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Journal of the Korean Academy of Family Medicine 2007;28(2):120-126.
Published online February 10, 2007.
Alcohol and the Metabolic Syndrome in Korean Women.
Won Ki Hong, Jong Sung Kim, Jin Gyu Jung, Sung Soo Kim, Chan Il Park, Keun Bae Kim, In Wook Jung
Department of Family Medicine, Chungnam National University Hospital, Daejeon, Korea. jskim@cnuh.co.kr
여성 음주와 대사증후군
홍원기,김종성,정진규,김성수,박찬일,김근배,정인욱
충남대학교 의과대학 가정의학교실
Abstract
Background
Moderate drinking has been known to be associated with a risk of reduced cardiovascular disease morbidity and mortality. The metabolic syndrome has been associated with a risk of increased cardiovascular diseases. Because drinking is considered as a risk factor of the metabolic syndrome, this study was performed to examine the association between alcohol drinking and the metabolic syndrome in Korean women. Methods: The subjects were 262 women who visited the health promotion center of Chungnam National University Hospital for general health check-up. The metabolic syndrome was diagnosed according to the definition by the National Cholesterol Education Program Adult Treatment Panel III. The abdominal obesity guidelines for waist circumference applied the WHO Asian Pacific Guideline. The subjects were classified into nondrinking, moderate drinking (≤1 drink), and heavy drinking (>1 drink) according to their drinking amount per day. The relationship between the components of the metabolic syndrome and drinking state were investigated. The prevalence of the metabolic syndrome was compared according to the drinking state. Results: The women with moderate drinking showed significantly lower levels of triglyceride than nondrinkers (P<0.05). The women with drinking showed significantly higher levels of HDL cholesterol than nondrinkers (moderate drinkers P<0.05, heavy drinkers P<0.05). Considering nondrinkers as standard, the risk of the metabolic syndrome was significantly low in women with moderate drinking (odds ratio=0.43, 95% confidence interval: 0.22∼0.84, P=0.013). Conclusion: The results of the present study suggest that moderate drinking is related to a lower rate of the metabolic syndrome in Korean women. (J Korean Acad Fam Med 2007;28:120-126)
Key Words: metabolic syndrome, drinking, women
초록
연구배경: 적절한 음주는 심혈관 질환의 이환율과 이로 인한 사망률의 감소와 관계가 있다. 대사증후군은 심혈관 질환의 위험도를 높이는 질환으로 알려져 있다. 음주는 대사증후군의 위험을 높이는 데 영향을 주는 인자로 여겨지고 있어 여성의 음주와 대사증후군 간의 관계를 알아보기 위하여 시행하였다. 방법: 2005년 3월부터 5월까지 대전광역시 소재 일개 대학병원 종합검진센터에서 종합검진을 받은 262명의 여성을 대상으로 하였다. 대사증후군의 진단은 National Cholesterol Education Program, Adult Treatment Panel III의 기준에 근거하였고, 그 중 허리둘레는 세계보건기구 아시아-태평양 기준에 따랐다. 음주상태는 하루 음주량을 조사하여 비음주군, 적절음주군(1잔 이하), 과음군(1잔 초과)으로 분류하였다. 대사증후군의 구성요소들과 음주와의 연관성을 조사하였고 음주상태에 따라 대사증후군의 빈도를 비교하였다. 결과: 여성 적절음주군은 중성지방이 비음주군에 비해 유의하게 낮았다 (P<0.05). 여성 음주군들은 고밀도지단백이 비음주군에 비해 유의하게 높았다(적절음주군 P<0.05, 과음군 P<0.05). 적절음주군은 비음주군에 비해 대사증후군의 위험이 낮게 관찰되었다(Odds ratio=0.43, 95% Confidence interval: 0.22∼0.84, P=0.013). 결론: 여성에서 하루 1잔의 적절한 음주는 대사증후군의 위험이 낮았다.
중심 단어: 대사증후군, 음주, 여성


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