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Original Articles

Factors Associated with Sleep Disorder among Korean Cancer Survivors: A Cross-Sectional Study
Hyeonjin Cho, Wonyoung Jung, Dong Wook Shin, Jinyoung Shin, Yun-Mi Song
Korean J Fam Med 2023;44(4):224-233.   Published online July 18, 2023
DOI: https://doi.org/10.4082/kjfm.22.0159
Background
The factors associated with sleep disorder are controversial. This study aimed to evaluate the prevalence of sleep disorder and the factors associated with sleep disorder among Korean adult cancer survivors.
Methods
In this cross-sectional study, we collected data on sleep problems as outcome variables, and sociodemographic and clinical information as predictor variables from cancer survivors at two university-affiliated hospitals. Sleep disorder was defined as “a difficulty in sleep initiation or sleep maintenance at least 3 times a week that started after a cancer diagnosis.” Multiple logistic regression analysis was performed with odds ratios (OR) and 95% confidence intervals (95% CI) to evaluate the factors associated with sleep disorder.
Results
The participants were 1,893 Korean cancer survivors (mean age, 58.1 years; females 68.0%). The prevalence of sleep disorder among male and female cancer survivors were 16.5% and 20.3%, respectively. An increase of age by 1-year was associated with a 1.04 (95% CI, 1.01–1.07; P=0.011) times higher risk of sleep disorder in males, while an inverse association was found in females. In female survivors, high fear of cancer recurrence (FCR), high anxiety, menopause, and high EuroQol Visual Analog Scale were associated with 1.45 (95% CI, 1.06–1.98; P=0.020), 1.78 (95% CI, 1.25–2.55; P=0.002), 1.70 (95% CI, 1.08–2.67; P=0.022), and 0.59 (95% CI, 0.43–0.82; P=0.002) times higher risk of sleep disorder, respectively. In male survivors, living with a spouse/or partner was associated with 57% (95% CI, 0.20–0.95; P=0.036) lower risk of sleep disorder. Analyses of cancer sites showed that the factors associated with sleep disorder varied across cancer sites.
Conclusion
One-fifth of adult cancer survivors had sleep disorder. Age, menopausal status, FCR, anxiety, living with a spouse or partner, and quality of life were independently associated with sleep disorder in Korean cancer survivors.

Citations

Citations to this article as recorded by  
  • Social support, fear of cancer recurrence and sleep quality in breast cancer: A moderated network analysis
    Yingting Jiang, Xinyu Wu, Hongman Li, Ying Xiong, M. Tish Knobf, Zengjie Ye
    European Journal of Oncology Nursing.2025; 74: 102799.     CrossRef
  • Subgroups of sleep quality and associated risk factors in patients with cancer undergoing radiotherapy: A cross-sectional study based on latent profile analysis
    Liuna Bi, Xian Zhang, Linlin Wang, Yanxiu Cai, Jing Han
    European Journal of Oncology Nursing.2024; 68: 102488.     CrossRef
  • 2,864 View
  • 147 Download
  • 2 Web of Science
  • 2 Crossref
Association between Complementary and Alternative Medicine Use and Fear of Cancer Recurrence among Breast Cancer Survivors
Esther Eun Hwa Kim, Jihun Kang
Korean J Fam Med 2022;43(2):132-140.   Published online March 17, 2022
DOI: https://doi.org/10.4082/kjfm.20.0158
Background
This study aimed to evaluate the association between complementary and alternative medicine (CAM) use and fear of cancer recurrence (FCR) among breast cancer survivors, using a validated multidimensional FCR-assessing instrument. Despite the debate over its medical effects, the use of CAM in breast cancer survivors is increasing.
Methods
We recruited 326 breast cancer survivors who had completed the primary cancer treatment. Information on CAM use was obtained using a self-administered questionnaire, and FCR was assessed using the Korean version of the FCR Inventory (FCRI). Multivariate linear regression analysis was performed to evaluate the association between CAM use and FCR.
Results
CAM users had higher total FCR scores than CAM non-users after covariate adjustment (CAM users: 74.6 vs. CAM non-users: 68.7; P=0.047). Among the FCRI subscales, CAM users showed higher coping strategy scores (CAM users: 22.3 vs. CAM non-users: 20.6; P=0.034) in the multivariable adjusted analysis. The use of multiple types of CAM was associated with increased FCR in a dose-dependent manner (P=0.002).
Conclusion
Breast cancer survivors who used CAM had a higher FCR than CAM non-users. The dose-response relationship between the use of multiple types of CAM and FCR suggests that breast cancer survivors who use multiple types of CAM should be provided with appropriate psychological interventions to decrease FCR.

Citations

Citations to this article as recorded by  
  • Critical Considerations Regarding the Article “Association between Complementary and Alternative Medicine Use and Fear of Cancer Recurrence among Breast Cancer Survivors”
    Niloufar Johari Varnoosfaderani, Ehsan Amiri-Ardekani
    Korean Journal of Family Medicine.2023; 44(1): 66.     CrossRef
  • Use of complementary and alternative medicine for reducing fear of cancer recurrence among cancer survivors: Does it work?
    Heliang Wu, Adnan Rashid Aziz, Mahlagha Dehghan, Leyla Ahmadi Lari, Rasmieh Al-Amer, Mohammad Ali Zakeri
    Asia-Pacific Journal of Oncology Nursing.2023; 10(10): 100278.     CrossRef
  • Adherence to lifestyle recommendations among Norwegian cancer survivors and the impact of traditional and complementary medicine use: the Tromsø Study 2015–2016
    Kiwumulo Nakandi, Faith O. Benebo, Laila A. Hopstock, Trine Stub, Agnete E. Kristoffersen
    BMC Complementary Medicine and Therapies.2023;[Epub]     CrossRef
  • 4,204 View
  • 77 Download
  • 3 Web of Science
  • 3 Crossref
The Association between the Use of Dietary Supplement and Psychological Status of Cancer Survivors in Korea: A Cross-Sectional Study
Han Rim Lee, Yun-Mi Song, Keun Hye Jeon, In Young Cho
Korean J Fam Med 2021;42(4):317-326.   Published online July 20, 2021
DOI: https://doi.org/10.4082/kjfm.20.0184
Background
Dietary supplements (DS) use is known to be common among cancer survivors. However, detailed information on the factors influencing DS use seems insufficient, including cancer-related and psychological factors.
Methods
Study subjects were 1,852 Korean adult cancer survivors recruited from cancer survivor clinic of two university-affiliated hospitals. Data were collected retrospectively through review of medical records and self-administered questionnaires. Psychological factors were assessed using Hospital Anxiety and Depression Scale (HADS) and Fear of Cancer Recurrence Inventory-Short Form. Factors associated the DS use were evaluated by multiple logistic regression analysis after adjusting for covariates.
Results
The prevalence of long-term DS use was 15.7% in overall (17.5% in female and 11.6% in male). Female survivors were 3.14 times (95% confidence interval [CI], 1.89–5.22) more likely to use DS than male. In male cancer survivors, ever-smoking and previous radiotherapy were positively associated with DS use. In females, breast cancer survivors were 0.32 times less likely to use DS compared with stomach cancer survivors, and survivors with family history of cancer were 1.39 times more likely to use DS than those without. After adjusting for sociodemographic, clinical, and lifestyle factors, survivors with anxiety (HADS ≥8) used DS 1.38 times (95% CI, 1.01–1.91) more frequently, compared with those without anxiety.
Conclusion
Diverse factors such as female sex, cancer treatment modality, smoking history, family history and anxiety status were associated with DS use in Korean cancer survivors. Targeted strategies with consideration of these factors are needed for counseling DS use for cancer survivors.

Citations

Citations to this article as recorded by  
  • Exploring men’s cancer journeys in Norway: a comprehensive survey on diet, supplements, and use of complementary and alternative therapies
    Agnete E. Kristoffersen, Kiwumulo Nakandi, Arne Johan Norheim, Mona Bjelland, Jorunn V. Nilsen, Eran Ben-Arye
    BMC Complementary Medicine and Therapies.2025;[Epub]     CrossRef
  • Supplement use and its impact on daily life of cancer patients: a cross-sectional study
    Youssef El Toum, Tarek Costa, Elissa El Toum, Tina Haddad, Pascale Salameh, Fady El karak, Marwan Ghosn, Fady Nasr, Georges Chahine, Joseph Kattan, Hampig Raphael Kourie
    Supportive Care in Cancer.2024;[Epub]     CrossRef
  • Factors Associated with Long-Term Dietary Supplement Use among Korean Breast Cancer Survivors: A Cross-Sectional Study
    Seonghye Kim, Yohwan Yeo, Jinyoung Shin, Dong Wook Shin, Belong Cho, Yun-Mi Song
    Nutrients.2023; 15(18): 4087.     CrossRef
  • Addressing Patient Requests to Add Dietary Supplements to Their Cancer Care—A Suggested Approach
    Moshe Frenkel, Meroe B. Morse, Santhosshi Narayanan
    Nutrients.2023; 15(24): 5029.     CrossRef
  • Differences in the Perception of Dietary Supplements between Dietary Supplement/Medicine Users and Non-Users
    Tsuyoshi Chiba, Nanae Tanemura
    Nutrients.2022; 14(19): 4114.     CrossRef
  • The Self-Administered Use of Complementary and Alternative Medicine (CAM) Supplements and Antioxidants in Cancer Therapy and the Critical Role of Nrf-2—A Systematic Review
    Paula Krejbich, Marc Birringer
    Antioxidants.2022; 11(11): 2149.     CrossRef
  • 4,654 View
  • 99 Download
  • 6 Web of Science
  • 6 Crossref
Background
This study aimed to investigate trends in the prevalence of current smokers and motivation to quit among Korean male cancer survivors.
Methods
Out of 20,012 men who participated in the Korea National Health and Nutrition Examination Survey V (2010–2012), VI (2013–2015), and VII (2016–2017), 742 cancer survivors were included. A cancer survivor was defined as a person who concurred to the item, “The cancer has been diagnosed by a doctor” in the health questionnaire. Smoking status was classified as current, former, and never smokers. Regarding motivation to quit smoking, we defined those who had a willingness to quit within 6 months as the willing group. Logistic regression analysis was conducted to examine trends in the prevalence of current smokers and the proportion of the willing group among current smokers.
Results
Overall, 3.7% of Korean men who participated in the study were cancer survivors. Current smokers constituted 19.5%, 19.1%, and 15.3% of cancer survivors in phases V, VI, and VII respectively which did not show significant changes (P for trend=0.33). However, the proportion of current smokers in the non-cancer group was significantly reduced to 46.6%, 41.2%, and 38.9% in phases V, VI, and VII, respectively (P for trend <0.001). The proportion of those with a motivation to quit smoking did not show a significant trend in the cancer survivors (P for trend=0.964) and non-cancer group (P for trend=0.884).
Conclusion
Prevalence of current smokers and motivation to quit in Korean male cancer survivors did not show significant trends.

Citations

Citations to this article as recorded by  
  • Current status of health promotion in Korea
    Soo Young Kim
    Journal of the Korean Medical Association.2022; 65(12): 776.     CrossRef
  • Smoking Cessation in Cancer Survivors
    Young Gyu Cho
    Korean Journal of Family Medicine.2021; 42(4): 258.     CrossRef
  • 4,580 View
  • 84 Download
  • 2 Web of Science
  • 2 Crossref
Background
Cancer survivors experience decreased physical function and reduced muscle strength, which leads to lower quality of life (QOL). The hand grip strength (HGS) can be a predictor of poor health-related QOL as a parameter of sarcopenia. The purpose of this study was to investigate the relationship between low HGS and QOL in cancer survivors and healthy controls.
Methods
We analyzed 392 cancer survivors and 1,176 healthy controls from the Korea National Health and Nutrition Examination Survey, 2014–2017. We defined low HGS as 2 standard deviation values for healthy young Korean adults from a previous study. QOL was evaluated using the European Quality of Life Scale-Five Dimensions. A complex sample logistic regression model was used to assess the relationship between each dimension of low HGS and QOL.
Results
The odds ratios (ORs) for decreased QOL were significantly higher in male cancer survivors with low HGS on self-care (OR, 8.51; 95% confidence interval [CI], 1.69–42.83) and usual activities (OR, 6.63; 95% CI, 1.22–36.03). The ORs for problems in mobility (OR, 5.87; 95% CI, 2.04–16.91), usual activities (OR, 14.46; 95% CI, 3.84–54.44), pain/discomfort (OR, 4.90; 95% CI, 2.00–12.01), and anxiety/depression (OR, 6.43; 95% CI, 2.16–19.12) were significantly high in female cancer survivors with low HGS. However, healthy controls showed no significant relationship between low HGS and QOL.
Conclusion
For cancer survivors, low HGS was associated with poor QOL in some domains. Strategies to increase muscle strength must be considered to improve the QOL of cancer survivors.

Citations

Citations to this article as recorded by  
  • The quality of life impacting factors in malnourished patients with gastric cancer
    Hong Zhao, Chenan Liu, Guotian Ruan, Xin Zheng, Yue Chen, Shiqi Lin, Xiaoyue Liu, Jinyu Shi, Xiangrui Li, Shuqun Li, Hanping Shi
    Frontiers in Oncology.2024;[Epub]     CrossRef
  • Cardiovascular and metabolic determinants of quality of life in patients with cancer
    Ruben Evertz, Katharina Gödde, Christine Diehl, Miroslava Valentova, Tania Garfias‐Veitl, Friederike Braulke, Gerald G. Wulf, Tobias R. Overbeck, Annalen Bleckmann, Alexander O. König, Pia Weinländer, Sophia Potthoff, Sara Hadzibegovic, Alessia Lena, Ulri
    ESC Heart Failure.2023; 10(1): 167.     CrossRef
  • Understanding Heterogeneity in the Relationship Between Cancer and Hand Grip Strength: A Longitudinal Analysis
    Jinho Kim, Gum-Ryeong Park
    Research on Aging.2023; 45(7-8): 586.     CrossRef
  • Better Handgrip Strength Is Related to the Lower Prevalence of Pain and Anxiety in Community-Dwelling Older Adults
    Natalia Sosowska, Agnieszka Guligowska, Bartłomiej Sołtysik, Ewa Borowiak, Tomasz Kostka, Joanna Kostka
    Journal of Clinical Medicine.2023; 12(11): 3846.     CrossRef
  • Predictors of lower exercise capacity in patients with cancer
    Ruben Evertz, Christine Diehl, Katharina Gödde, Miroslava Valentova, Tania Garfias-Veitl, Tobias R. Overbeck, Friederike Braulke, Alessia Lena, Sara Hadzibegovic, Annalen Bleckmann, Ulrich Keller, Ulf Landmesser, Alexander O. König, Gerd Hasenfuss, Andrea
    Scientific Reports.2023;[Epub]     CrossRef
  • NEUROCANTRIAL: study protocol for a randomised controlled trial of a pain neuroscience education programme in adults with cancer pain
    Leidy Tatiana Ordoñez-Mora, Ilem D Rosero, Marco Antonio Morales-Osorio, Rocío Guil, Giancarlo Quintero Jordan, Julian Alberto Agudelo Jimenez, Katherine Gonzalez-Ruiz, Juan Carlos Avila-Valencia
    BMJ Open.2023; 13(9): e071493.     CrossRef
  • Differences in Health-Related Quality of Life in Older People with and without Sarcopenia Covered by Long-Term Care Insurance
    Masahiro Kitamura, Kazuhiro P. Izawa, Kodai Ishihara, Peter H. Brubaker, Hiroaki Matsuda, Soichiro Okamura, Koji Fujioka
    European Journal of Investigation in Health, Psychology and Education.2022; 12(6): 536.     CrossRef
  • Associations of Physical Activity and Handgrip Strength with Health-Related Quality of Life in Older Korean Cancer Survivors
    Jeonghyeon Kim, Seamon Kang, Donghyun Kim, Hyunsik Kang
    Cancers.2022; 14(24): 6067.     CrossRef
  • Differences in the Relationships Between Muscle Strength, Muscle Mass, Balance Function, and Quality of Life for Middle-Aged and Older Breast Cancer Survivors
    Shinichiro Morishita, Ryuichi Kasahara, Yuichi Yamamoto, Ryohei Jinbo, Aya Takano, Mitsuhiko Yasuda, Atsuhiro Tsubaki, Osamu Aoki, Jack B. Fu, Tetsuya Tsuji
    Integrative Cancer Therapies.2022;[Epub]     CrossRef
  • 4,387 View
  • 89 Download
  • 10 Web of Science
  • 9 Crossref
Risk Factors of Cardiovascular Disease according to Alcohol Behavioral Change after Cancer Diagnosis
Eun Mi Bae, In Young Cho, Ji-Hye Jun, Kiheon Lee, Ju Young Kim, Woo Kyung Bae, Hyejin Lee, Jong Soo Han, Se Young Jung, Kee Hyuck Lee, Sarah Kim, Hye Yeon Koo, Sang Jin Cho, Houbuem Lee, Chuelmin Paek
Korean J Fam Med 2020;41(4):222-228.   Published online April 22, 2020
DOI: https://doi.org/10.4082/kjfm.18.0119
Background
Problem drinking increases the incidence of all-cause mortality and specific cancers, and persistent drinking is associated with cardiovascular disease in certain cancer survivors. This study analyzed the cardiovascular risk factors before and after diagnosis in Korean cancer survivors.
Methods
Data for the period between 2002 and 2013 were collected from the National Health Insurance Service Health-Examinee Cohort Database. Among the 27,835 patients included, those with moderate alcohol consumption before and after cancer diagnosis were excluded. Problem drinking was defined as males under 65 years consuming over 14 glasses a week, and males over 65 years or females consuming over seven glasses a week. A t-test, chi-square test, and linear regression analysis were performed for differences in cardiovascular risk factors and differences according to cancer types.
Results
There was a difference in the body mass index, systolic and diastolic blood pressure, and total cholesterol among patients who became moderate drinkers after diagnosis, but fasting blood glucose did not show any significant changes. Risk factors for cardiovascular disease were analyzed in patients with liver, stomach, rectal, and breast cancer with improved drinking behavior, and there were significant differences in body mass index, systolic and diastolic blood pressure, fasting blood glucose, and total cholesterol in stomach cancer patients.
Conclusion
Moderate drinking can lower cardiovascular risk in cancer survivors, and among the many drinking-related cancers, stomach cancer patients demonstrated significantly reduced cardiovascular risk factors.

Citations

Citations to this article as recorded by  
  • Problem Drinking in Cancer Survivors
    Seung-Won Oh
    Korean Journal of Family Medicine.2020; 41(4): 205.     CrossRef
  • 4,809 View
  • 114 Download
  • 1 Web of Science
  • 1 Crossref

Review Article

Cancer Survivorship in Primary Care
Jihun Kang, Eun Ju Park, Jungkwon Lee
Korean J Fam Med 2019;40(6):353-361.   Published online November 20, 2019
DOI: https://doi.org/10.4082/kjfm.19.0108
With the early detection of cancer and improvement in cancer therapy, the number of cancer survivors is rapidly increasing. This number is expected to reach 2 million by the end of 2019. Cancer survivors struggle with not only cancer-related health problems but also diverse acute and chronic diseases. These health issues make cancer survivorship more complex, and proper care coordination is necessary. This study aimed to summarize the definition of cancer experience and management of cancer survivors, specifically focused on gastric, colorectal, lung, breast, thyroid, prostate, and cervical cancers. Furthermore, it aimed to discuss the role of primary care in cancer survivorship and survivorship care models and the National Policy for Cancer Survivors and Future Challenges.

Citations

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  • Supporting Life Adjustment in Patients With Lung Cancer Through a Comprehensive Care Program: Protocol for a Controlled Before-and-After Trial
    Wonyoung Jung, Alice Ahn, Genehee Lee, Sunga Kong, Danbee Kang, Dongok Lee, Tae Eun Kim, Young Mog Shim, Hong Kwan Kim, Jongho Cho, Juhee Cho, Dong Wook Shin
    JMIR Research Protocols.2024; 13: e54707.     CrossRef
  • It’s Not Always Easy: Cancer Survivorship Care in Primary Care Settings
    Mirna Becevic, Allison B. Anbari, Jane A. McElroy
    Journal of Cancer Education.2023; 38(5): 1592.     CrossRef
  • Factors Associated with Sleep Disorder among Korean Cancer Survivors: A Cross-Sectional Study
    Hyeonjin Cho, Wonyoung Jung, Dong Wook Shin, Jinyoung Shin, Yun-Mi Song
    Korean Journal of Family Medicine.2023; 44(4): 224.     CrossRef
  • Exploring socio-demographic, physical, psychological, and quality of life-related factors related with fear of cancer recurrence in stomach cancer survivors: a cross-sectional study
    Jinyoung Shin, Dong Wook Shin, Jungkwon Lee, JiHye Hwang, Ji Eun Lee, BeLong Cho, Yun–Mi Song
    BMC Cancer.2022;[Epub]     CrossRef
  • Interdisciplinary Approaches to Survivorship with a Focus on the Low-grade and Benign Brain Tumor Populations
    Stacey L. Worrell, Michelle L. Kirschner, Rhonna S. Shatz, Soma Sengupta, Melissa G. Erickson
    Current Oncology Reports.2021;[Epub]     CrossRef
  • 7,617 View
  • 147 Download
  • 6 Web of Science
  • 5 Crossref
Original Articles
Trends in Influenza Vaccination Coverage Rates among Korean Cancer Survivors: Analysis of the Korea National Health and Nutrition Examination Survey III–VI
Ye-Seul Kim, Jae-woo Lee, Hee-Taik Kang, Yonghwan Kim, Hyo-Sun You
Korean J Fam Med 2020;41(1):45-52.   Published online November 11, 2019
DOI: https://doi.org/10.4082/kjfm.18.0165
Background
Few studies have reported on the trends in influenza vaccination rates among cancer survivors in Korea. We investigated these trends over a recent 11-year period (2005–2015).
Methods
Data were obtained from the Korea National Health and Nutrition Examination Survey (KNHANES) III– VI (2005–2015). After excluding individuals younger than 40 years of age, the participants included 2,210 cancer survivors (861 men and 1,349 women). We categorized these study participants into four groups according to age and sex.
Results
The influenza vaccination rate decreased significantly among male cancer survivors, with rates of 74.8, 64.7, 56.2, and 55.2% (β coefficient=-0.257, P for trend <0.001) in KNHANES III, VI, V, and VI, respectively. While influenza vaccination rates decreased significantly among older male cancer survivors (≥65 years) (β coefficient=-0.359, P for trend=0.017), they increased among older female cancer survivors (β coefficient=0.375, P for trend=0.011) from 2005 to 2015.
Conclusion
Influenza vaccination rates in older cancer survivors significantly decreased in men but increased in women in successive KNHANES phases. Efforts are needed to improve immunization education and awareness, especially in older male cancer survivors.

Citations

Citations to this article as recorded by  
  • Influenza vaccine effectiveness in immunocompromised patients with cancer: A Danish nationwide register‐based cohort study
    Lau Amdisen, Lars Pedersen, Niels Abildgaard, Christine Stabell Benn, Deirdre Cronin‐Fenton, Signe Sørup
    Cancer.2025;[Epub]     CrossRef
  • The coverage of influenza vaccination and predictors of influenza non-vaccination in Danish cancer patients: A nationwide register-based cohort study
    Lau Amdisen, Lars Pedersen, Niels Abildgaard, Christine Stabell Benn, Mikael Rørth, Deirdre Cronin-Fenton, Signe Sørup
    Vaccine.2024; 42(7): 1690.     CrossRef
  • Vaccination uptake among post-treatment cancer survivors: A multi-vaccine scoping review
    Kavita Renduchintala, Mariana Arevalo, Gabriella Fonseca, Mary Katherine Haver, Clement K. Gwede, Smitha Pabbathi, Shannon M. Christy
    Vaccine.2024; 42(22): 125995.     CrossRef
  • Seasonal influenza vaccination among cancer patients: A systematic review and meta-analysis of the determinants
    George N. Okoli, Otto L.T. Lam, Tiba Abdulwahid, Christine J. Neilson, Salaheddin M. Mahmud, Ahmed M. Abou-Setta
    Current Problems in Cancer.2021; 45(2): 100646.     CrossRef
  • A cross‐sectional study of factors associated with influenza vaccination in Korean cancer survivors
    Ji Eun Lee, Dong Wook Shin, Jinyoung Shin, In Young Cho, Jungkwon Lee, JiHye Hwang, BeLong Cho, Yun‐Mi Song
    European Journal of Cancer Care.2021;[Epub]     CrossRef
  • Influenza Vaccination Status and Its Affecting Factors among Stroke Survivors: Findings from the Korea National Health and Nutrition Examination Survey
    Eung-Joon Lee, Oh Deog Kwon, Seung Jae Kim
    Vaccines.2021; 9(7): 763.     CrossRef
  • 7,232 View
  • 111 Download
  • 6 Web of Science
  • 6 Crossref
Background
Cancer survivors are at a higher risk of primary cancer recurrence and development of second primary cancer. In both cases, early disease detection is crucial. This cross-sectional study assessed cancer screening participation rates according to cancer history.
Methods
Data were obtained from the 2010–2012 Korea National Health and Nutrition Examination Survey for 12,500 participants. Of these, 624 cancer survivors were enrolled in this study. Sampling weights were applied to maintain the representativeness of the Korean adult population.
Results
Overall 2-year cancer screening rates prior to the survey in male and female cancer survivors were 59.9% and 73.7%, respectively, while opportunistic cancer screening rates were 33.5% and 52.1%, respectively. The odds ratios (95% confidence interval) of the overall cancer screening among the cancer survivors, compared to others, were 1.16 (0.79–1.72) in male and 1.78 (1.20–2.63) in female participants, after the adjustment for confounding variables. The odds ratios (95% confidence interval) for opportunistic cancer screening and National Cancer Screening Program among cancer survivors were 1.56 (1.07–2.27) and 0.80 (0.53–1.21) in males and 2.05 (1.46–2.88) and 0.66 (0.46–0.95) in females.
Conclusion
Female cancer survivors showed a higher rate of overall and opportunistic cancer screening than did the male cancer survivors. Further efforts are required to improve cancer screening among male cancer survivors.

Citations

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  • Cancer screening and its associated factors in hypertensive individuals: new insights from the 2021 STEPs national study in Iran
    Dorsa Salabat, Sheida Sarrafzadeh, Ozra Tabatabaei-Malazy, Nazila Rezaei, Sepehr Khosravi, Ali Golestani, Farzad Kompani, Samaneh Akbarpour
    BMC Public Health.2025;[Epub]     CrossRef
  • Temporal Trend in Uptake of the National General Health Checkups and Cancer Screening Program among Korean Women with Breast Cancer
    Thi Xuan Mai Tran, Soyeoun Kim, Chihwan Cha, Boyoung Park
    Cancer Research and Treatment.2024; 56(2): 522.     CrossRef
  • Prediction Model for Hypertension and Diabetes Mellitus Using Korean Public Health Examination Data (2002–2017)
    Yong Whi Jeong, Yeojin Jung, Hoyeon Jeong, Ji Hye Huh, Ki-Chul Sung, Jeong-Hun Shin, Hyeon Chang Kim, Jang Young Kim, Dae Ryong Kang
    Diagnostics.2022; 12(8): 1967.     CrossRef
  • 6,125 View
  • 66 Download
  • 3 Web of Science
  • 3 Crossref
Breast and Cervical Cancer Screening Behavior in Female Cancer Survivors: The Korea National Health and Nutrition Examination Survey, 2007–2012
Eun-Ae Lee, Jinyoung Shin, Eun-Joo Hwang, Jung-Woong Lee
Korean J Fam Med 2017;38(3):116-121.   Published online May 23, 2017
DOI: https://doi.org/10.4082/kjfm.2017.38.3.116
Background

The aim of this study was to compare breast and cervical cancer screening rates between female cancer survivors and a population without cancer to identify factors related to cervical and breast cancer screening in cancer survivors.

Methods

We included 17,765 adults (738 cancer survivors and 17,027 individuals without cancer) in this study, all of whom who were 30 years of age or older and participated in the Fourth and Fifth Korean National Health and Nutritional Examination Surveys from 2007–2012. Multiple logistic regression analysis was performed to identify factors related to cervical and breast cancer screening uptake in female cancer survivors.

Results

The screening rate for breast cancer was 56.6%, which was higher than that in the non-cancer control group (P=0.001). The screening rate for cervical cancer was 51.4%, which was not different from that of the non-cancer control group. In terms of breast cancer screening, cancer survivors showed no significant difference in the rate of screening 5 years after their cancer diagnosis. However, cervical cancer survivors were less likely to have cervical cancer screening 10 years after their cancer diagnosis. There was no significant association between cancer screening and sociodemographic factors.

Conclusion

Breast and cervical cancer screening rates in Korean female cancer survivors are low. Secondary primary cancer screening of female cancer survivors needs to be planned in a comprehensive manner, with the consideration of influences beyond sociodemographic factors.

Citations

Citations to this article as recorded by  
  • Temporal Trend in Uptake of the National General Health Checkups and Cancer Screening Program among Korean Women with Breast Cancer
    Thi Xuan Mai Tran, Soyeoun Kim, Chihwan Cha, Boyoung Park
    Cancer Research and Treatment.2024; 56(2): 522.     CrossRef
  • Screening Adherence for Second Primary Malignancies in Breast Cancer Survivors: Behaviors, Facilitators, and Barriers to Enhance Quality Care
    Fernanda Mesa-Chavez, Misael Salazar-Alejo, Cynthia Villarreal-Garza
    Seminars in Oncology.2024; 51(5-6): 156.     CrossRef
  • RESEARCH ON THE IMPROVED IMAGE TRACKING ALGORITHM OF ATHLETES’ CERVICAL HEALTH
    Jingjing Jiang
    Revista Brasileira de Medicina do Esporte.2021; 27(5): 476.     CrossRef
  • Basic Findings Regarding Breast Cancer in Korea in 2015: Data from a Breast Cancer Registry
    Sang Yull Kang, Yoo Seok Kim, Zisun Kim, Hyun-Yul Kim, Se Kyung Lee, Kyu-Won Jung, Hyun Jo Youn
    Journal of Breast Cancer.2018; 21(1): 1.     CrossRef
  • 4,511 View
  • 46 Download
  • 6 Web of Science
  • 4 Crossref
Risk of Cardiovascular Disease Using Framingham Risk Score in Korean Cancer Survivors
Ji-Hyun So, Jung-Kwon Lee, Jin-Young Shin, Wan Park
Korean J Fam Med 2016;37(4):235-241.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.235
Background

Cardiovascular disease is an important cause of morbidity and mortality in cancer survivors. The aim of this study was to investigate the modifiable cardiovascular disease risk factors and 10-year probability of the disease based on the Framingham risk score in cancer survivors, compared with the general population.

Methods

A total of 1,225 cancer survivors and 5,196 non-cancer controls who participated in the 2007–2013 Korea National Health and Nutrition Examination Surveys were enrolled. We assessed modifiable cardiovascular disease risk factors including smoking, body mass index, physical inactivity, high blood pressure, high cholesterol, and elevated blood glucose level. The 10-year probability of cardiovascular disease was determined by applying the Framingham cardiovascular disease risk equation among cancer survivors and non-cancer controls, ranging from 30 to 74 years old who had no overt cardiovascular diseases.

Results

The proportion of subjects who had higher fasting glucose levels, hemoglobin A1c levels, systolic blood pressure, and low density lipoprotein cholesterol levels, and those who had lower high density lipoprotein cholesterol levels was significantly higher in the cancer survivors than in the non-cancer controls. The average 10-year probability of cardiovascular disease among the cancer survivors was higher than that in the non-cancer controls in both men and women. The average 10-year probability of cardiovascular disease in relation to the cancer type was significantly higher in patients with hepatic, colon, lung, breast, and gastric cancer.

Conclusion

Cancer survivors have a higher cardiovascular disease risk and 10-year probability of cardiovascular disease than non-cancer controls. Control of cardiovascular disease risk factors and implementation of a well-defined cardiovascular disease prevention program are needed for treating cancer survivors.

Citations

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Factors Associated with Depression Assessed by the Patient Health Questionnaire-2 in Long-Term Cancer Survivors
Ae-Jin Goo, Yun-Mi Song, Jinyoung Shin, Hyeonyoung Ko
Korean J Fam Med 2016;37(4):228-234.   Published online July 21, 2016
DOI: https://doi.org/10.4082/kjfm.2016.37.4.228
Background

This cross-sectional study aimed to evaluate the prevalence of depressive disorders and factors associated in long-term cancer survivors.

Methods

A total of 702 long-term cancer survivors over 5-years in remission were recruited in a university-affiliated tertiary hospital in Korea. Self-report using the Patient Health Questionnaire-2 and the Fatigue Severity Scale assessed depression and fatigue, respectively. Demographic characteristics, cancer-related clinical characteristics, comorbidity, health behaviors, and physical symptoms were assessed through the review of medical records or a structured self-administered questionnaire.

Results

We identified 26.1% of patients who had a depressed mood or displayed a loss of interest. The most prevalent primary site of cancer was the stomach (65.2%), followed by lung, breast, colorectal, and thyroid cancer. We also found that 5.7% of subjects experienced double or triple primary cancers. Larger proportion among depressive group (89.1%) complained at least one physical problem than among non-depressive group (53.2%). Physical symptoms including sleep problems, dry mouth, indigestion, pain, decreased appetite, and febrile sense were more frequent in the depressive group than in the non-depressive group. The Fatigue Severity Scale scores were higher in the depressive group than in the non-depressive group (P<0.001). Multiple logistic regression analysis showed that the highest tertile level of fatigue (odds ratio, 7.31; 95% confidence interval, 3.81–14.02) was associated with the increased risk of depression.

Conclusion

These findings suggest that careful concern about depression is necessary in long-term cancer survivors. Fatigue may be a surrogate sign for depression, and warrants further evaluation.

Citations

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Factors Associated with Fatigue in Korean Gastric Cancer Survivors
Wan Park, Jung-Kwon Lee, Cho-Rong Kim, Jin-Young Shin
Korean J Fam Med 2015;36(6):328-334.   Published online November 20, 2015
DOI: https://doi.org/10.4082/kjfm.2015.36.6.328
Background

Gastric cancer is the second most common cancer in Korea. Fatigue is a common symptom among cancer survivors. The aim of this study was to identify factors associated with fatigue in gastric cancer survivors.

Methods

Data were analyzed from 199 gastric cancer survivors who visited a cancer survivor outpatient clinic from July 2013 to June 2014. Patients were surveyed using a questionnaire containing a fatigue severity scale (FSS) and questions regarding associated symptoms. Participants were divided into fatigue (FSS) and non-fatigue groups based on FSS scores (≥4 and <4, respectively). Age, sex, weight, body mass index, cancer stage, pathology, surgery type, chemotherapy, radiotherapy, comorbid disease, family history of cancer, smoking, alcohol consumption, exercise, and laboratory results were investigated.

Results

The fatigue and non-fatigue groups contained 42 and 157 survivors, respectively. Their mean age was 58 years, and the mean post-operative period was 6.58 years. Arthralgia (odds ratio [OR], 12.95; 95% confidence interval [CI], 3.21-52.34), dyspnea (OR, 10.54; 95% CI, 2.94-37.80), dyspepsia (OR, 8.26; 95% CI, 2.63-25.96), changed bowel habits (OR, 4.56; 95% CI, 1.09-19.11), anemia (OR, 3.18; 95% CI, 1.26-8.05), and regular exercise (OR, 0.31; 95% CI, 0.12-0.77) were significantly associated with fatigue in gastric cancer survivors, while weight, treatment, and depressive mood were not.

Conclusion

Arthralgia, dyspnea, dyspepsia, bowel habit change, anemia, and regular exercise are associated with fatigue in gastric cancer survivors.

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