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"Spirometry"

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"Spirometry"

Original Articles
Association of Lung Function with Serum 25-Hydroxyvitamin D Level according to the Presence of Past Pulmonary Tuberculosis in Korean Adults
Min Sung Kim, Chang-Jin Choi, Kyung Min Kwon, Kyung-Soo Kim, Whan-Seok Choi, Yoon Jee Oh
Korean J Fam Med 2019;40(2):93-99.   Published online December 4, 2018
DOI: https://doi.org/10.4082/kjfm.17.0083
Background
Vitamin D deficiency is associated with an increased risk of pulmonary tuberculosis (PTB) infection and the treatment outcome. The aim of this study was to examine the relationship between the serum 25-hydroxyvitamin D (25[OH]D) level and lung function in Korean adults according to whether or not there is a history of PTB.
Methods
The data for subjects aged 19 years or older from the Korea National Health and Nutrition Examination Survey 2008–2012 who underwent spirometry, chest radiography, and serum 25(OH)D level measurement were analyzed.
Results
Evidence of past PTB infection was found in 1,482 (9.6%) of 15,516 subjects. The serum 25(OH)D level was lower in the group with past PTB than in the non-PTB group (P=0.013). Respiratory dysfunction was more common in the past PTB group than in the non-PTB group (restrictive pattern, 14.0% vs. 9.6%; obstructive pattern, 29.6% vs. 8.2%; both P<0.001). After adjusting for age, sex, height, and season, the mean difference in forced expiratory volume in 1 second (FEV1) between the highest and lowest quartiles of 25(OH)D was 100.2 mL (standard error=49.3 mL, P for trend=0.049) in the past PTB group and 34.7 mL (standard error=13.6 mL, P=0.009) in the nonPTB group.
Conclusion
FEV1 tended to increase as the vitamin D quartile increased in both study groups. This relationship was more pronounced in subjects with a history of PTB. A higher serum 25(OH)D level might be beneficial in preserving lung function after PTB infection.

Citations

Citations to this article as recorded by  
  • Post-pulmonary tuberculosis lung function: a systematic review and meta-analysis
    Sharina Ratnakumar, Sally E Hayward, Emma K Denneny, Lucy P Goldsmith, Rebecca Evans, William Checkley, Delia Goletti, Catherine W M Ong, Mateusz Gotowiec, Junkai Zhu, Jon S Friedland, Joanna C Porter
    The Lancet Global Health.2025; 13(6): e1020.     CrossRef
  • Post-tuberculosis lung impairment: systematic review and meta-analysis of spirometry data from 14 621 people
    Olena Ivanova, Verena Sophia Hoffmann, Christoph Lange, Michael Hoelscher, Andrea Rachow
    European Respiratory Review.2023; 32(168): 220221.     CrossRef
  • Associating the blood vitamin A, C, D and E status with tuberculosis: a systematic review and meta-analysis of observational studies
    Fei Xu, Baolan Ma, Dandan Wang, Jialin Lu, Ke Xiong, Jinyu Wang
    Food & Function.2022; 13(9): 4825.     CrossRef
  • Effectiveness of Maternal Vitamin D Supplementation in Preventing Respiratory Tract Infections in Children
    Soo Young Kim
    Korean Journal of Family Medicine.2022; 43(3): 155.     CrossRef
  • Decreased lung function is associated with vitamin D deficiency in apparently health, middle aged Koreans: the Kangbuk Samsung Health Study
    Jonghoo Lee, Hye Kyeong Park, Min-Jung Kwon, Soo-Youn Ham, Si-Young Lim, Jae-Uk Song
    European Journal of Clinical Nutrition.2021; 75(3): 501.     CrossRef
  • 6,073 View
  • 91 Download
  • 5 Web of Science
  • 5 Crossref
The Association of Lung Age with Smoking Status in Korean Men
Hye Young Oh, Hong Soo Lee, Sang Wha Lee, Kyung Won Shim, Hyejin Chun, Joo Yeon Kim
Korean J Fam Med 2014;35(1):35-41.   Published online January 23, 2014
DOI: https://doi.org/10.4082/kjfm.2014.35.1.35
Background

Lung age, calculated from sex, forced expiratory volume in one second (FEV1), and height, was developed to illustrate premature changes to the lungs and could be used to motivate smoking cessation. However, this method has not been tested in association with smoking in Korea. The purpose of this study was to investigate the association of lung age with smoking and other factors in Korean males.

Methods

We reviewed the records of 1,100 healthy men who visited a health promotion center at Ewha Womans University Medical Center from January 2008 to June 2009. Lung age was calculated from FEV1 and normal predictive values of spirometry according to age in the Korean population. The difference between lung age and chronological age was evaluated in relation to smoking status, weight, body mass index, waist, muscle mass, fat mass, and exercise.

Results

The age difference was significantly higher in current smokers than in non-smokers (12.47 ± 19.90 vs. 7.30 ± 19.52, P < 0.001). Additionally, the age difference was positively correlated with life time pack-year (β = 0.223; P < 0.001) and fat mass (β = 0.462; P < 0.001). Lung age increased 1 year for 4.48 pack-year increase or for 2.16% increase in fat mass.

Conclusion

We found a significant relationship between lung age and both smoking status and fat mass in healthy Korean males. Lung age may be a useful tool for motivating cessation of cigarette smoking and management of risk factors related to obesity.

Citations

Citations to this article as recorded by  
  • Developing a predictive equation of muscular age to evaluate muscle health in Chinese community-dwelling older women
    Xiaoguang Zhao, Jiabin Yu, Nan Liu
    Health Care for Women International.2023; 44(12): 1587.     CrossRef
  • Effect of smoking status on spirometric lung age in adult Chinese Men
    Xiaoguang Zhao, Chenya Du
    Health & Social Care in the Community.2022; 30(4): 1384.     CrossRef
  • Comparison of periodontal status and salivary IL-15 and -18 levels in cigarette-smokers and individuals using electronic nicotine delivery systems
    Dena Ali, Isaac Kuyunov, Jagan Kumar Baskaradoss, Toshinari Mikami
    BMC Oral Health.2022;[Epub]     CrossRef
  • A pilot randomized controlled trial on the effectiveness of a ‘lung age’ intervention on smoking cessation: study protocol
    Imran Muhammad, Wenqi Mok, Hai Moy Toh, Daniel Sii, Wenru Wang
    Journal of Advanced Nursing.2015; 71(10): 2426.     CrossRef
  • 4,558 View
  • 42 Download
  • 10 Web of Science
  • 4 Crossref
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