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Review Article

Gender-Based Violence and Women Reproductive Health in War Affected Area
Manar Shalak, Favor Markson, Manoj Nepal
Korean J Fam Med 2024;45(1):12-17.   Published online November 27, 2023
DOI: https://doi.org/10.4082/kjfm.23.0169
Correction in: Korean J Fam Med 2024;45(5):302
Manifestations of gender-based violence although many, and sometimes more pronounced in areas of armed conflict, go unnoticed due to multiple factors. Gender-based violence targeted towards women, affect their overall health negatively, particularly the reproductive well-being. Major conflicts arising in the Middle East over the past 10–15 years, ranging from the Arab uprising to the Syrian civil war, have drawn attention world-wide. This study aims to shed light on the importance of recognizing violence against women, its effect on their reproductive health, and the policies that should be implemented to limit its adverse impact. Towards this end, we have highlighted the important role played by all healthcare professionals, epidemiologists, and surveyors working in peace and war areas to recognize such atrocities towards women.

Citations

Citations to this article as recorded by  
  • Reflecting on progress and challenges: the Korean Journal of Family Medicine in 2024
    Seung-Won Oh
    Korean Journal of Family Medicine.2025; 46(2): 55.     CrossRef
  • Resettlement and Relational Adjustment: Gender and Liberian Couple Relationships After Forced Migration
    Lekie Dwanyen, Sarah Griffes, Elizabeth Wieling
    Journal of Marriage and Family.2025;[Epub]     CrossRef
  • War impact on mental health and well-being among Ukrainian and Israeli women: A cross-national comparison
    Alexander Reznik, Valentyna Pavlenko, Anton Kurapov, Liudmyla Zavatska, Nataliia Korchakova, Iuliia Pavlova, Shai-li Romem-Porat, Richard Isralowitz
    Cambridge Prisms: Global Mental Health.2025;[Epub]     CrossRef
  • Women’s Health and Primary Care
    Seung-Won Oh
    Korean Journal of Family Medicine.2024; 45(1): 1.     CrossRef
  • Correction: Gender-Based Violence and Women Reproductive Health in War Affected Area
    Manar Shalak, Favour Ekerete Markson, Manoj Nepal
    Korean Journal of Family Medicine.2024; 45(5): 302.     CrossRef
  • 5,099 View
  • 105 Download
  • 6 Web of Science
  • 5 Crossref

Original Articles

Decision-Making on Contraceptive Use among Women Living with Human Immunodeficiency Virus in Malaysia: A Qualitative Inquiry
Surianti Sukeri, Zaharah Sulaiman, Noor Aman Hamid, Siti Aishah Ibrahim
Korean J Fam Med 2024;45(1):27-36.   Published online October 18, 2023
DOI: https://doi.org/10.4082/kjfm.23.0088
Background
Malaysia is the first country in the Western Pacific Region to receive the validation certificate for the elimination of mother-to-child transmission of human immunodeficiency virus (HIV). The validation report recommends making sexual and reproductive health and rights of women living with HIV a priority. This article explores and assesses the sexual and reproductive health, rights, and access to healthcare services of Malaysia’s women living with HIV (WLHIV).
Methods
A qualitative secondary analysis conducted on 73 WLHIV from all over Malaysia comprised 11 in-depth interviews and 16 focus group discussions. Data were extracted from the original interview transcripts that emerged from the following questions: (1) “What are your experiences as a woman living with HIV in relation to your sexual and reproductive health and rights?” (2) “What are your experiences in accessing contraception?” (3) “What are your day-to-day experiences as a woman living with HIV?” Data were analyzed using thematic analysis.
Results
Four themes emerged from the study findings: “lack of negotiation,” “idealism in pregnancy,” “coping with restrictions,” and “past and future fears.” The four themes are grounded in religion, a patriarchal culture, meaning and expectations of motherhood, taking risks and going against medical advice to pursue fertility desires, fear of HIV transmission, and the side effects of contraceptive use.
Conclusion
The complexities involved in decision-making regarding contraceptive use revealed how WLHIV may have unresolved reproductive health needs inconsistent with healthcare providers’ focus on HIV management and prevention. Suggestions are made for improving the sexual and reproductive health and rights of WLHIV in Malaysia, which include establishing a reproductive health counseling program.

Citations

Citations to this article as recorded by  
  • Reflecting on progress and challenges: the Korean Journal of Family Medicine in 2024
    Seung-Won Oh
    Korean Journal of Family Medicine.2025; 46(2): 55.     CrossRef
  • Women’s Health and Primary Care
    Seung-Won Oh
    Korean Journal of Family Medicine.2024; 45(1): 1.     CrossRef
  • Postpartum modern family planning among women living with HIV attending care at health facilities in Busia County, Kenya
    Florence Zawedde Tebagalika, Derrick Kimuli, Dennis Walusimbi, Edna Nyang’echi, Louisa Ndunyu
    Contraception and Reproductive Medicine.2024;[Epub]     CrossRef
  • 4,926 View
  • 104 Download
  • 3 Web of Science
  • 3 Crossref
Relationship between Serum Testosterone Level and Carotid Intima-Media Thickness among Korean Men and Postmenopausal Women
Miso Kim, Yohwan Yeo, Yun-Mi Song
Korean J Fam Med 2022;43(6):374-380.   Published online November 20, 2022
DOI: https://doi.org/10.4082/kjfm.21.0204
Background
Given that the role of serum testosterone on incident cardiovascular disease has been uncertain, it is necessary to find out the relationship between serum testosterone and carotid atherosclerosis.
Methods
The study participants included 1,302 Korean adults (873 men and 429 postmenopausal women) who participated in the Healthy Twin Study and were not receiving androgen deprivation therapy. The participants were classified into three groups: men aged <40 and ≥40 years and postmenopausal women. Total testosterone (TT) and sex hormone-binding globulin (SHBG) concentrations were measured using electrochemiluminescence immunoassays, and free testosterone (cFT) levels were calculated using Vermeulen’s method. Carotid intima-media thickness (IMT) was measured at three levels using a high-resolution B-mode ultrasound equipped with a 7-MHz linear transducer. The associations between sex hormone concentrations and carotid IMT were evaluated using a mixed linear regression analysis.
Results
After adjusting for cardiovascular risk factors, TT was found to be inversely associated with common carotid IMT in men aged ≥40 years, with a 4.5% decrease in common carotid IMT for every one-standard deviation increase in TT concentration (P=0.0063). In contrast, TT was not significantly associated with carotid IMT in all segments in men aged <40 years and postmenopausal women. Additionally, SHBG and cFT were not associated with carotid IMT in any segment.
Conclusion
The significant association between TT level and common carotid IMT in men aged ≥40 years suggests that decreased testosterone levels are involved in the development of atherosclerosis in men.

Citations

Citations to this article as recorded by  
  • Serum norethisterone (NET) levels in NET-enanthate (NET-EN) injectable contraception users substantially interfere with testosterone immunoassay measurements and confound interpretation of biological outcomes
    Chanel Avenant, Johnson Mosoko Moliki, Alexis J. Bick, Sigcinile Dlamini, Mandisa Singata-Madliki, G. Justus Hofmeyr, Pai-Lien Chen, Karl-Heinz Storbeck, Donita J. Africander, David W. Erikson, Janet P. Hapgood
    Contraception and Reproductive Medicine.2025;[Epub]     CrossRef
  • Refined metabolite profiling in the collateral circulation of chronic total occlusion of coronary arteries: Insights from a metabolomics investigation
    Hu Sigan, Li Min, Cheng Zengwei, Gao Shiyi, Kang Pinfang, Gao Dasheng
    Atherosclerosis Plus.2024; 55: 63.     CrossRef
  • 4,448 View
  • 60 Download
  • 2 Web of Science
  • 2 Crossref
The Association of Body Fat and Arterial Stiffness Using the Brachial-Ankle Pulse Wave Velocity
Gyu Lee Kim, Hye Rim Hwang, Yun Jin Kim, Sang Yeoup Lee, Jeong Gyu Lee, Dong Wook Jeong, Yu Hyeon Yi, Young Jin Tak, Seung Hun Lee, A Rum Park
Korean J Fam Med 2018;39(6):347-354.   Published online October 31, 2018
DOI: https://doi.org/10.4082/kjfm.17.0045
Background
BMI alone may not serve as an index of obesity because it does not reflect body composition. The present study aimed to compare arterial stiffness as assessed by the brachial-ankle pulse wave velocity (ba-PWV) among groups defined by body fat percentage (pBF) and BMI.
Methods
This cross-sectional study was based on 1,700 participants (1,044 men and 656 women) who completed a health screening examination at a national hospital between January 2011 and February 2016. Participants were divided into four groups according to BMI and pBF: normal fat and normal weight (NFNW); excessive fat and normal weight (EFNW); normal fat and obese (NFO); and excessive fat and obese (EFO). The ba-PWV and other cardiometabolic factors were compared among the four groups in men and women separately.
Results
For both sexes, the NFNW group had a lower metabolic risk compared to that in the other groups (EFNW, NFO, and EFO). After adjusting for multiple variables, the NFO males had a significantly lower ba-PWV compared to those in the other groups, including NFNW males. The NFO group had significantly more skeletal muscle mass and muscle mass compared the other groups (P<0.05). Among women, the NFNW group had a significantly lower ba-PWV compared the other groups, even after adjusting for multiple variables.
Conclusion
Lower pBF in obese men may be associated with improved cardiovascular risk.

Citations

Citations to this article as recorded by  
  • Improved fatty acid profile reduces body fat and arterial stiffness in obese adolescents upon combinatorial intervention with exercise and dietary restriction
    Lei Xu, Xiaoyu Zou, Zhiqiang Gao, Caifeng Mao, Hang Su, Chunyan Li, Ning Chen
    Journal of Exercise Science & Fitness.2021; 19(4): 234.     CrossRef
  • Borderline-High Mean Corpuscular Volume Levels Are Associated with Arterial Stiffness among the Apparently Healthy Korean Individuals
    Haneul Kwon, Byoungjin Park
    Korean Journal of Family Medicine.2020; 41(6): 387.     CrossRef
  • 7,459 View
  • 104 Download
  • 2 Web of Science
  • 2 Crossref
Prevalence and Predictive Factors of Sexual Dysfunction in Iranian Women: Univariate and Multivariate Logistic Regression Analyses
Ashraf Direkvand-Moghadam, Zainab Suhrabi, Malihe Akbari, Azadeh Direkvand-Moghadam
Korean J Fam Med 2016;37(5):293-298.   Published online September 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.5.293
Background

Female sexual dysfunction, which can occur during any stage of a normal sexual activity, is a serious condition for individuals and couples. The present study aimed to determine the prevalence and predictive factors of female sexual dysfunction in women referred to health centers in Ilam, the Western Iran, in 2014.

Methods

In the present cross-sectional study, 444 women who attended health centers in Ilam were enrolled from May to September 2014. Participants were selected according to the simple random sampling method. Univariate and multivariate logistic regression analyses were used to predict the risk factors of female sexual dysfunction. Diffe rences with an alpha error of 0.05 were regarded as statistically significant.

Results

Overall, 75.9% of the study population exhibited sexual dysfunction. Univariate logistic regression analysis demonstrated that there was a significant association between female sexual dysfunction and age, menarche age, gravidity, parity, and education (P<0.05). Multivariate logistic regression analysis indicated that, menarche age (odds ratio, 1.26), education level (odds ratio, 1.71), and gravida (odds ratio, 1.59) were independent predictive variables for female sexual dysfunction.

Conclusion

The majority of Iranian women suffer from sexual dysfunction. A lack of awareness of Iranian women's sexual pleasure and formal training on sexual function and its influencing factors, such as menarche age, gravida, and level of education, may lead to a high prevalence of female sexual dysfunction.

Citations

Citations to this article as recorded by  
  • Translation and investigation of the psychometric properties of the revised female sexual distress scale among Iranian couples
    Roghieh Bayrami, Hamid Sharif-Nia, Roksana Janghorban, Daniz Montakhabi Oskuii, Esmaeil Hoseinzadeh
    Scientific Reports.2025;[Epub]     CrossRef
  • Machine learning driven biomarker selection for medical diagnosis
    Divyagna Bavikadi, Ayushi Agarwal, Shashank Ganta, Yunro Chung, Lusheng Song, Ji Qiu, Paulo Shakarian, John Adeoye
    PLOS One.2025; 20(6): e0322620.     CrossRef
  • Função sexual durante o período gestacional: um estudo transversal
    Jamile Monteiro De Andrade, Elisa Helena Borges Filgueira, Amannda Gabrielle da Cruz Silva, Bárbara Gabrielle Morais Maciel, Hayandra Ferreira Dias Mota, Mariana Cecchi Salata
    Health Residencies Journal.2025;[Epub]     CrossRef
  • Predicting 28-day all-cause unplanned hospital re-admission of patients with alcohol use disorders: a machine learning approach
    Jingxiang Zhang, Siyu Qian, Guoxin Su, Chao Deng, David Reid, Barbara Sinclair, Ping Yu
    Alcohol and Alcoholism.2025;[Epub]     CrossRef
  • Sexual dysfunction, marital relationship, and subjective quality of life among women with schizophrenia: Analytical case-control study
    Puja Kumari, Rajesh Kumar, Jitendra Rohilla
    Indian Journal of Psychiatry.2024; 66(3): 280.     CrossRef
  • The effect of rose damascene extract on anxiety and sexual function of breastfeeding women: a randomized controlled trial
    Gohar Akbarzadeh, Parvin Abedi, Shayesteh Jahanfar, Hossein Sadeghi Mansurkhani, Ahmad Fakhri, Elham Maraghi
    Frontiers in Medicine.2024;[Epub]     CrossRef
  • Sexual myths during pregnancy: a comparative study
    Hüsniye Dinç Kaya, Tülay Yılmaz, Sevil Günaydın, Emine Nur Çalımlı, Elham Sadeghi
    Journal of Obstetrics and Gynaecology.2022; 42(4): 587.     CrossRef
  • Impact of pelvic floor muscle strength on female sexual function: retrospective multicentric cross-sectional study
    Luísa Pasqualotto, Cássio Riccetto, Ana Flávia Biella, Joseane Marques, Larissa Carvalho Pereira, Fabíola Kênia Alves, Anna Lygia Barbosa Lunardi, Délcia Barbosa de Vasconcelos Adami, Anita Nagib, Natalia Martinho, Adriana Piccini, Tirza Sathler, Valeria
    International Urogynecology Journal.2022; 33(6): 1591.     CrossRef
  • The Effect of the PLISSIT Model on Sexual Functions: A Systematic Review
    Serap KIRICI, Emel EGE
    Bandırma Onyedi Eylül Üniversitesi Sağlık Bilimleri ve Araştırmaları Dergisi.2021; 3(3): 199.     CrossRef
  • Sexual functions in pregnancy: different situations in near geography:a case study on Turkey, Iran and Greece
    Mahide Demireloz Akyuz, Esin Ceber Turfan, Serap Cetintas Oner, Tugce Sakar, Dilek Mamik Aktay
    The Journal of Maternal-Fetal & Neonatal Medicine.2020; 33(2): 222.     CrossRef
  • Effects ofWithania somniferaon Reproductive System: A Systematic Review of the Available Evidence
    Ramin Nasimi Doost Azgomi, Afshar Zomorrodi, Hossein Nazemyieh, Seyed Mohammad Bagher Fazljou, Homayoun Sadeghi Bazargani, Fatemeh Nejatbakhsh, Arezoo Moini Jazani, Yadollah Ahmadi AsrBadr
    BioMed Research International.2018; 2018: 1.     CrossRef
  • 5,617 View
  • 38 Download
  • 10 Web of Science
  • 11 Crossref

Brief Communication

Prevalence and Risk Factors of Domestic Violence against Iranian Women: A Cross-Sectional Study
Fathola Mohamadian, Ataollah Hashemian, Maryam Bagheri, Ashraf Direkvand-Moghadam
Korean J Fam Med 2016;37(4):253-258.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.253
Background

Violence against women in families is the most common form of violence against them. The purpose of this study was to determine the prevalence of domestic violence and its effects on married women of Ilam.

Methods

In this descriptive-sectional research, 334 married women referred to medical health centers in Ilam were selected to participate using a random sampling method. After obtaining their consent to participate in the study, participants responded to a 46 items questionnaire and responses were analyzed using IBM SPSS for Windows ver. 20.0 (IBM Co., Armonk, NY, USA).

Results

The majority of the participants reported experiencing domestic violence and emotional violence was more prevalent than other kinds of violence. Logistic regression analysis showed that lower education level, marriage at a younger age, shorter duration of marriage, fewer children, being a housewife, and husband's unemployment had a significant relationship with domestic violence against women.

Conclusion

The high prevalence of wife abuse in Ilam especially emotional violence due to lower education levels and marriage at younger age could be a serious threat for women's health as well as for other members of the family. This could be a grounding factor for other social harms such as suicide and this issue must be studied from legal, religious, and cultural standpoints.

Citations

Citations to this article as recorded by  
  • Determining domestic violence against women using machine learning methods: The case of Türkiye
    Fatma Başaran, Pınar Duru
    Journal of Evaluation in Clinical Practice.2025;[Epub]     CrossRef
  • Factors affecting domestic violence against women in Iran: a scoping review
    Leila Manzouri, Maryam Seyed-Nezhad, Ghasem Rajabi-Vasokolaei, Alireza Arabi, Mohammad Moardi-Joo
    BMC Women's Health.2025;[Epub]     CrossRef
  • Aftermath of COVID-19: Exploring the Perception of Violence Against Women in the Middle East and North Africa
    Mansour Pourmehdi
    Journal of Interpersonal Violence.2024; 39(9-10): 2076.     CrossRef
  • Prevalence and factors associated with anxiety disorder among married women exposed to violence in rural area, Ismailia, Egypt: A cross-sectional study
    Almaza A. Salim, Mona Elsayed, Mohamed Hafez Mohamed, Heba Yousef, Mohamed S. Hemeda, Alaa Ramadan, Nathan Ezie Kengo, Noha M. Abu Bakr Elsaid
    Global Epidemiology.2024; 7: 100139.     CrossRef
  • Domestic Violence Against Women in North African and Middle Eastern Countries: A Scoping Review
    Sezer Kisa, Rusan Gungor, Adnan Kisa
    Trauma, Violence, & Abuse.2023; 24(2): 549.     CrossRef
  • Investigating the Extent and Social-Demographic Determinants of Domestic Violence Against Women
    Roghayeh Khosravi, Serajeddin Mahmoudiani, Manzar Abedi
    Shiraz E-Medical Journal.2023;[Epub]     CrossRef
  • Domestic violence against married women during the COVID-19 pandemic in Egypt
    Mira M. Abu-Elenin, Ahmed A. Elshora, Mohamed Saad Sadaka, Doaa E. Abdeldaim
    BMC Women's Health.2022;[Epub]     CrossRef
  • Domestic violence against women during coronavirus (COVID-19) pandemic lockdown in Egypt: a cross-sectional study
    Noha M. Abu Bakr Elsaid, Shaimaa A. Shehata, Haydy Hassan Sayed, Heba Saber Mohammed, Zeinab F. Abdel-Fatah
    Journal of the Egyptian Public Health Association.2022;[Epub]     CrossRef
  • Structured Spatial Modeling and Mapping of Domestic Violence Against Women of Reproductive Age in Rwanda
    Faustin Habyarimana, Temesgen Zewotir, Shaun Ramroop
    Journal of Interpersonal Violence.2021; 36(5-6): 2430.     CrossRef
  • Investigating the Frequency of Physical Violence Against Women by Their Husbands in Women Referring to Health Centers of Hamadan in 2017
    Elham Khanlarzadeh, Nasrin Jiryaee
    Violence and Gender.2021; 8(1): 28.     CrossRef
  • A Qualitative Study of the Health-Related Perceptions of Married Iranian Women Who Have Experienced Domestic Violence
    Nasrin Rezaee, Marjan Mardani-Hamooleh
    Journal of Forensic Nursing.2021; 17(1): 34.     CrossRef
  • Spatial distribution and predictors of domestic violence against women: evidence from analysis of Ethiopian demographic health survey 2016
    Elias Seid, Tesfahun Melese, Kassahun Alemu
    BMC Women's Health.2021;[Epub]     CrossRef
  • Intimate partner abuse among couples during pregnancy and its predictors as reported by pregnant women visiting governmental health care centres in Tabriz, Iran
    Ellahe Bahrami-Vazir, Sakineh Mohammad-Alizadeh-Charandabi, Fatemeh Ghelichkhani, Azam Mohammadi, Mojgan Mirghafourvand
    Journal of Biosocial Science.2020; 52(3): 400.     CrossRef
  • Domestic violence among married women of reproductive age in Zimbabwe: a cross sectional study
    Joseph Lasong, Yuan Zhang, Kahindo P. Muyayalo, Olivia Adhiambo Njiri, Simon Afewerki Gebremedhin, Chrissie S. Abaidoo, Chun Yan Liu, Huiping Zhang, Kai Zhao
    BMC Public Health.2020;[Epub]     CrossRef
  • The prevalence of domestic violence and its association with family factors: a cross-sectional study among pregnant women in urban communities of Hengyang City, China
    Baohua Zheng, Xidi Zhu, Zhao Hu, Wensu Zhou, Yunhan Yu, Shilin Yin, Huilan Xu
    BMC Public Health.2020;[Epub]     CrossRef
  • Domestic violence and suicide attempts among married women: A case–control study
    Farzad Rahmani, Shiva Salmasi, Farnaz Rahmani, Jamie Bird, Elnaz Asghari, Navide Robai, Mohammad Asghari Jafarabadi, Leila Gholizadeh
    Journal of Clinical Nursing.2019; 28(17-18): 3252.     CrossRef
  • The Effect of Resilience and Stress Coping Styles on Suicide Attempts in Females Reporting Spouse-Related Abuse
    Sepideh Hajian, Simin Kasaeinia, Mahboubeh Ahmadi Doulabi
    Iranian Journal of Psychiatry and Behavioral Sciences.2018;[Epub]     CrossRef
  • Factors Associated With Domestic Violence Against Women in Iran: An Exploratory Multicenter Community-Based Study
    Mohsen Saffari, Syed Asadullah Arslan, Mir Saeid Yekaninejad, Amir H. Pakpour, Faten Al Zaben, Harold G. Koenig
    Journal of Interpersonal Violence.2017;[Epub]     CrossRef
  • 7,062 View
  • 68 Download
  • 17 Web of Science
  • 18 Crossref
Original Articles
Sex Difference in the Association between Serum Homocysteine Level and Non-Alcoholic Fatty Liver Disease
Bo-Youn Won, Kyung-Chae Park, Soo-Hyun Lee, Sung-Hwan Yun, Moon-Jong Kim, Kye-Seon Park, Young-Sang Kim, Ji-Hee Haam, Hyung-Yuk Kim, Hye-Jung Kim, Ki-Hyun Park
Korean J Fam Med 2016;37(4):242-247.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.242
Background

The relationship between serum homocysteine levels and non-alcoholic fatty liver disease is poorly understood. This study aims to investigate the sex-specific relationship between serum homocysteine level and non-alcoholic fatty liver disease in the Korean population.

Methods

This cross-sectional study included 150 men and 132 women who participated in medical examination programs in Korea from January 2014 to December 2014. Patients were screened for fatty liver by abdominal ultrasound and patient blood samples were collected to measure homocysteine levels. Patients that consumed more than 20 grams of alcohol per day were excluded from this study.

Results

The homocysteine level (11.56 vs. 8.05 nmol/L) and the proportion of non-alcoholic fatty liver disease (60.7% vs. 19.7%) were significantly higher in men than in women. In men, elevated serum homocysteine levels were associated with a greater prevalence of non-alcoholic fatty liver disease (quartile 1, 43.6%; quartile 4, 80.6%; P=0.01); however, in females, there was no significant association between serum homocysteine levels and the prevalence of non-alcoholic fatty liver disease. In the logistic regression model adjusted for age and potential confounding parameters, the odds ratio for men was significantly higher in the uppermost quartile (model 3, quartile 4: odds ratio, 6.78; 95% confidential interval, 1.67 to 27.56); however, serum homocysteine levels in women were not associated with non-alcoholic fatty liver disease in the crude model or in models adjusted for confounders.

Conclusion

Serum homocysteine levels were associated with the prevalence of non-alcoholic fatty liver disease in men.

Citations

Citations to this article as recorded by  
  • Elevated Homocysteine is Associated With Liver Fibrosis in Metabolic Dysfunction–Associated Steatotic Liver Disease in a Sex- and Menopause-Specific Manner
    Mizuki Suzuki, Hwi Young Kim, Michael C. Reed, H. Frederik Nijhout, Allison Cruikshank, Manal Abdelmalek, Anna Mae Diehl, Paul M. Yen, Brijesh Kumar Singh, Madhulika Tripathi, Ayako Suzuki
    Gastro Hep Advances.2026; 5(1): 100800.     CrossRef
  • Homocysteine, folate, and nonalcoholic fatty liver disease: a systematic review with meta-analysis and Mendelian randomization investigation
    Shuai Yuan, Jie Chen, Lintao Dan, Ying Xie, Yuhao Sun, Xue Li, Susanna C Larsson
    The American Journal of Clinical Nutrition.2022; 116(6): 1595.     CrossRef
  • Genetic Association of Plasma Homocysteine Levels with Gastric Cancer Risk: A Two-Sample Mendelian Randomization Study
    Tianpei Wang, Chuanli Ren, Jing Ni, Hui Ding, Qi Qi, Caiwang Yan, Bin Deng, Juncheng Dai, Gang Li, Yanbing Ding, Guangfu Jin
    Cancer Epidemiology, Biomarkers & Prevention.2020; 29(2): 487.     CrossRef
  • Characterization of Early-Stage Alcoholic Liver Disease with Hyperhomocysteinemia and Gut Dysfunction and Associated Immune Response in Alcohol Use Disorder Patients
    Vatsalya Vatsalya, Khushboo S. Gala, Ammar Z. Hassan, Jane Frimodig, Maiying Kong, Nachiketa Sinha, Melanie L. Schwandt
    Biomedicines.2020; 9(1): 7.     CrossRef
  • Sex differences in risk factors for stroke in patients with hypertension and hyperhomocysteinemia
    Hui Pang, Qiang Fu, Qiumei Cao, Lin Hao, Zhenkun Zong
    Scientific Reports.2019;[Epub]     CrossRef
  • Association between homocysteine and non-alcoholic fatty liver disease in Chinese adults: a cross-sectional study
    Haijiang Dai, Weijun Wang, Xiaohong Tang, Ruifang Chen, Zhiheng Chen, Yao Lu, Hong Yuan
    Nutrition Journal.2016;[Epub]     CrossRef
  • 5,444 View
  • 52 Download
  • 9 Web of Science
  • 6 Crossref
Sociodemographic Characteristics of Underweight Korean Adults: Korea National Health and Nutrition Examination Survey, 2007-2010
Sung Il Park, Young Gyu Cho, Jae Heon Kang, Hyun Ah Park, Kyoung Woo Kim, Yang Im Hur, Hye Jin Kang
Korean J Fam Med 2013;34(6):385-392.   Published online November 25, 2013
DOI: https://doi.org/10.4082/kjfm.2013.34.6.385
Background

Underweight is associated with increased risk of mortality and morbidity. It is reported that the prevalence of underweight is increasing among Korean young women. However, there have been few studies on sociodemographic factors related to being underweight. This study was conducted to elucidate the sociodemographic characteristics of Korean underweight adults.

Methods

This study is a cross-sectional study of 7,776 adults aged 25 to 69 years using data from the Korea National Health and Nutrition Examination Survey, 2007-2010. Study subjects were composed of underweight and normal-weight adults excluding overweight adults. Body mass index was calculated from measured height and weight. Health behaviors such as smoking, drinking, and physical activity were surveyed through self-administered questionnaires, and socioeconomic status, marital status, and history of morbidity were surveyed through face-to-face interviews.

Results

Women had a higher frequency of underweight (10.4% vs. 7.0%, P < 0.001) than men. Among men, current smoking (odds ratio [OR], 1.62) and past history of cancer (OR, 2.55) were independently related to underweight. Among women, young age (OR, 2.06), former smoking (OR, 1.69), and being unmarried (OR, 1.56) were identified as independently related factors of underweight. In addition, among both men and women, alcohol drinking (men OR, 0.57; women OR, 0.77) and past history of chronic diseases (men OR, 0.55; women OR, 0.43) were independently related to a lower frequency of underweight.

Conclusion

We showed that various sociodemographic factors were associated with underweight. It was ascertained that there were differences in the sociodemographic factors related to underweight between Korean men and women.

Citations

Citations to this article as recorded by  
  • Associations between social jetlag trajectories and body mass index among young adults
    Chia-Shuan Chang, Ling-Yin Chang, Chi-Chen Wu, Hsing-Yi Chang
    SLEEP.2024;[Epub]     CrossRef
  • Maternal pre-pregnancy body mass index and related factors: A cross-sectional analysis from the Japan Environment and Children’s Study
    Yasuaki Saijo, Eiji Yoshioka, Yukihiro Sato, Yuki Kunori, Tomoko Kanaya, Kentaro Nakanishi, Yasuhito Kato, Ken Nagaya, Satoru Takahashi, Yoshiya Ito, Hiroyoshi Iwata, Takeshi Yamaguchi, Chihiro Miyashita, Sachiko Itoh, Reiko Kishi, Malshani Lakshika Pathi
    PLOS ONE.2024; 19(6): e0304844.     CrossRef
  • Association of duration of undernutrition with occurrence of tuberculosis
    Jiho Park, Ji Hyun Yoon, Hyun Kyun Ki, Yeonghee Eun, Kyungdo Han, Hyungjin Kim
    BMC Public Health.2022;[Epub]     CrossRef
  • Relationship between socioeconomic and nutritional status in the Serbian adult population: a cross-sectional study
    Jelena Gudelj Rakić, Miloš Maksimović, Janko Janković, Hristina Vlajinac, Jelena Marinković
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Associations between the Risk of Internet Addiction and Problem Behaviors among Korean Adolescents
Jisun Sung, Jungkwon Lee, Hye-Mi Noh, Yong Soon Park, Eun Ju Ahn
Korean J Fam Med 2013;34(2):115-122.   Published online March 20, 2013
DOI: https://doi.org/10.4082/kjfm.2013.34.2.115
Background

The number of internet users is increasing rapidly and internet addiction among adolescents has become a serious public health problem in Korea. In the light of behavioral addiction, this study was aimed to identify the associations between the risk of internet addiction and other problem behaviors which can lead to addiction, such as cigarette smoking, alcohol drinking, drug abuse, and sexual intercourse among a nationally representative sample of Korean adolescents.

Methods

Data from the 2010 Korean Youth Risk Behavior Web-based Survey (respondents, 73,238) were analyzed. Risk of internet addiction was assessed by the 'Korean Internet Addiction Proneness Scale for Youth-Short Form: Self Report' which was developed by the Korean National Information Society Agency in 2008. Multiple logistic regression analysis was used to calculate the odds ratios of problem behaviors among adolescents at high risk for internet addiction and adolescents at low risk for internet addiction.

Results

The odds of smoking experience, drug abuse experience, and sexual intercourse experience were significantly higher among boys at high risk for internet addiction compared to boys at low risk for internet addiction. Among girls at high risk of internet addiction, the odds of smoking experience, drinking experience, and drug abuse experience were significantly higher compared with girls at low risk of internet addiction.

Conclusion

The risk of internet addiction was associated with cigarette smoking, alcohol drinking, drug abuse, and sexual intercourse experience among Korean adolescents.

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Prevalence of Erectile Dysfunction and Utilization of Sexual Counseling in Community Family Medicine Clinics.
Yu Jang Cho, Hwan Sik Hwang, Hoon Ki Park, Jae Ghil Jeong
Korean J Fam Med 2009;30(8):617-625.   Published online August 20, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.8.617
Background
Sexual dysfunction such as erectile dysfunction (ED) may be a hidden agenda, but, it should be dealt with by family physicians in primary care. We investigated the prevalence of ED and utilization of sexual consultation practice among community family physicians. Methods: We analyzed the subjects who were males aged over 30 and married who visited 10 community family clinics around Seoul, Korea and completed questionnaires related to erectile function and utilization of sexual consultation service from May 9 to 28 2009. ED was designated if the 5-item version of international index of erectile dysfunction (IIEF-5) scores were less than 17. Results: The average age of the responders was 45.6 years. The prevalence of ED was 43.3% and increased according to age, chronic disease, low educational history and low family income. Almost all of the mild ED patients answered that they needed sexual consultation. But, half of them had no plan to have a sexual consultation. Odds ratios (ORs) with 95% confi dence intervals (CIs) for having a sexual consultation or not according to variables were calculated with logistic regression. More severe ED (OR = 0.875; 95% CI, 0.827 to 0.926), existence of chronic disease (OR = 1.828; 95% CI, 1.026 to 3.260), inferior education (OR = 0.395; 95% CI, 0.196 to 0.796), and lower income (OR = 0.326; 95% CI, 0.124 to 0.857) were the factors which infl uenced to have a sexual consultation with a family physician.Conclusion: The prevalence of ED in family clinic was over 40%, but the utilization of sexual consultations was under 50%. We need to develop intervention strategies for more sexual counseling practice according to educational history, family incomes and status of ED in community family medicine clinics.

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Insulin-like Growth Factor 1 Level and Its Relating Factor in Korean Healthy Adults.
Hyun Kook Choi, Mi Hee Kong, Byeong Hun Ahn, Sang Man Kim, Duck Ju Lee, Kwang Min Kim
Korean J Fam Med 2009;30(1):15-22.   Published online January 10, 2009
DOI: https://doi.org/10.4082/kjfm.2009.30.1.15
Background
The concern about growth hormone, used for treatment of growth hormone deficiency, wasting diseases, is increasing recently. There is much to be desired about the study for the reference range of insulin-like growth factor-1 (IGF-1) of Korean healthy adults, because there was the lack for the studies of their IGF-1 level. The authors investigated the concentration of IGF-1 according to age groups, and the correlation factor with IGF-1 level in healthy adult in Korea. Methods: The subjects were 10,681 Korean healthy adults (5,263 female, 5,418 male) aged over 20 years, who visited a Department of Family Practice and Community Health in a university hospital from March 1998 to December 2003. We excluded the persons with DM, liver disease, renal disease, thyroid disease, cancer etc. We measured the serum IGF-1, fasting glucose, lipid profile, serum albumin, protein, waist circumference, hip circumference, and body mass index. Results: IGF-1 level showed the sexual difference (184.6 ± 86.3 ng/mL for men, 178.6± 91.8 ng/mL for women) and decreased with aging significantly. Age is the most reliable correlation factor with IGF-1 (R: -0.325 for men, R:-0.463 for women). After adjusting ageand weight, IGF-1 showed the correlation with total protein, albumin, creatinin, triglyceride, HDL cholesterol for men and height, waist circumference, body mass index, waist-hip ratio, systolic blood pressure, total protein, albumin, creatinin, triglyceride, HDL cholesterol for women. Conclusion: IGF-1 concentration decreases with aging over 20 years old. It shows the strongest correlation with age in both sexes.

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  • Establishment of Reference Intervals for Serum Insulin-Like Growth Factor I in Korean Adult Population
    Boyeon Kim, Yonggeun Cho, Cheol Ryong Ku, Sang-Guk Lee, Kyung-A Lee, Jeong-Ho Kim
    Endocrinology and Metabolism.2020; 35(4): 960.     CrossRef
  • Long-term Changes in Serum IGF-1 Levels After Successful Surgical Treatment of Growth Hormone–Secreting Pituitary Adenoma
    Mi-Seon Shin, Ji Hee Yu, Jong Han Choi, Chang Hee Jung, Jenie Yoonoo Hwang, Young Hyun Cho, Chang Jin Kim, Min-Seon Kim
    Neurosurgery.2013; 73(3): 473.     CrossRef
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Perspectives of Primary Care Physicians toward Sexual History Taking in Routine Clinical Practice.
Su Hyun Kim, Young Mee Lee
J Korean Acad Fam Med 2008;29(4):269-275.   Published online April 10, 2008
Background
Physicians rarely take patients' sexual history during routine medical visit, although it would give very helpful information to reach accurate diagnosis and proper management. This survey was conducted to assess the primary physicians' perspectives towards sexual history taking and their actual behaviors on it. Methods: The survey questionnaire was made through the literature review, in-depth interview and pilot survey. We mailed this questionnaire to 400 primary care physicians who were randomly selected from the lists of internists and family physicians in Seoul and Gyunggi province and 73 of them responded. Results: The mean age of the respondents was 44.3 years. Most of them responded that sexual history is necessary only when the patients' chief complaints are directly related to sexual issues. Among the total, 94% of them answered that he or she took sexual history in less than 25% of the patients who visited his/her own clinic during last one month. The most prevalent barriers to initiate sexual history taking were fear of patients' misunderstanding about sexual harassment or intrusion into patients' personal life (60.3%) and uncertainty to conducting sexual history taking (53.4%). They thought that they were not well educated enough to take sexual history with confidence and more structured education is needed in medical schools and postgraduate residency training. Conclusion: Sexual history seemed not to be taken by primary care physicians as a routine medical practice and physicians showed rather passive attitude. Beneficial effects of sexual history taking on patients' management and related communication skills should be emphasized and systematically educated. (J Korean Acad Fam Med 2008;29:269-275)
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Factors Related to Increase of Blood Pressure in Obese Children and Adolescents.
Sang Hyun Lee, Eunju Sung, Ho Cheol Shin, Yong Woo Park, Cheol Hwan Kim, Kyung Seop Soh
J Korean Acad Fam Med 2007;28(7):515-522.   Published online July 10, 2007
Background
As obese population is increasing nowadays, research on blood pressure of obese children is being performed more frequently. However, there are only few research related to factors about blood pressure among obese children in Korea. The purpose of this study was to analyze the factors affecting blood pressure of obese children and adolescents. Methods: The subjects were elementary and middle school students diagnosed with obesity (n=1716). Height, weight, waist circumstance, body fat percent, blood pressure were measured. Family history and sexual maturity were investigated through the questionnaire. The relationship between the factors and the increase of blood pressure was analyzed. Results: Body weight was the most powerful factor among to factors related to increase of blood pressure (male r=0.45, P<0.05, female r=0.37, P<0.05). Also, height, percentage weight for height (PWH), body mass index (BMI) and waist circumference was correlated with the blood pressure. In multiple regression analysis, family history of hypertension and the sexual maturity were significant determinants of blood pressure in males after adjusting for weight. However, body fat percent was a significant determinant in females. Conclusion: Body weight was the most important factor which increased the blood pressure in obese children and adolescents in both sexes. But males and females had different factors related to the increase of blood pressure with the exception of body weight. (J Korean Acad Fam Med 2007;28:515-522)
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Patients' Attitudes toward Proactive Screening for Sexual Dysfunction.
Dong Wook Shin, Jong Seung Kim, Kang San Jung, Cheol Min Lee, Jae Kyung Choi, Min Su Park, Dae Hyun Yoon, Bong Yul Huh
J Korean Acad Fam Med 2006;27(8):637-644.   Published online August 10, 2006
Background
: Although proactive screening for sexual dysfunction in primary care has been emphasized as an important part of comprehensive care, doctors seldom ask their patients about their sexual function. Worry about patients' responses was reckoned as a major barrier, but few studies have dealt with how patients feel and what they want. This study was aimed to describe and analyze the attitudes of patients toward proactive screening for sexual dysfunction.

Methods : A set of self-administered questionnaire was given to every patients who visited a family medicine clinic in a university hospital for 2 weeks from March 16, 2005.

Results : A total of 185 patients were analyzed. Among them, 72.4% were willing to consult their physician when they were in trouble with their sexual function, and 84.3% said proactive screening for sexual dysfunction was necessary. Many patients did not care about 'when to be asked' and wanted to be asked in face-to-face interview rather than by a questionnaire. Sentence emphasizing that every patient is given the same question was most preferred.

Conclusion : Patients' attitude toward proactive screening for sexual dysfunction in primary care was generally positive. Patients preferred to be asked ;I ask every patient about his sexual problem. If you're OK, I ask you about your sexual problem.; regardless of timing, during the interview.
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Serum Homocysteine and Its Relevant Factors among Health Screeners in a University Hospital.
Dong Kuk Lee, Hyun Kook Choi, Jung Cheon Son, Yoo Ji Chung, Bom Taeck Kim, Kwang Min Kim
J Korean Acad Fam Med 2005;26(11):671-679.   Published online November 10, 2005
Background
: Elevated plasma total homocysteine is a risk factor for cardiovascular diseases. The authors investigated the parameters such as habit, body index, cardiovascular risk factors, nutrition relative to the plasma homocysteine concentration.

Methods : The subjects were 6,223 adults (3,377 males, 2,846 females) who were over 18 years of age and visited a health promotion center of a university hospital from March 2002 to January 2003. We assessed the relationship between the homocysteine level and the following parameters: sex, age, weight, body mass index, waist circumference, smoking, alcohol, systolic and diastolic blood pressure (BP), triglyceride, total cholesterol, high density lipoprotein cholesterol, creatinine, albumin and hemoglobin.

Results : The homocysteine levels was 10.5±5.9μmol/L in males, 7.3±2.6μmol/L in female. Thus it was significantly higher in males (P<0.001). After adjusting for variables that affect the homocysteine, the subjects over the age of 54 showed 10.7μmol/L (9.5, 12.0, 95% Confidence Interval), which was significantly (P=0.002) higher than the below the age of 38 groups 8.5μmol/L (7.8, 9.2, 95% CI). Non-smoking group showed 8.6μmol/L (8.4, 8.9, 95% CI), while over 28 pack-year group showed 9.6μmol/ L (9.2, 10.0, 95% CI), which was significantly (P<0.001) higher than the non-smoking groups. For the group with systolic BP over 132mmHg, it was 9.3μmol/L (8.8, 9.5, 95% CI). This was significantly (P=0.004) higher than 8.7μmol/L (8.4, 9.0, 95% CI) in the group whose systolic BP was less than 108 mmHg. The homocysteine was 10.4μmol/L (10.1, 11.7, 95% CI) for the group with creatinine over 1.0 mg/dL, which was significantly (P<0.001) higher than 7.9μmol/L (7.6, 8.2, 95% CI) in the group whose creatinine was less than 0.8 mg/dL.

Conclusion : After adjusting for variables that affect the homocysteine, significant difference in its values was found between males and females. The homocysteine was significantly increased in the group whose age, systolic BP, amount of smoking, and creatinine were higher.
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Family Physician as a Counsellor Focused on Sexual and Family Problems: Cheonan Practice-Based Research Network Study.
Seong Hee Jin, Yoo Seock Cheong, Eal Whan Park, Eun Young Choi, Sun Mi Yoo, Eun Kyung Kim, Ki Sung Kim, Yun Jong Park, Hung Tag Yeoum, Hye Weon Jung, Jong Min Lee, Guwang Hwy Kim
J Korean Acad Fam Med 2004;25(4):322-328.   Published online April 10, 2004
Background
: The primary concern of a family physician is the healthcare of patients and their families, with the patient's disease itself being secondary. Family physicians should make efforts to discuss personal issues with their patients. This study examined how many patients were counseled about their private problems, especially family or sexual issues in the private clinics of Cheonan.

Methods : The subjects were the patients who visited a practice-based network from April to June in 2003. The data were collected through simple questionnaire about sociodemographic features of patients and their family and sexual problems.

Results : Eighty eight patients were studied for a total of 107 cases that consisted of 67 cases of family problems (62%) and 40 cases of sexual matters (38%). The common issues about family problems were `the partners' (23 cases, 21%) and `the patients` children' (29 cases, 27 %). The most frequent sexual problems were 'sexually transmitted diseases' (13 cases, 32.5%), `impotence' (7 cases, 17.5%), 'loss of libido, and unsatisfaction' (6 cases, 15.0%). Most physicians were involved in family and sexual issues with medications, and simple counseling with reassurance. Simple counseling was given for 14 cases (21.0%) for family issues and 18 cases (44.0%) for sexual issues. The patients were treated with medications in 47 cases (70.0%) for sexual and 15 cases (38.0%) for family problems.

Conclusion : The most common issue for family problems was their partners and for sexual problems was 'sexually transmitted diseases'. Most family physicians were involved with both simple counseling and medications.
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The Positive Rate of Serum Rheumatoid Factor in Health Screening Subjects and Related Factors.
Jae Soon Song, Kyoung Ho Eom, Jong Bum Park, Won Duk Kim, Seoung Ho Han, Joo sung Park
J Korean Acad Fam Med 2004;25(2):126-132.   Published online February 10, 2004
Background
: This study was done to estimate the prevalence of Rheumatoid Factor
(RF) positive rate in adult Korean population and to investigate the association between
rheumatoid factor positive rate and related factors.

Methods : The database from 4,678
subjects, who visited a general health screening center of an university hospital during 1 year
period were surveyed. RF was tested using a commercial latex test kit, HBsAg by RIA of 3rd
generation, anti-HCV by EIA of 3rd generation and serum AST, ALT by enzyme kinetic meth
od. Syphilis was checked using RPR test and TPHA. Lung diseases (tuberculosis, IPF) were
screened using chest X-ray. Flukes was checked by sedimentation method and cestodes was
by direct method in stool tests. Smokers were based on history on health screening.

Results :
1) The positive rate of RF was 4.4%, HBsAg was 5.9%, anti-HCV was 1.5% and ALT>35 IU/L
was 18.4%. The number of syphilis subjects was 19, lung diseases was 119, parasitic diseases
was 43, and smokers was 1,299. 2) RF positive rate of males was 4.0%, females was 5.3%.
Therefore, the positivity of females was higher than males and RF positivite rate was increased
in the higher age groups. 3) RF positive rate in HBsAg (+) subjects was 18.1% and HBsAg
(-) was 3.6% and in anti-HCV (+) subjects was 10.3% and anti-HCV (-) was 4.3%. 4) RF
positive rate of subjection both positive reactions of RPR test and TPHA, namely, syphilis tests
was 21.1%. 5) RF positive rate of parasitic diseases was 4.7%, lung diseases was 2.5% and
smokers was 4.2%. 6) RF positive rate was highly associated with HBsAg, syphilis, anti-HCV,
female sex, age in order of sequence.

Conclusion : The positive rate of RF in healthy Korean
adults can be estimated to be 4.5% and shows high association with hepatitis B and C virus
infection in addition to syphilis, age and sex.
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Identification of Related Factors of Female Sexual Function in Family Medicine Outpatients.
Sang Yeon Suh, Taek Soo Shin, Taiwoo Yoo, Bong Yul Huh
J Korean Acad Fam Med 2003;24(8):721-730.   Published online August 10, 2003
Background
: Female sexual function is influenced by much more factors than that of male and has a close relationship with psychosocial factors. A satisfying sex life has a high correlation to a happy married life. A questionnaire provides easy access to private matters and in a multidimensional manner. The objective of this study was to identify the factors related to female sexual function to help sexual adjustment in marriage.

Methods : A hundred married women living with their spouses, who visited an outpatient clinic of family medicine department of a university hospital in Seoul were studied. After filling out the self-administered questionnaire, a face-to-face interview was done on all study subjects. For multivariate analysis of the related factors, the outcome variables were a binary response of the normal female sexual cycle ?drive, lubrication, orgasm, and satisfaction.

Results : The multivariate analysis showed that the household income was a significant factor related to Drive (Odds Ratio: OR=0.6, 95% Confidence Interval: CI 0.4∼0.9). Age was a significant factor related to Insufficient Lubrication (OR=1.1, 95% CI 1.0∼1.3). Insufficient foreplay was a risk factor for Insufficient Lubrication (OR= 2.4, P=0.052). In multivariate analysis of the Orgasm related factors, the perceived health status showed an OR of 7.1 (95% CI 1.5∼32.6) and both marital satisfaction and open communication showed an OR of 6.0 (95% CI 1.3∼26.8) and an OR of 5.8 (95% CI 1.2∼28.2), respectively. The significant related factors to Satisfaction were in order of importance of sex life, education, and open communication, with an OR of 3.6 (95% CI 1.7∼7.6), 2.5 (95% CI 1.1∼5.9), and 2.0 (95% CI 1.0∼3.8), respectively.

Conclusion : The positively related factors to female sexual function were good perceived health status, high marital satisfaction, placing importance in sex life, and open communication regarding sexual matters. Increasing age and household income were found to be factors adverse to female sexual function.
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The Development of Female Sexual Function Questionnaire in Family Medicine Outpatients.
Sang Yeon Suh, Tai Woo Yoo, Bong Yul Huh
J Korean Acad Fam Med 2003;24(2):172-182.   Published online February 10, 2003
Background
: Currently, the high quality of life associated with women's rights is strongly supported and has become an important social issue. As a result, there is an increasing need for studies concerning female sexual function. The objectives of this study was to develop a questionnaire to evaluate sexual function evaluation in Korean women.

Methods : A total of 100 married women, who visited an outpatient clinic of family medicine department of a university hospital in Seoul, were studied. After filling out the self-administered questionnaire, a face-to- face interview was done on all study subjects. The items of this questionnaire were adopted from questionnaires with proven validity and reliability. Factor analysis was done and Crohnbach's alpha was calculated.

Results : The items of this questionnaire were classified into 5 parts: Drive, Excitement, Sexual activity, Satisfaction, and Spouse. The total variance was 51.5%. The total Crohnbach's alpha was 0.82. The internal consistency was high. Study subjects were able to complete this questionnaire within 10 minutes.

Conclusion : The validity and reliability of this female sexual function questionnaire was found to be acceptable. This questionnaire can be utilized as a diagnostic adjunctive tool and feedback for treatment through further studies.
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A Study on the Validity of a Single-Item Question Concerning Sexual Satisfaction as a Screening Tool for Erectile Dysfunction in Primary Care.
Young Ho Sung, Su Jin Kim, Young Sik Kim
J Korean Acad Fam Med 2002;23(11):1334-1339.   Published online November 10, 2002
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The association of obesity with erectile dysfunction.
Jung Ho Han, Seok Woo Ryu, Hyun Ho Kim, Sang Yeoup Lee, Yun Jin Kim
J Korean Acad Fam Med 2001;22(7):1112-1118.   Published online July 1, 2001
Background
: Many studies have shown that obesity is associated with sexual dysfunction and causes erectile dysfunction particularly, but these studies are mainly about chronic diseases caused by obesity. Therefore, we conducted a study to evaluate the association of obesity in itself with erectile dysfuntion.

Methods : The study sample consisted of men, aged over 20 who visited in a university hospital in Pusan from December 1999 to March 2000, who responded to the Korean version of the international index of erectile function(IIEF). The patients having obesity-related diseases were excluded from the subject group. The subjects were classified into 'obese', 'normal' group according to body mass index(BMI) and erectile function was classified into 'erectile dysfunction', 'normal' according to IIEF-5 score. Chi-square test and Fisher's exact test were performed for statistic analysis.

Results : The mean age was 42.1. In total 160 subjects. 109 men(68.1%)belonged to the normal group and 51(31.9%) to the obese group. and 100 men(62.5) had erectile dysfunction. In normal group, 43(39.4%) had normal erectile function and 66(60.6%) and erectile dysfunction. In obese group, 17(3.3%) were normal and 34(66.7%) had erectile dysfunction. No significant difference between two groups was noted in erectile function (P>0.05).

Conclusion : There was no significant association of obesity in itself with erectile dysfunction in this study after excluding effects of other obesity-related problems.
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Sexuality and its influential factors in old women.
Suk Kyung Lee, Sam Huy Choi, Tae Ki Chun, Hyun shil Kim, Sung Hwa Kim
J Korean Acad Fam Med 2001;22(3):386-396.   Published online March 1, 2001
Background
: Although sexuality in old women is important for the quality of life, that has been overlooked due to social indifference. Because the studies for sexuality in old women were lack in Korea, we surveyed sexuality and its influential factors in old women.

Methods : From March to July 2000, we surveyed 115 old women over 60 years with 22 items of questionnaire. Data were gathered through written responses to the questionnaire and one to one interview between doctor and subject. Statistical analysis was done with SPSS ver10.0/PC+ and its significance was tested by chi-square(P<0.05).

Results : Mean age of 115 women is 64.84±4.54 years. There are 80 cases (69.6%) that thought sexuality is important in old women. Sexuality and sexual interest get gradually decreased by aging. Marital state, age of husband, family structure, economic state, sexual interest are statistically significant as the influential factors of sexuality (P<0.05). Sexual satisfaction comes out 35.7%. Age, marital state, family structure, job, economic state, subjective health state, current medication, sexual interest are statistically significant as the influential factors of sexual satisfaction(P<0.05). The reasons of decreased sexuality is due to aging process(47.8%), no partner(17.4%), partner problem(14.8%), physical illness(10.4%) and decreased libido.

Conclusion : We conclude that sexuality in old women is important. Its influential factors are marital state, age of husband, family structure, economic state, sexual interest. Age, marital state, family structure, job, economic state, subjective health state, current medication, sexual interest are statistically significant as the influential factors of sexual satisfaction.
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Bone mineral density and sex steroids in middle aged men.
Han Jin Oh, Ki Nam Nam
J Korean Acad Fam Med 2000;21(2):154-162.   Published online February 1, 2000
Background
: Osteoporosis is a skeletal condition that is characterized by reduction in bone volume and an increased vulnerability to fracture, practically of the proximal femur and vertebrae. But the etiology of osteoporosis in most men without history of alcohol abuse, or glucocorticoid excess in unknown. Several studies revealed that bone density in aged men was associated with serum sex steroids or sex hormone binding globulin (SHBG).

Methods : We have analyzed bone density and sex steroids, and SHBG of healthy 100 middle aged men who visited one university hospital located in Taejon city from Jan. 1997 to Nov. 1997. Aim of this study as to determine whether bone density in middle aged men was associated with serum sex steroids or SHBG.

Results &

Conclusion : Body mass index was significantly associated with serum FEI. BMI also associated negatively with SHBG. Bone density at lumbar spine was significantly positively associated with FEI (Free Estradiol Index) (r=0.359, P<0.001). SHBG was negatively associated (r=-0.273, P<0.01) with lumbar bone mineral density. After controlling for age, FEI and SHBG were still associated with BMD of lumbar spine. Because of these associations, multiple stepwise regression models were constructed, and accounted for 12-17% of the variability in bone density. Also, these results showed consistent, significant positive associations between bone density and FEI, BMI in middle aged men. Therefore, our data suggest that FEI and BMI may play an important role in the maintenance of the male skeleton.
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