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Korean J Fam Med > Volume 30(9); 2009 > Article
Korean Journal of Family Medicine 2009;30(9):723-727.
DOI: https://doi.org/10.4082/kjfm.2009.30.9.723    Published online September 20, 2009.
One Case of Malignant Mixed Mullerian Tumor Developed in a Postmenopausal Woman under Hormone Therapy.
In Cheol Hwang, Myoung Jin Kuk, Kyoung Kon Kim, Ki Bum Lee, Seo Young Na, Kyoung Sik Lee, Heuy Sun Suh
1Department of Family Medicine, Gachon University Gil Hospital, Incheon, Korea. zaduplum@aim.com
2Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, Korea.
호르몬 치료를 받던 폐경 후 여성에서 발생한 악성 혼합 뮐러종양 1예
황인철, 국명진, 김경곤, 이기범, 나서영, 이경식, 서희선
1
2
Abstract
Hormone therapy for peri- and postmenopausal women is widely used for relieving vasomotor symptoms or preventing osteoporosis. Even though exogenous hormone is the most common cause of vaginal bleeding in postmenopausal women under hormone therapy, in clinical practice, physicians must never exclude the possibility of endometrial disorders, such as endometrial hyperplasia or cancer. Taking thorough medical history and performing physical and pelvic examinations are essential for the evaluation of abnormal uterine bleeding in menopausal hormone therapy. Transvaginal ultrasonography, endometrial aspiration biopsy, dilatation and curettage, and hysteroscopy are the options which physicians may use. This case is about a woman with continuous combined hormone therapy for 5 years who had experienced rather sudden onset of vaginal spotting lasting for several months and was fi nally diagnosed as having malignant mixed Müllerian tumor. Our purpose is to inquire into the proper approaching steps for vaginal bleeding in menopausal hormone therapy.
Key Words: Hormone Therapy; Abnormal Uterine Bleeding; Malignant Mixed Mü; llerian Tumor
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