| The Association between Helicobacter Pylori Infection and Metabolic Syndrome in Korean Men and Women. |
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Tae Heum Chung, Moon Chan Kim, Chung Hun Choi, Chang Sup Kim |
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Department of Family Medicine, University of Ulsan College of Medicine, Ulsan, Korea. jeongth@uuh.ulsan.kr |
| 한국 성인 남녀에서 헬리코박터 파이로리 감염과 대사증후군과의 관련성 |
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정태흠, 김문찬, 최정헌, 김창섭 |
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울산대학교 의과대학 울산대학교병원 가정의학과 |
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| Abstract |
Background
Metabolic syndrome is a cluster of metabolic abnormalities leading diabetes and cardiovascular diseases. Helicobacter pylori (H. pylori) infection is suggested to be a risk factor of cardiovascular diseases. We aimed to investigate the association between H. pylori infection and metabolic syndrome. Methods: This study was designed with Korean adults having a health check-up in a university hospital in Ulsan from March 2008 to February 2009. The subjects were 17,448 over 20 years old. The analysis was undertaken according to sex separately. The association of H. pylori seropositivity (IgG) with metabolic syndrome components was investigated by multiple linear regression analysis. The association of H. pylori seropositivity with metabolic syndrome was investigated by multiple logistic regression analysis. Results: H. pylori seropositivity was significantly inversely associated with high density lipoprotein cholesterol in men (Coefficient, -0.02; 95% confidence interval [CI], -0.03 to -0.004; P = 0.01). However, H. pylori seropositivity was not significantly associated with metabolic syndrome in both men and women (OR, 1.01; 95% CI, 0.90 to 1.14; P = 0.81 for men; OR, 0.75; 95% CI, 0.55 to 1.02; P = 0.06 for women). Conclusion: H. pylori infection was significantly negatively associated with high density lipoprotein cholesterol in men, but not significantly associated with metabolic syndrome in both men and women. |
| Key Words:
Helicobacter Pylori; IgG Antibody; Metabolic Syndrome |
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