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"Frailty"

Clinical Practice Guideline

Clinical Practice Guidelines for Managing Frailty in Community-Dwelling Korean Elderly Adults in Primary Care Settings
Hyo-Sun You, Yu-Jin Kwon, Sunyoung Kim, Yang-Hyun Kim, Ye-seul Kim, Yonghwan Kim, Yong-kyun Roh, Byoungjin Park, Young Kyu Park, Chang-Hae Park, Joung Sik Son, Jinyoung Shin, Hyun-Young Shin, Bumjo Oh, Jae-woo Lee, Jae Yong Shim, Chang Won Won, Ji Won Yoo, Sang-Hyun Lee, Hee-Taik Kang, Duk Chul Lee
Korean J Fam Med 2021;42(6):413-424.   Published online November 20, 2021
DOI: https://doi.org/10.4082/kjfm.21.0162
Aging has become a global problem, and the interest in healthy aging is growing. Healthy aging involves a focus on the maintenance of the function and well-being of elderly adults, rather than a specific disease. Thus, the management of frailty, which is an accumulated decline in function, is important for healthy aging. The adaptation method was used to develop clinical practice guidelines on frailty management that are applicable in primary care settings. The guidelines were developed in three phases: preparation (organization of committees and establishment of the scope of development), literature screening and evaluation (selection of the clinical practice guidelines to be adapted and evaluation of the guidelines using the Korean Appraisal of Guidelines for Research and Evaluation II tool), and confirmation of recommendations (three rounds of Delphi consensus and internal and external reviews). A total of 16 recommendations (five recommendations for diagnosis and assessment, 11 recommendations for intervention of frailty) were made through the guideline development process. These clinical practice guidelines provide overall guidance on the identification, evaluation, intervention, and monitoring of frailty, making them applicable in primary care settings. As aging and “healthy aging” become more and more important, these guidelines are also expected to increase in clinical usefulness.

Citations

Citations to this article as recorded by  
  • Summary of best evidence for prevention and management of frailty
    Yinning Guo, Xueyi Miao, Jieman Hu, Li Chen, Yimeng Chen, Kang Zhao, Ting Xu, Xiaoman Jiang, Hanfei Zhu, Xinyi Xu, Qin Xu
    Age and Ageing.2024;[Epub]     CrossRef
  • Frailty: Assessment and Intervention
    Hana Moon, Geon Ho Lee, DaeHyun Kim
    Keimyung Medical Journal.2024; 43(2): 100.     CrossRef
  • Clinical practice guidelines for frailty vary in quality but guide primary health care: a systematic review
    Huaxin Si, Jiaqi Yu, Qinqin Liu, Yanyan Li, Yaru Jin, Yanhui Bian, Xiaoxia Qiao, Wenyu Wang, Lili Ji, Yan Wang, Jian Du, Cuili Wang
    Journal of Clinical Epidemiology.2023; 161: 28.     CrossRef
  • Yaşlılarda Kırılganlığın Önlenmesi ve Yönetiminde Kanıta Dayalı Yaklaşımlar
    Ayşe Buket DOĞAN, Özlem CANBOLAT
    Sağlık Bilimlerinde Değer.2023; 13(3): 501.     CrossRef
  • Validation of the Korean Academy of Geriatric Dentistry screening questionnaire and oral frailty diagnostic criteria in community-dwelling older adults
    Jeong-Hyun Kang, Seong-Chan Park, Hoi-In Jung, Sun Jae Jung, Hye-Jin Park, Soo-Min Kim, Min-Ji Jo, Yun-Seon Lee, Sun-Young Han
    Epidemiology and Health.2023; 46: e2024008.     CrossRef
  • Up-to-date knowledge of frailty
    Chang Won Won
    Journal of the Korean Medical Association.2022; 65(2): 108.     CrossRef
  • Current status of nutrient intake in Korea: focused on macronutrients
    Seung-Won Oh
    Journal of the Korean Medical Association.2022; 65(12): 801.     CrossRef
  • 7,298 View
  • 182 Download
  • 5 Web of Science
  • 7 Crossref

Review Article

Diagnosis and Management of Frailty in Primary Health Care
Chang Won Won
Korean J Fam Med 2020;41(4):207-213.   Published online July 20, 2020
DOI: https://doi.org/10.4082/kjfm.20.0122
Disability in older adults has become a significant burden, both individually and socially, due to the rapidly aging population in Korea. It is important to manage both frailty and chronic diseases to delay disability. Frailty, which is considered to be a transition phase between healthy status and disability, is defined as a significant decline in functional reserves of multiple organ systems and the resultant extreme vulnerability to stressors, leading to a higher risk of adverse health-related outcomes. The frailty phenotype and frailty index are the most commonly used methods to diagnose frailty. Frailty is related to physical, psychological, cognitive, and social dysfunction, and is sometimes caused by chronic disease. Therefore, primary care providers are ideally situated to incorporate the concept of frailty into their practice, as they are champions in comprehensive care. Although the identification and treatment of frailty is not yet standard practice in primary care, primary care physicians must use the electronic frailty index to identify frailty in all the patients aged ≥65 years in the United Kingdom. In Canada, some insurance companies and governments are using a similar program, which is called the Community Actions and Resources Empowering Seniors model. The clinical practice guidelines of the International Conference of Frailty and Sarcopenia Research, as well as some additional references, will be introduced. Here, we review the current literature on how to diagnose and manage frailty in primary care.

Citations

Citations to this article as recorded by  
  • Comparison of Frailty Rates in Aged Patients Using Updated Clinical Guidelines
    Julia A. Safonova, Daria S. Dyachkova-Gertseva, Ekaterina S. Lapteva
    Russian Family Doctor.2025; 29(2): 77.     CrossRef
  • Frailty and nutrition
    Neil Wilson, William Mullaney
    British Journal of Community Nursing.2024; 29(3): 118.     CrossRef
  • The Chinese translation and cross-cultural adaptation of PRISMA-7 questionnaire: an observational study to establish the accuracy, reliability and validity
    Meredith T. Yeung, Yen Gan, Shu Qi Teo, Kai Quan Lim, Hui Xuan Leow, Myriam Jbabdi, Michel Raiche, Mingxing Yang
    BMC Geriatrics.2024;[Epub]     CrossRef
  • Frailty and Cognitive Function in Middle-Aged and Older Adults With Congenital Heart Disease
    Bo Daelman, Liesbet Van Bulck, Koen Luyckx, Adrienne H. Kovacs, Alexander Van De Bruaene, Magalie Ladouceur, Hsiao-Ling Yang, Ju Ryoung Moon, André Schmidt, Birgitte Lykkeberg, Edward Callus, Michèle de Hosson, Camilla Sandberg, Bengt Johansson, Joanna Hl
    Journal of the American College of Cardiology.2024; 83(12): 1149.     CrossRef
  • Looking out across the front yard: aboriginal peoples’ views of frailty in the community – A qualitative study
    Ebony T. Lewis, Leanne Howard, Uncle Robert Carroll, Adam Howie, Gail Kenning, Adrienne Withall, Kenneth Rockwood, Magnolia Cardona, Kylie Radford, Katherine Schreyenberg, Ruth Peters
    Ethnicity & Health.2024; 29(8): 987.     CrossRef
  • Physical activity and nutrient intake levels according to grip strength among single-household elderly in Korea: data from 2014 and 2019 Korea National Health and Nutrition Examination Survey (KNHANES)
    Mi-Young Park, Nana Chung
    Physical Activity and Nutrition.2024; 28(3): 027.     CrossRef
  • The challenge of home and community older adult care in China: a survey of the capability of primary care physicians in providing geriatric healthcare services
    Xiufang Chen, Kun Xie, Yahui Li, Dan Hu, Yong Chen, Jiaying Chen
    Frontiers in Public Health.2024;[Epub]     CrossRef
  • Patient-reported outcomes in the aging population of adults with congenital heart disease: results from APPROACH-IS
    Philip Moons, Koen Luyckx, Corina Thomet, Werner Budts, Junko Enomoto, Maayke A Sluman, Hsiao-Ling Yang, Jamie L Jackson, Paul Khairy, Stephen C Cook, Shanthi Chidambarathanu, Luis Alday, Erwin Oechslin, Katrine Eriksen, Mikael Dellborg, Malin Berghammer,
    European Journal of Cardiovascular Nursing.2023; 22(4): 339.     CrossRef
  • Nutritional and physical activity issues in frailty syndrome during the COVID-19 pandemic
    Maria Chiara Massari, Viviana Maria Bimonte, Lavinia Falcioni, Antimo Moretti, Carlo Baldari, Giovanni Iolascon, Silvia Migliaccio
    Therapeutic Advances in Musculoskeletal Disease.2023;[Epub]     CrossRef
  • Receiver Operating Characteristic Analysis of Posture and Gait Parameters to Prevent Frailty Condition and Fall Risk in the Elderly
    Valentina Presta, Laura Galuppo, Giancarlo Condello, Francesca Rodà, Prisco Mirandola, Marco Vitale, Mauro Vaccarezza, Giuliana Gobbi
    Applied Sciences.2023; 13(6): 3387.     CrossRef
  • Building resilience and reversing frailty: a randomised controlled trial of a primary care intervention for older adults
    John Travers, Roman Romero-Ortuno, John Langan, Fergal MacNamara, Darren McCormack, Christopher McDermott, Jude McEntire, Joanne McKiernan, Seán Lacey, Peter Doran, Dermot Power, Marie-Therese Cooney
    Age and Ageing.2023;[Epub]     CrossRef
  • Management of Sarcopenia in Primary Care Settings
    Chang Won Won
    Korean Journal of Family Medicine.2023; 44(2): 71.     CrossRef
  • Utilizing multimodal approach to identify candidate pathways and biomarkers and predicting frailty syndrome in individuals from UK Biobank
    Watson Hua-Sheng Tseng, Amrita Chattopadhyay, Nam Nhut Phan, Eric Y. Chuang, Oscar K. Lee
    GeroScience.2023; 46(1): 1211.     CrossRef
  • Biological Age in Congenital Heart Disease—Exploring the Ticking Clock
    Tijs K. Tournoy, Philip Moons, Bo Daelman, Julie De Backer
    Journal of Cardiovascular Development and Disease.2023; 10(12): 492.     CrossRef
  • Unsupervised Home-based Exercise for Rural Frail Elderly: An Evidence-based Case-report
    Gilbert Lazarus, Czeresna Heriawan Soejono
    Activities, Adaptation & Aging.2022; 46(3): 218.     CrossRef
  • Up-to-date knowledge of frailty
    Chang Won Won
    Journal of the Korean Medical Association.2022; 65(2): 108.     CrossRef
  • Born to Age: When Adult Congenital Heart Disease Converges With Geroscience
    Philip Moons, Ariane Marelli
    JACC: Advances.2022; 1(1): 100012.     CrossRef
  • Fragilidade e funcionalidade familiar de idosos da Atenção Domiciliar: estudo transversal analítico
    Gilmara Ramos, Mariane Lurdes Predebon, Fernanda Laís Fengler Dal Pizzol, Naiana Oliveira dos Santos, Lisiane Manganelli Girardi Paskulin, Ana Karina Silva da Rocha Tanaka, Idiane Rosset
    Acta Paulista de Enfermagem.2022;[Epub]     CrossRef
  • Predictive Ability of the Three-Time Stand and Walk Test to Determine Frailty and its Associations with Fear of Falling and Cognitive Function in Community-Dwelling Older Adults
    Sirintip Kumfu, Puttipong Poncumhak
    Annals of Geriatric Medicine and Research.2022; 26(4): 316.     CrossRef
  • Current status of nutrient intake in Korea: focused on macronutrients
    Seung-Won Oh
    Journal of the Korean Medical Association.2022; 65(12): 801.     CrossRef
  • World Health Organization Integrated Care for Older People (ICOPE) and the Integrated Care of Older Patients with Frailty in Primary Care (ICOOP_Frail) Study in Korea
    Chang Won Won, Eunmi Ha, Eunjin Jeong, Miji Kim, Juhyun Park, Ja Euk Baek, Sungouk Kim, Sung Bae Kim, Jihun Roh, Jee Hye Choi, Seung Youn Jeon, Heeeun Jung, Daehyun Lee, Yuri Seo, Hyungeun Shin, Heesun Kim
    Annals of Geriatric Medicine and Research.2021; 25(1): 10.     CrossRef
  • Clinical Practice Guidelines for Managing Frailty in Community-Dwelling Korean Elderly Adults in Primary Care Settings
    Hyo-Sun You, Yu-Jin Kwon, Sunyoung Kim, Yang-Hyun Kim, Ye-seul Kim, Yonghwan Kim, Yong-kyun Roh, Byoungjin Park, Young Kyu Park, Chang-Hae Park, Joung Sik Son, Jinyoung Shin, Hyun-Young Shin, Bumjo Oh, Jae-woo Lee, Jae Yong Shim, Chang Won Won, Ji Won Yoo
    Korean Journal of Family Medicine.2021; 42(6): 413.     CrossRef
  • Implications of frailty interventions from Korean frailty and aging cohort study
    Chang Won Won
    AGING MEDICINE.2021; 4(4): 247.     CrossRef
  • Perceived Recovery Time from Common Cold as a Possible Indicator of Physical Resilience
    Yoonki Kim, Chang Won Won, Sunyoung Kim, ByungSung Kim, Miji Kim, Eunjin Jeong, Jisoo Yang, Hyona Lee
    Annals of Geriatric Medicine and Research.2021; 25(3): 204.     CrossRef
  • Grip Strength as a Cardiometabolic Marker
    Jungun Lee
    Korean Journal of Family Medicine.2020; 41(5): 271.     CrossRef
  • 9,784 View
  • 170 Download
  • 23 Web of Science
  • 25 Crossref

Original Article

Correlation between Frailty Level and Adverse Health-related Outcomes of Community-Dwelling Elderly, One Year Retrospective Study
Eun Young Shim, Seung Hyun Ma, Sun Hyoung Hong, Yun Sang Lee, Woo Youl Paik, Deok Seoung Seo, Eun Young Yoo, Mee Young Kim, Jong Lull Yoon
Korean J Fam Med 2011;32(4):249-256.   Published online May 31, 2011
DOI: https://doi.org/10.4082/kjfm.2011.32.4.249
Background

Frailty is considered to be a clinical syndrome characterized by decreased physiological reserves associated with a greater risk of health-related problems, hospitalization, and death. The current study examined hospitalization, falls, cognitive decline and disability between robust, prefrail and frail elderly in one year.

Methods

110 participants aged 65 or more who visited two senior welfare centers in Seoul from February 2008 to June 2008 were surveyed again from March 2009 to June 2009 with demographic characteristics, number of chronic diseases and medication, study of osteoporotic fractures (SOF) frailty index, instrumental activity of daily living (IADL), depression, mini-mental state examination-Korean version (MMSE-K), falling history and admission history within one year. These results were compared with participants' previous survey done one year ago.

Results

Among total 110 subjects, 48 (44%) robust, 30 (27%) prefrail, and 32 (29%) frail subjects changed to 26 (24%), 54 (49%), and 30 (27%) respectively over the year. There were statistical significances in age, number of chronic disease, depressive mood, MMSE, falls, hospitalization, IADL disability contributing to frailty (P < 0.05). Frailty defined by SOF frailty index was associated with greater risk of adverse outcomes. Frail subjects had a higher age-adjusted risk of cognitive function decline (odds ratio [OR], 3.57), disability (OR, 9.64), fall (OR, 5.42), and hospitalization (OR, 4.45; P < 0.005).

Conclusion

The frailty index like SOF frailty index might predict risk of falls, disability, hospitalization, and cognitive decline in the elderly, emphasizing special attention to the individuals showing frailty in outpatient examination.

Citations

Citations to this article as recorded by  
  • Sex differences in the association between sleep duration and frailty in older adults: evidence from the KNHANES study
    Beomman Ha, Mijin Han, Wi-Young So, Seonho Kim
    BMC Geriatrics.2024;[Epub]     CrossRef
  • Relationship between frailty and mortality after gastrectomy in older patients with gastric cancer
    Ju-Ri Jeong, Ji-Won Choi, Seong-Yeob Ryu, Yu-Ri Choe
    Journal of Geriatric Oncology.2022; 13(1): 67.     CrossRef
  • Prevalence of frailty and mobility disability in older people living in retirement villages
    Janet Cobden, Marcos de Noronha, Michael Kingsley
    Australasian Journal on Ageing.2022; 41(2): 222.     CrossRef
  • Cross-sectional associations of physical frailty with fall, multiple falls and fall-injury among older Indian adults: Findings from LASI, 2018
    Shriya Thakkar, Muhammad T., Shobhit Srivastava, David G. Greenhalgh
    PLOS ONE.2022; 17(8): e0272669.     CrossRef
  • Physical Frailty and Fall Risk in Community-Dwelling Older Adults: A Cross-Sectional Study
    Jiraporn Chittrakul, Penprapa Siviroj, Somporn Sungkarat, Ratana Sapbamrer
    Journal of Aging Research.2020; 2020: 1.     CrossRef
  • Fear of Falling and Mortality among Older Adults in Korea: Analysis of the Korean Longitudinal Study of Aging
    Ari Lee, Jungun Lee, Gyumin Lee, Dong Ryul Lee
    Korean Journal of Family Medicine.2020; 41(4): 243.     CrossRef
  • Diagnosis and Management of Frailty in Primary Health Care
    Chang Won Won
    Korean Journal of Family Medicine.2020; 41(4): 207.     CrossRef
  • Prevalence and Factors Associated with Frailty and Cognitive Frailty Among Community-Dwelling Elderly with Knee Osteoarthritis
    Kulthanit Wanaratna, Weerasak Muangpaisan, Vilai Kuptniratsaikul, Chalobol Chalermsri, Apiwan Nuttamonwarakul
    Journal of Community Health.2019; 44(3): 587.     CrossRef
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    R. Vella Azzopardi, I. Beyer, S. Vermeiren, M. Petrovic, N. Van Den Noortgate, I. Bautmans, E. Gorus
    Ageing Research Reviews.2018; 43: 10.     CrossRef
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    Mei‐Hsun Cheng, Shu‐Fang Chang
    Journal of Nursing Scholarship.2017; 49(5): 529.     CrossRef
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    Crislainy Vieira Freitas, Edilene do Socorro Nascimento Falcão Sarges, Karlo Edson Carneiro Santana Moreira, Saul Rassy Carneiro
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    Ji-Young Kang, Cheol-Hwan Kim, Eun-Ju Sung, Ho-Cheol Shin, Woon-Jung Shin, Keun-Hyeong Jung
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    John E. Morley
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Review

Integrative Approach to Elderly Frailty.
Byoung Jin Park, Yong Jae Lee
Korean J Fam Med 2010;31(10):747-754.   Published online October 20, 2010
DOI: https://doi.org/10.4082/kjfm.2010.31.10.747
Elderly frailty has been recognized as a distinct clinical syndrome with a physiologic basis. It reflects a decreased functional reserve and consequent reduction in resilience to any stressors. It is important to understand that frailty process could be a transitional state with dynamic properties: normal aging→pre-frail→frailty→complication status. Hence, frailty could be preventable and its progression may be delayed. Furthermore, there is the potential reversibility of many of its features. The earlier stages of frailty might not be clinically apparent, but later stages manifest as significant deficits accumulate. The major phenotype of frailty includes weight loss, sarcopenia, relative inactivity, decreased balance and mobility, decreased cognitive function, and impaired nutritional status. Therefore, frail patients could be implicated by decreased performance status and have a significantly increased risk of cardiovascular diseases, cancer, falls and mortality. Regular exercise, essential amino acid and vitamin D are recommendable to prevent and treat elderly frailty, but hormone replacement therapy does not have consistent evidence yet. In upcoming (super) aging society, the importance of elderly frailty would be more noticed and multidisplinary approach should be actively performed.

Citations

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  • Healthy aging of frail older adults in the community: A hybrid concept analysis
    Ji Su Seo, A-Hyun Ryu, Rhayun Song
    Journal of Korean Gerontological Nursing.2023; 25(3): 284.     CrossRef
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    Jeong Sook Park, Yun Jung Oh
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    Eunok Park, Mi Yu
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    Chang Won Won M.D.
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    Román Romero Ortuño
    Revista Española de Geriatría y Gerontología.2011; 46(5): 243.     CrossRef
  • 3,044 View
  • 91 Download
  • 14 Crossref
Original Article
Correlation between Frailty Level and Disability of the Elderly and Frailty Related Factors.
Seung Hyun Ma, Ki Yun Jeung, Sun Hyoung Hong, Eun Young Shim, Sang Ho Yoo, Mee Young Kim, Jong Lull Yoon
Korean J Fam Med 2009;30(8):588-597.   Published online August 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.8.588
Background
Frailty is a wasting syndrome that presents loss of physiological function by aging, lowering of reserve capacity, and disability of body system. It is currently being considered an important issue in geriatrics. This study examined frailty level of Korean elderly in community and whether frailty can be meaningful a predictive factor for functional disability. Methods: Demographic characteristics, the number of chronic diseases and medications, cardiovascular health study (CHS) frailty index, study of osteoporotic fractures (SOF) frailty index, activities of daily living, Instrumental activities of daily living, depression, mini-mental state examination (MMSE) and fall history were examined for 302 men and women over 65 years old who visited the three community seniors welfare centers from February 2008 to June 2008. Results: There were defi nite differences of frailty status by age, educational level, marital status, monthly income, body mass index, the number of chronic diseases, the number of medications, depression, MMSE and fall history (P < 0.05), except in gender (P < 0.432). In logistic regression analysis for functional disability with frailty status defi ned by SOF frailty index, odds ratio to dependency of instrumental activities of daily living (IADL) from the healthy to the prefrail stage increased 6.84 times while from the healthy to the frail stage increased 130.87 times. These effects still increased after covariate adjustment. Also, the CHS frailty index showed the same result although there was some difference in odds ratio.Conclusion: There were meaningful correlations of frailty with functional disability when dividing Korean elderly's frailty levels into the healthy, the prefrail and the frail stages.

Citations

Citations to this article as recorded by  
  • Association between health, dietary, and oral health factors and frailty
    Soo-Hwa Kim, Su-Jin Han
    Journal of Korean Society of Dental Hygiene.2025; 25(1): 49.     CrossRef
  • Relationship between frailty and mortality after gastrectomy in older patients with gastric cancer
    Ju-Ri Jeong, Ji-Won Choi, Seong-Yeob Ryu, Yu-Ri Choe
    Journal of Geriatric Oncology.2022; 13(1): 67.     CrossRef
  • The Factors Affecting Frailty among the Elderly in Korea: A Study Using the Frailty Cohort
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