMENTO MATERNO
Jasmin Januth Vieira, Anna Clara Piccin Henriques De Souza, Joyce de Freitas Souza, Ester Queiroz Galavotti, Wanêssa Lacerda Poton
REVISTA FOCO.2023; 16(4): e1690. CrossRef
Conocimiento y actitudes sobre los beneficios de la lactancia materna en universitarios
Juan Alejandro Hernández-Pérez, Miguel Ángel Hernández-Hernández, María de los Ángeles Ramírez-Trujillo
CienciaUAT.2021; : 42. CrossRef

27,946 View
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Associations of Breastfeeding Duration and Reproductive Factors with Sarcopenia in Elderly Korean Women: A Cross-Sectional Study from the Korea National Health and Nutrition Examination Survey 2010–2011: Ja-Young Kim, Do-Hyoung Kim, Young-Hyo Kim, Hyun-Young Shin; Korean J Fam Med 2019;40(3):165-170. Published online January 7, 2019; DOI: https://doi.org/10.4082/kjfm.17.0084

Abstract
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Background
Several studies have suggested that breastfeeding has a positive effect on long-term obesity, diabetes, hypertension, and hyperlipidemia. This study aimed to examine maternal bone health, muscle mass, and obesity based on breastfeeding duration.
Methods
This study was based on the Korea National Health and Nutrition Examination Survey 2010–2011. We selected 2,027 elderly women by screening survey participants with a history of delivery. Multivariate logistic regression analyses were performed to estimate the odds ratios (ORs) of sarcopenia, osteoporosis, and obesity among four breastfeeding groups.
Results
The OR of sarcopenia significantly decreased with increasing breastfeeding duration (OR, 0.27; 95% confidence interval [CI], 0.11–0.65; P for trend <0.001), whereas the OR of obesity significantly increased with increasing breastfeeding duration (OR, 2.56; 95% CI, 1.43–4.60; P for trend=0.009) after adjusting for potential confounding variables. We also found a positive correlation between the duration since last delivery and sarcopenia.
Conclusion
Our results suggest a negative correlation between prolonged breastfeeding and the prevalence of sarcopenia, and a positive correlation between prolonged breastfeeding and the prevalence of obesity. Further studies are needed to clarify the relationship between breastfeeding and sarcopenia in the future.

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Interventions and Programs to Promote Breastfeeding in Arabic-Speaking Countries: A Scoping Review
Basil H. Aboul-Enein, Elizabeth Dodge, Nada Benajiba, Ruth M. Mabry
Maternal and Child Health Journal.2023; 27(5): 774. CrossRef
Breastfeeding Duration Is Associated with the Risk of Tooth Loss, Chewing Difficulty, and Undernutrition among Older Korean Women: Results of the Korea National Health and Nutrition Examination Survey (KNHANES) 2013–2015
Ye Rang Jo, Yoo Kyoung Park, Hee-Sook Lim
Nutrients.2023; 15(24): 5024. CrossRef
Association of total lifetime breastfeeding duration with midlife handgrip strength: findings from Project Viva
Irasema C. Paster, Pi-i D. Lin, Sheryl L. Rifas-Shiman, Wei Perng, Jorge E. Chavarro, Emily Oken
BMC Women's Health.2022;[Epub] CrossRef
Breastfeeding and Sarcopenia in Later Life
Jungun Lee
Korean Journal of Family Medicine.2019; 40(3): 133. CrossRef

6,702 View
121 Download
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4 Crossref

Mammary Paget’s Disease of the Nipple: Relatively Common but Still Unknown to Many: Poh Siang Ooi, Nani Draman, Siti Suhaila Mohd Yusoff, Wan Zainira Wan Zain, Dharmendra Ganasagaran, Hui Heng Chua; Korean J Fam Med 2019;40(4):269-272. Published online November 29, 2018; DOI: https://doi.org/10.4082/kjfm.17.0143

Abstract
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Mammary Paget’s disease is clinically defined as skin inflammation of the nipple area and is an adenocarcinoma of the epidermis of the nipple. The pathogenesis of mammary Paget’s disease is relatively unknown; nonetheless, there are two popular theories that support the underlying carcinoma and de novo carcinogenesis. For the attending medical practitioner, mammary Paget’s disease poses a diagnostic and therapeutic dilemma, especially in the absence of a clinically palpable breast mass. We report a rare case of a 48-year-old Malay woman who presented at Hospital Universiti Sains Malaysia, Kelantan, Malaysia with the symptom of skin erosion on the left nipple and unresponsiveness to multiple topical treatments. A full evaluation and assessment of the patient were conducted, and mammary Paget’s disease was diagnosed.

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Diagnostic imaging challenges of mammary Paget's disease presenting with subtle clinical and imaging features: A case report
Sawitri Darmiati, Andre Elton Heryanto, Primariadewi Rustamadji
Radiology Case Reports.2025; 20(4): 1925. CrossRef
Dermatologic diseases of the breast, areola and nipple
Jenny Deluca, Maria Pichler, Elga Bataraga, Mario Puviani, Klaus Eisendle
JDDG: Journal der Deutschen Dermatologischen Gesellschaft.2025; 23(5): 621. CrossRef
Mammary Paget’s disease in a young woman: A rare occurrence
Chaimae Abourak, Aya Laridi, Ouafaa Chahboune, Siham Oukassem, Asmae Guennouni, Soukaina Bahha, Lina Belkouchi, Nazik Allali, Latifa Chat, Siham El Haddad
Radiology Case Reports.2025; 20(8): 3733. CrossRef
Dermatologische Erkrankungen von Brust, Areola mammae und der Mamille
Jenny Deluca, Maria Pichler, Elga Bataraga, Mario Puviani, Klaus Eisendle
JDDG: Journal der Deutschen Dermatologischen Gesellschaft.2025; 23(5): 621. CrossRef
Paget's disease of the breast: Presentation, treatment, and outcomes in a modern cohort
Dorsa Mousa-Doust, Rebecca Warburton, Jin-Si Pao, Carol Dingee, Amy Bazzarelli, Jieun Newman-Bremang, Elaine McKevitt
The American Journal of Surgery.2024; 231: 18. CrossRef
A revised modified LICAP flap as a novel oncoplastic breast-conserving surgery technique for Mammary Paget’s disease
Timothy Nario, Joseph Do Woong Choi, Sara Wu, Thomas Oh, Jeremy Hsu
Surgery Case Reports.2024; 2: 100020. CrossRef
Mammary Paget's Disease Mimicking Benign and Malignant Dermatological Conditions: Clinical Challenges and Diagnostic Considerations
Renee Scott-Emuakpor, Setareh Reza-Soltani, Sana Altaf, Kaushik NR, Faustyna Kołodziej, Susana Sil-Zavaleta, Monica Nalla, Muhammad Naqib Ullah, Maha R Qureshi, Yasmin Ahmadi, Ali Rezvani, Humza F Siddiqui
Cureus.2024;[Epub] CrossRef
An Overview of Clinical Manifestations of Dermatological Disorders in Intensive Care Units: What Should Intensivists Be Aware of?
Ali Al Bshabshe, Wesam F. Mousa, Nashwa Nor El-Dein
Diagnostics.2023; 13(7): 1290. CrossRef
Mammary Paget’s Disease of Young Females: Case Reports and Comparison With Middle-Aged and Elderly Patients
Chun-yan Lv, Xian-kui Cheng, Zhong-Yue Guo, Li Liu, Jian Cai, Tao Lei, Yan Tang
Clinical Pathology.2023;[Epub] CrossRef
Descripción de un caso de adenomatosis erosiva del pezón: tratamiento quirúrgico
Marcelo Chávez Díaz, Gonzalo Ziegler Rodríguez, Jaime Montes Gil
Revista de Senología y Patología Mamaria.2023; 36(4): 100526. CrossRef
Mammary Paget’s Disease: An Update
Sione Markarian, Dennis R. Holmes
Cancers.2022; 14(10): 2422. CrossRef
An unusual case of longstanding mammary Paget disease presenting with reticulated skin changes
S. K. Dhariwal, E. Rytina, J. C. Sterling
Clinical and Experimental Dermatology.2021; 46(4): 748. CrossRef
Erosive Adenomatosis of the Nipple: A Clinical Diagnostic Challenge

Shuni Ying, Hong Fang, Jianjun Qiao
Clinical, Cosmetic and Investigational Dermatology.2020; Volume 13: 587. CrossRef

6,010 View
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11 Web of Science
13 Crossref

Gastro Oesophageal Reflux Disease Shadowing Anxiety Disorder Causing Prolonged Exposure to Proton Pump Inhibitor: Nur Sharharni Mohd Tahir, Rosnani Zakaria, Nani Draman; Korean J Fam Med 2019;40(5):348-350. Published online November 27, 2018; DOI: https://doi.org/10.4082/kjfm.18.0001

Abstract
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Anxiety disorders are the most prevalent psychiatric disorders in the general population. The relationship between dyspepsia and particularly gastroesophageal reflux disease (GERD) and psychiatric comorbidity such as anxiety is poorly defined. However, GERD was noted to be strongly associated and often coincident in onset with generalized anxiety disorder in the community. In this paper, we report the case of an adult man who presented with severe weight loss and underlying GERD, and was later found to have an anxiety disorder as the cause of both.

6,086 View
114 Download

Association between Breastfeeding and Prevalence of Diabetes in Korean Parous Women: The Korea National Health and Nutrition Examination Survey, 2010–2014: Ha-Nui Kim, Young-Ah Jung, Li-Ly Kang, Hoon-Ki Park, Hwan-Sik Hwang, Kye-Yeung Park; Korean J Fam Med 2018;39(5):273-278. Published online July 9, 2018; DOI: https://doi.org/10.4082/kjfm.17.0023

Abstract
PDF

Background
It is well known that breastfeeding has a significant impact on the health of mothers and children. With the growing importance of breastfeeding, the present study aimed to investigate the relationship between breastfeeding and the prevalence of diabetes in Korean parous women.
Methods
The data of 5,448 premenopausal parous women aged 20–49 years who agreed to participate in the 5th– 6th Korea National Health and Nutrition Examination Survey were analyzed in this study. Control group included women who had not breastfed. The subjects who had breastfed were classified into three groups based on the duration of breastfeeding: 0–6 months, 6–12 months, and >12 months. The variables included age, body mass index, education level, income, alcohol drinking, smoking, family history of diabetes, use of oral contraceptives, the number of pregnancies, and regular exercise.
Results
Among the subjects, the prevalence of diabetes was significantly lower in women who had breastfed compared to those who had not, with an odds ratio of 0.534 (95% confidence interval [CI], 0.289–0.976) in women who breastfed for 0–6 months and 0.575 (95% CI, 0.321–0.990) in women who breastfed for 6–12 months (both P<0.05).
Conclusion
The present study found a reduced prevalence of diabetes in women who had breastfed compared to those who had not. However, no association between the duration of breastfeeding and the prevalence of diabetes could be found.

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Association of Childbirth and Breastfeeding with Diabetes Mellitus in Korean Women
Seulkee Kim, So Yeon Ryu
Journal of Health Informatics and Statistics.2024; 49(2): 109. CrossRef
Knowledge Gaps and Current Evidence Regarding Breastfeeding Issues in Mothers with Chronic Diseases
Rozeta Sokou, Stavroula Parastatidou, Zoi Iliodromiti, Katerina Lampropoulou, Dionysios Vrachnis, Theodora Boutsikou, Aikaterini Konstantinidi, Nicoletta Iacovidou
Nutrients.2023; 15(13): 2822. CrossRef
The relationship between pregnancy count and duration of breast-feeding with metabolic syndrome (Fasa Persian cohort study)
Saeideh Zareei, Fatemeh Behrasi, Mohammad Mehdi Naghizadeh, Fatemeh Talebzadeh, Ali Kharmandar, Mojtaba Farjam, Reza Homayounfar
BMC Women's Health.2023;[Epub] CrossRef
Development and validation of breastfeeding and dietary education package for women with gestational diabetes mellitus
Farhanah Ahmad Shuhaimi, Syahrul Bariah Abdul Hamid, Nurul Ainfarhanah Md Yazid
Journal of Education and Health Promotion.2023;[Epub] CrossRef
Breastfeeding and cardiovascular risk factors
Deepak Bhatnagar, Prachi Bhatnagar
Current Opinion in Lipidology.2019; 30(1): 45. CrossRef
Breastfeeding Can Reduce the Risk of Developing Diabetes
Soo Young Kim
Korean Journal of Family Medicine.2018; 39(5): 271. CrossRef

7,032 View
133 Download
5 Web of Science
6 Crossref

Breast and Cervical Cancer Screening Behavior in Female Cancer Survivors: The Korea National Health and Nutrition Examination Survey, 2007–2012: Eun-Ae Lee, Jinyoung Shin, Eun-Joo Hwang, Jung-Woong Lee; Korean J Fam Med 2017;38(3):116-121. Published online May 23, 2017; DOI: https://doi.org/10.4082/kjfm.2017.38.3.116

Abstract
PDF

Background

The aim of this study was to compare breast and cervical cancer screening rates between female cancer survivors and a population without cancer to identify factors related to cervical and breast cancer screening in cancer survivors.

Methods

We included 17,765 adults (738 cancer survivors and 17,027 individuals without cancer) in this study, all of whom who were 30 years of age or older and participated in the Fourth and Fifth Korean National Health and Nutritional Examination Surveys from 2007–2012. Multiple logistic regression analysis was performed to identify factors related to cervical and breast cancer screening uptake in female cancer survivors.

Results

The screening rate for breast cancer was 56.6%, which was higher than that in the non-cancer control group (P=0.001). The screening rate for cervical cancer was 51.4%, which was not different from that of the non-cancer control group. In terms of breast cancer screening, cancer survivors showed no significant difference in the rate of screening 5 years after their cancer diagnosis. However, cervical cancer survivors were less likely to have cervical cancer screening 10 years after their cancer diagnosis. There was no significant association between cancer screening and sociodemographic factors.

Conclusion

Breast and cervical cancer screening rates in Korean female cancer survivors are low. Secondary primary cancer screening of female cancer survivors needs to be planned in a comprehensive manner, with the consideration of influences beyond sociodemographic factors.

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Temporal Trend in Uptake of the National General Health Checkups and Cancer Screening Program among Korean Women with Breast Cancer
Thi Xuan Mai Tran, Soyeoun Kim, Chihwan Cha, Boyoung Park
Cancer Research and Treatment.2024; 56(2): 522. CrossRef
Screening Adherence for Second Primary Malignancies in Breast Cancer Survivors: Behaviors, Facilitators, and Barriers to Enhance Quality Care
Fernanda Mesa-Chavez, Misael Salazar-Alejo, Cynthia Villarreal-Garza
Seminars in Oncology.2024; 51(5-6): 156. CrossRef
RESEARCH ON THE IMPROVED IMAGE TRACKING ALGORITHM OF ATHLETES’ CERVICAL HEALTH
Jingjing Jiang
Revista Brasileira de Medicina do Esporte.2021; 27(5): 476. CrossRef
Basic Findings Regarding Breast Cancer in Korea in 2015: Data from a Breast Cancer Registry
Sang Yull Kang, Yoo Seok Kim, Zisun Kim, Hyun-Yul Kim, Se Kyung Lee, Kyu-Won Jung, Hyun Jo Youn
Journal of Breast Cancer.2018; 21(1): 1. CrossRef

4,791 View
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4 Crossref

Afatinib-Induced Acute Fatal Pneumonitis in Metastatic Lung Adenocarcinoma: Sang Hoon Yoo, Jin Ah Ryu, Seo Ree Kim, Su Yun Oh, Gu Sung Jung, Dong Jae Lee, Bong Gyu Kwak, Yu Hyun Nam, Kyung Hyun Kim, Young Jun Yang; Korean J Fam Med 2016;37(6):351-355. Published online November 18, 2016; DOI: https://doi.org/10.4082/kjfm.2016.37.6.351

Abstract
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Afatinib is an oral tyrosine kinase inhibitor (TKI) that inhibit Endothelial Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and HER4. The common side effects of EGFR TKI are rash, acne, diarrhea, stomatitis, pruritus, nausea, and loss of appetite. Drug induced pneumonitis is the less common adverse effects of EGFR TKI. Afatinib, 2nd generation EGFR TKI is anticipated to overcome drug resistance from 1st generation EGFR TKI according to preclinical study, and several studies are being conducted to compare clinical efficacy between 1st and 2nd EGFR TKI. Several cases of rug induced acute fatal pneumonitis were reported after use of erlotinib or gefitinib. However, a case of acute fatal pneumonitis associated with afatinib was note reported except drug induced pneumonitis in other clinical study. Here, we present a cases of acute severe pneumonitis related with afatinib in metastatic lung adenocarcinoma with literature review.

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Life‐threatening pneumonitis after first‐line treatment with osimertinib for primary T790M mutated non‐small cell lung cancer
Maik Häntschel, Johannes Niebling, Almut Häring, Max‐Felix Häring, Thorben Groß, Marius Horger, Reimer Riessen, Michael Haap, Richard A Lewis, Michael Böckeler, Jürgen Hetzel
Thoracic Cancer.2020; 11(7): 2044. CrossRef
Afatinib Associated Papulopustular Phototoxic Eruptions- A Novel Case Report
U. Zeenath Begum, M. Krishnakanth, Gayathri Rajesh, Mahalakshmi Veeraraghavan, Sudha R, S. Murugan
Biomedical and Pharmacology Journal.2019; 12(04): 1775. CrossRef
The Relative Risk and Incidence of Immune Checkpoint Inhibitors Related Pneumonitis in Patients With Advanced Cancer: A Meta-Analysis
Ke Ma, Yali Lu, Shanshan Jiang, Jiangong Tang, Xin Li, Yuyang Zhang
Frontiers in Pharmacology.2018;[Epub] CrossRef
Pneumonitis After Precision Oncology Therapies: A Concise Review
Akash Jain, Vickie R. Shannon, Ajay Sheshadri
Journal of Immunotherapy and Precision Oncology.2018; 1(1): 26. CrossRef
Treatment with a programmed cell death-1-specific antibody has little effect on afatinib- and naphthalene-induced acute pneumonitis in mice
Naoki Hamada, Toyoshi Yanagihara, Kunihiro Suzuki, Saiko Ogata-Suetsugu, Eiji Harada, Hironori Mikumo, Masako Arimura-Omori, Yoichi Nakanishi
Biochemical and Biophysical Research Communications.2017; 491(3): 656. CrossRef