Background
Although the number of medical institutions running a smoking cessation clinic is on the rise, there remains a paucity of research on the long- and short-term success rates of smoking cessation programs, as well as on smoking relapse rates, before and after project implementation. This study assessed the general characteristics of patients visiting the smoking cessation clinic, success rate of smoking cessation in the short term, and risks of relapse.
Methods
Medical records from March 2015 to April 2017 were analyzed and telephone surveys were conducted with 151 smokers who visited a hospital smoking cessation clinic from March 2015 to April 2017.
Results
Of the 139 smokers who were eligible for follow-up, 22 (15.8%) failed to quit smoking initially. The clinic’s 6-month success rate of smoking cessation was 64.83%. Those with higher medication compliance had a lower risk of primary failure (odds ratio, 0.056; 95% confidence interval, 0.005–0.609), whereas those with higher age (hazard ratio [HR], 0.128; P=0.0252) and a greater number of visits to the clinic (HR, 0.274; P=0.0124) had a lower risk of relapsing.
Conclusion
The risk of primary failure to quit was higher with low medication compliance, and that of relapsing was higher with lower age and fewer number of clinic visits. Various evaluation and analysis methods can be carried out in the future based on the accumulated data for maintenance of smoking cessation and relapse prevention.

Citations

• Development of a Risk Score to Predict Short-term Smoking Relapse Following an Inpatient Smoking Cessation Intervention
  Hwang Sik Shin, Yoon Hyung Park, Sung Soo Lee, Yong Jin Cho, Jun Tack Kwon, Youngs Chang, Mee-Ri Lee, Young Hwangbo
  Asia Pacific Journal of Public Health.2024; 36(4): 329.     CrossRef
• Associations between Nicotine Dependence, Smartphone Usage Patterns, and Expected Compliance with a Smoking Cessation Application among Smokers
  Oh Beom Kwon, Chihoon Jung, Auk Kim, Sang Won Park, Gihwan Byeon, Seung-Joon Lee, Woo Jin Kim
  Healthcare Informatics Research.2024; 30(3): 224.     CrossRef
• The Current Status and Challenges of National Smoking Cessation Support Program in Korea
  Seung-Won Oh
  Korean Journal of Family Medicine.2019; 40(6): 351.     CrossRef

Citations

• The Effect of Varenicline on Smoking Cessation in Hospitalized Patients: A Systematic Review and Meta-Analysis
  Mahshid Aryanpur, Raheb Ghorbani, Sajjad Rashno, Gholamreza Heydari, Mehdi Kazempour-Dizaji, Zahra Hessami, Narges Ghorbani
  Addiction and Health.2024; 16(2): 122.     CrossRef
• Public Health Intervention for Smoking Cessation
  Soo Young Kim
  Korean Journal of Family Medicine.2021; 42(5): 343.     CrossRef
• The effect of a multidisciplinary approach for smoking cessation in patients with Crohn’s disease: Results from an observational cohort study
  Pierachille Santus, Dejan Radovanovic, Davide Raiteri, Stefano Pini, Giuseppe Spagnolo, Giovanni Maconi, Maurizio Rizzi
  Tobacco Induced Diseases.2020;[Epub]     CrossRef
• Using Lean Quality Improvement Tools to Increase Delivery of Evidence-Based Tobacco Use Treatment in Hospitalized Neurosurgical Patients
  Laurel Sisler, Oluwaseun Omofoye, Karina Paci, Eldad Hadar, Adam O. Goldstein, Carol Ripley-Moffitt
  The Joint Commission Journal on Quality and Patient Safety.2017; 43(12): 633.     CrossRef

Background
Varenicline is recently known as smoking cessation medicine has no results of researches conducted in the actual practice settings except for incipient clinical trials. This research attempted to analyze the factors for smoking cessation by using Varenicline prescribed in the family clinic, and the efficacy of Varenicline. Methods: Brief smoking cessation education was conducted on 140 people who visited the Department of Family Medicine at Dankook University and Varenicline was prescribed for them. This research checked whether smoking was stopped or not after six months and analyzed the factors for succeeding in smoking cessation. Results: Varenicline was prescribed for the 140 people. After six months, 46 smokers were successful in smoking cessation, representing the rate of success of 35.4%, and after 12 months, 31 people of 83 people were successful in smoking cessation, representing the rate of success of 37.3%. The group less smoke than 24.3 cigarettes/day (the average daily smoking amount) has higher quit rate than the group more smoke than 24.3 by 4.9 times. The group takes Varenicline longer than 26.7 days (the average Varenicline dosage period) has higher quit rate than the group takes Varenicline shorter than 26.7 by 4 times. Smoking-cessation rate was 4.5 times when trying to stop smoking by the doctor's recommendation. It was higher than when trying to stop smoking by self-determination. In the multivariate analysis, there were significant relationships in daily smoking amount, dosage and period of Varenicline, and motivation of visits.Conclusion: Varenicline is one of the useful medication for quitting smoking in family practice setting. Better compliance of medicine shows better quitting rate.

Citations

• Compliance and Effectiveness of Smoking Cessation Program Started on Hospitalized Patients
  Gun Hee Shin, Sung Won Yi, Yoo Seock Cheong, Eal Whan Park, Eun Young Choi
  Korean Journal of Family Medicine.2016; 37(3): 149.     CrossRef
• Adherence to Varenicline and Abstinence Rates for Quitting Smoking in a Private Health Promotion Center-Based Smoking Cessation Clinic
  Jin-Young Lee, Min Ji Kim, Hee-Jung Jun, Mira Kang, Ah Rham Park, Dae Eun Oh, Yoon-Ho Choi, Jung Hye Hwang
  Tuberculosis and Respiratory Diseases.2012; 72(5): 426.     CrossRef

Background
Varenicline is known to have higher effect for smoking cessation than existing pharmacotherapies, including Bupropion and Nicotine replacement therapy, however, it can also bring about adverse effects such as problems in compliance due to the complicated dosage, side effects of high frequency, and financial burden resulted from a long term treatment. Moreover, the effect for smoking cessation with group program and non-pharmacotherapy, including financial. incentives, E-mails or SMS is well known, but, the study on their combination is rare. Therefore, in the present study, we tried to evaluate two things; the effect for smoking cessation with multi-modal intervention, and the compliance of Varenicline Methods: From July 2008 to February 2009, we conducted the multi-modal smoking cessation program for 30 volunteers in Dankook university. This program consisted short course of Varenicline, financial incentives, E-mail and short messageservice. Results: The continuous abstinence rate for weeks 9 throught 12 was 76.7% and for weeks 9 through 24 was 43.3%. Multivariate analysis revealed that duration of Varenicline treatment was significant factor affecting 12-week continuous abstinence rate. The average duration of Varenicline treatment was 17.1 (±10.8) days and 54.0% took Varenicline as directed. The most common adverse events were nausea (40.0%) and insomnia (23.3%).Conclusion: Multi-modal intervention (short course of Varenicline, financial incentive, E-mail and short message service) was effective for smoking cessation with high continuous abstinence rates in a university. We suggest multi-modal intervention because compliance of Varenicline seems to be low in real setting.

Citations

• Interventions to increase adherence to medications for tobacco dependence
  Gareth J Hollands, Felix Naughton, Amanda Farley, Nicola Lindson, Paul Aveyard
  Cochrane Database of Systematic Reviews.2019;[Epub]     CrossRef
• Adherence to Pharmacological Smoking Cessation Interventions: A Literature Review and Synthesis of Correlates and Barriers
  Lauren R Pacek, F Joseph McClernon, Hayden B Bosworth
  Nicotine & Tobacco Research.2018; 20(10): 1163.     CrossRef
• Interventions to increase adherence to medications for tobacco dependence
  Gareth J Hollands, Máirtín S McDermott, Nicola Lindson-Hawley, Florian Vogt, Amanda Farley, Paul Aveyard
  Cochrane Database of Systematic Reviews.2015;[Epub]     CrossRef
• Efficacy of Smoking Cessation and Prevention Programs by Intervention Methods: A Systematic Review of Published Studies in Korean Journals during Recent 3 Years
  Hye Kyeong Kim, Ji Yeon Park, Eun Joo Kwon, Seung Hee Choi, Han-Ik Cho
  Korean Journal of Health Education and Promotion.2013; 30(5): 61.     CrossRef
• A Short-Term Effectiveness of Smoking Cessation Intervention in Outpatient Department of Pulmonology
  Chang Dong Yeo, Hyeon Hui Kang, Ji Young Kang, Sung Kyoung Kim, Myung Sook Kim, Seung Soo Kim, Sang Haak Lee, Hwa Sik Moon
  Tuberculosis and Respiratory Diseases.2011; 71(2): 114.     CrossRef