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Journal of the Korean Academy of Family Medicine 1989;10(11):30-35.
Published online November 1, 1989.
두가지 국산B형 간염 백신 투여후 항체 양전율의 비교
박계숙 이혜리 윤방부
연세대학교의과대학 가정의학교실
Abstract
HBs Ag and Anti-HBs Tests among serologic markers of Hepatitis B virus were used as testing criteria for 2130 students who took the regular health examination at Yonsei University, which was held twice from October 1987 to May 1988.
1. The HBs Ag was detected in 119 out of 2130 students with a positive rate of 5.59%. Of them, the healthy carriers, who had a normal L.F.T.(OT, PT), were 94 students, and 25 students had an OT, PT higher than 30 IU/ml.
2. The positivity of the Anti-HBs was 13.62%, they therefore had immunity.
3. After three HB vaccinations, 173 out of 217 students showed positivity to the Anti-HBs(79.7%).
4. There was no valid statistic difference between the two groups in the RIA test ; one group had the Hepavax injection, the other group had Hepaccine.
In Conclusion, it is economical to execute the RPHA test which detects HBs Ag with a screening test, before the HB vaccination, Anti-HBs can be testec in a PHA test first. When the response is negative, Anti-HBs of the serum from those who showd a negative response could be measured in an RIA test.
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