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Korean J Fam Med > Volume 30(12); 2009 > Article
Korean Journal of Family Medicine 2009;30(12):962-971.
DOI: https://doi.org/10.4082/kjfm.2009.30.12.962    Published online December 20, 2009.
Correlation between Endoscopic Severity of Gastroesophageal Reflux Disease (GERD) and Indexes of Obesity.
Ki Byung Lee, Keunmi Lee, Seung Pil Jung
Department of Family Medicine, Yeungnam University College of Medicine, Daegu, Korea. kmlee@med.yu.ac.kr
위식도역류질환의 내시경 중증도와 비만관련 지표들과의 연관성
이기병, 이근미, 정승필
영남대학교 의과대학 가정의학교실
There are many reports that obesity could be associated with gastoesophageal refl ux disease (GERD) but the outcomes are controversial and the studies on correlation between endoscopic severity of GERD and obesity are rare. Therefore, we investigated the association between endoscopic severity of GERD and indexes of obesity. Methods: Among the subjects who visited a health promotion center of a general hospital from January 2007 to March 2008, a total of 527 subjects with typical symptoms of GERD who underwent esophagogastroduodenoscopy and analysis of body composition were enrolled. The endoscopic severity of GERD was classifi ed depending on LA grading classifi cation system. Results: Among 527 subjects, 125 subjects were classifi ed with Non-erosive refl ux disease (NERD) while 254, 105, and 43 subjects were classifi ed as LA grade A, B, and C group, respectively. Men and frequent alcohol drinkers (≥ 5 times/week) were likely to be in higher endoscopic severity group (OR, 2.065 and 2.394, respectively; P < 0.05). If the subject was obese by BMI and waist circumference, it showed a higher possibility of belonging to the higher endoscopic severity group (OR, 2.319 and 2.596, respectively; P < 0.001). In the case of %body fat, the obesity group was more likely to be in the higher endoscopic severity group only in men (OR, 1.906; P < 0.001). Conclusion: Indexes of obesity such as BMI, %body fat (only in men), and waist circumference were related with endoscopic severity of GERD and this relationship is more apparent in men and alcohol drinkers (≥ 5 times/week).
Key Words: Gastroesophageal Refl ux; Esophagogastroduodenoscopy; Obesity; BMI; Waist Circumference; % Body fat
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