Journal of the Korean Academy of Family Medicine 1989;10(3):26-35.
Published online March 1, 1989.

입원환자와 외래환자에 있어서 요로감염의 원인균과 항균제 감수성 결과에 관한 고찰

김석현 남기남 김대현 배철영 이혜리 윤방부

연세대학교의과대학 가정의학교실

Abstract

Urinary tract infections are quite common next to respiratory tract infections, and are more important they often progressive and lead to irreversible impairment of the kidney function. Hence urinary tract infections, whether encountered in hospital of in general practice, usually raquires rapid and energetic treatment.
1,920 cases with urinary tract infections were evaluated for observation of causative organisms and antibiotic sesceptability in in-patients and out-patients at Yonsei Medical Center during one year from january, 1987 to december, 1987.
The following results were obtained.
1) 1,290 patients (in-patients:1065, out-patients:225), (male:477, female:813) were observed. The ratio of males to females was 1:1.7.
2) The most common pathogen were E. coli(43.5%), Enterococcus, Pseudomonas, Klebsiella, Enterobacter in the order.
The predominant urinary pathogens in in-patients were Enterococcus, Pseudomonas, Klebsiella, Enterobacter as opposed to E. coli in out-patients.
The prevalence of other infecting agent in both groups is almost identical.
E.coli was the causative organism in 58.4% of the infections in the female.
3) The incidence of mixed urinary tract infections was 9.9% and their predominant pathogen was Pseudomonas.
4) The susceptability rates from out-patient infections were generally more sensitive than those from in-patient infections.
Amikacin and cefotaxime were found to be the most effective antibiotic in both in-patient and out-patient infections.
The susceptability rates of ampicillin, tetracyclin, chloramphenicol were very low in both groups.
5) The highest percentage of E.coli were sensitive to cefotaxime and amikacin followed by cefamandole, gentamicin, cefoperazone.
E. coli from out-patients were significantly more sensitive to only gentamicin than those from in-patient infections.
The susceptability rate of Pseudomonas were most sensitive to colistive to colistin and low sensitive gentamicin, carbenicillin, tobramycin and no significant difference between in-patient and out-patient infections.
Klebsiella and Enterobacter were most sensitive to amikacin.
Klebsiella from out-patients were more sensitive over 87.5% to most antibiotics than in-patient infections.
Susceptability rate of Enterococcus was 89% to ampicillin in in-patient and 100% in out-patient infections.